CD247 Products
(CD247 Molecule (CD247))
Categories
The protein encoded by this gene is T-cell receptor zeta, which together with T-cell receptor alpha/beta and gamma/delta heterodimers, and with CD3-gamma, -delta and -epsilon, forms the T-cell receptor-CD3 complex. The zeta chain plays an important role in coupling antigen recognition to several intracellular signal-transduction pathways. Low expression of the antigen results in impaired immune response. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Featured CD247 Categories
CD247 Antibodies
High quality antibodies with extensive validation data.
CD247 ELISA Kits
Reliable ELISA kits for a wide range of species.
CD247 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended CD247 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse
Application
WB, FACS, ICC
Validations
- (1)
- (6)
Cat. No.
ABIN2749060
Quantity
0.1 mg
Datasheet
Datasheet
Reactivity
Human
Application
WB, PLA
Validations
- (7)
Cat. No.
ABIN514136
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IP, IHC (p)
Validations
- (6)
Cat. No.
ABIN560227
Quantity
100 μg
Datasheet
Datasheet
Recommended CD247 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6973490
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Analytical Method
Qualitative Cell ELISA
Validations
Cat. No.
ABIN1380201
Quantity
2 x 96 tests
Datasheet
Datasheet
Recommended CD247 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7122196
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1348582
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN2128420
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our CD247 products
: "Investigation of the Immunomodulatory effect of Berberis vulgaris on core-pulsed dendritic cell vaccine." in: BMC complementary and alternative medicine, Vol. 16, Issue 1, pp. 325, (2016) (PubMed).: "Metronomic Doses of Temozolomide Enhance the Efficacy of Carbon Nanotube CpG Immunotherapy in an Invasive Glioma Model." in: PLoS ONE, Vol. 11, Issue 2, pp. e0148139, (2016) (PubMed).
: "Optimizations of siRNA design for the activation of gene transcription by targeting the TATA-box motif." in: PLoS ONE, Vol. 9, Issue 9, pp. e108253, (2014) (PubMed).
: "LRIG1 inhibits STAT3-dependent inflammation to maintain corneal homeostasis." in: The Journal of clinical investigation, Vol. 124, Issue 1, pp. 385-97, (2014) (PubMed).
: "Down regulation of T cell receptor expression in COPD pulmonary CD8 cells." in: PLoS ONE, Vol. 8, Issue 8, pp. e71629, (2013) (PubMed).
: "Regulatory T-cells and cAMP suppress effector T-cells independently of PKA-CREM/ICER: a potential role for Epac." in: The Biochemical journal, Vol. 456, Issue 3, pp. 463-73, (2013) (PubMed).
: "TGF-β promotes immune responses in the presence of mesenchymal stem cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 192, Issue 1, pp. 103-9, (2013) (PubMed).
: "Harnessing oncolytic virus-mediated antitumor immunity in an infected cell vaccine." in: Molecular therapy : the journal of the American Society of Gene Therapy, Vol. 20, Issue 9, pp. 1791-9, (2012) (PubMed).
: "Developmental heterogeneity in DNA packaging patterns influences T-cell activation and transmigration." in: PLoS ONE, Vol. 7, Issue 9, pp. e43718, (2012) (PubMed).
: "Naive and activated T cells display differential responsiveness to TL1A that affects Th17 generation, maintenance, and proliferation." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 25, Issue 1, pp. 409-19, (2011) (PubMed).
Synonyms and alternative names related to CD247
CD247 molecule (CD247), CD247 antigen (Cd247), CD3zeta-2 (cd3z), CD3zeta-1 (cd3z), CD247 molecule (cd247), Cd247 molecule (Cd247), 4930549J05Rik, A430104F18Rik, AW552088, Cd3, Cd3-eta, CD3-ZETA, Cd3-zeta, CD3H, Cd3h, CD3Q, CD3Z, Cd3z, Cd3zeta, CD247, LOC100136514, LOC100136549, LOC100305023, T3Z, T3z, Tcrk, TCRZ, Tcrz, TCRzetaProtein level used designations for CD247
- CD247 antigen, zeta subunit
- CD3Z antigen, zeta polypeptide (TiT3 complex)
- CD3zeta chain
- T-cell antigen receptor complex, zeta subunit of CD3
- T-cell receptor T3 zeta chain
- T-cell surface glycoprotein CD3 zeta chain
- TCR zeta chain
- CD3 antigen, zeta polypeptide
- CD3-zeta/eta
- T-cell receptor T3 eta chain
- CD3 zeta
- CD3zeta-2
- CD3zeta-1
- CD247 molecule
- cd3zeta
- CD247 antigen
- T-cell receptor CD3 subunit zeta
- T-cell receptor CD3, subunit zeta
- CD3 zeta chain
- CD3 Zeta chain
- antigen CD3Z, zeta polypeptide
- T-cell receptor zeta chain
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