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CD226 Products

(CD226)
This gene encodes a glycoprotein expressed on the surface of NK cells, platelets, monocytes and a subset of T cells. It is a member of the Ig-superfamily containing 2 Ig-like domains of the V-set. The protein mediates cellular adhesion of platelets and megakaryocytic cells to vascular endothelial cells. The protein also plays a role in megakaryocytic cell maturation. [provided by RefSeq, Jul 2008].

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Featured CD226 Categories

CD226 Antibodies

High quality antibodies with extensive validation data.

CD226 ELISA Kits

Reliable ELISA kits for a wide range of species.

CD226 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended CD226 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (3)
Cat. No. ABIN7147143
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Monkey, Mouse
Application WB, ELISA, IHC, IF
Validations
  • (3)
Cat. No. ABIN3184330
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, FACS, IHC, ICC, Neut
Validations
  • (3)
Cat. No. ABIN5684118
Quantity 100 μL
Datasheet Datasheet

Recommended CD226 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6954500
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN2702960
Quantity 96 tests
Datasheet Datasheet
Reactivity Human, Mouse
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN1380380
Quantity 2 x 96 tests
Datasheet Datasheet

Recommended CD226 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (5)
Cat. No. ABIN7274457
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7274455
Quantity 100 μg
Datasheet Datasheet
Reactivity Cynomolgus
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7274454
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our CD226 products

Skitek, Jerin: "Proenkefalin A and protachykinin in ischemic neurological complications after cardiac surgery." in: Medicinski glasnik : official publication of the Medical Association of Zenica-Doboj Canton, Bosnia and Herzegovina, Vol. 13, Issue 1, pp. 8-13, (2017) (PubMed).

Boieri, Ulvmoen, Sudworth, Lendrem, Collin, Dickinson, Kveberg, Inngjerdingen: "IL-12, IL-15, and IL-18 pre-activated NK cells target resistant T cell acute lymphoblastic leukemia and delay leukemia development in vivo." in: Oncoimmunology, Vol. 6, Issue 3, pp. e1274478, (2017) (PubMed).

Mikulak, Bozzo, Roberto, Pontarini, Tentorio, Hudspeth, Lugli, Mavilio: "Dopamine inhibits the effector functions of activated NK cells via the upregulation of the D5 receptor." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 193, Issue 6, pp. 2792-800, (2014) (PubMed).

Liu, Qian, Chen, Xu, Gao, Zhang, Zhang, Qi, Gao, Yan: "Crystal structure of cell adhesion molecule nectin-2/CD112 and its binding to immune receptor DNAM-1/CD226." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 188, Issue 11, pp. 5511-20, (2012) (PubMed).

Magnani, Alberigo, Bacchetta, Serafini, Andreani, Roncarolo, Gregori: "Killing of myeloid APCs via HLA class I, CD2 and CD226 defines a novel mechanism of suppression by human Tr1 cells." in: European journal of immunology, Vol. 41, Issue 6, pp. 1652-62, (2011) (PubMed).

Brunetta, Fogli, Varchetta, Bozzo, Hudspeth, Marcenaro, Moretta, Mavilio: "The decreased expression of Siglec-7 represents an early marker of dysfunctional natural killer-cell subsets associated with high levels of HIV-1 viremia." in: Blood, Vol. 114, Issue 18, pp. 3822-30, (2009) (PubMed).

Kojima, Kanada, Shimizu, Kasama, Shibuya, Nakauchi, Nagasawa, Shibuya: "CD226 mediates platelet and megakaryocytic cell adhesion to vascular endothelial cells." in: The Journal of biological chemistry, Vol. 278, Issue 38, pp. 36748-53, (2003) (PubMed).

Shibuya, Campbell, Hannum, Yssel, Franz-Bacon, McClanahan, Kitamura, Nicholl, Sutherland, Lanier, Phillips: "DNAM-1, a novel adhesion molecule involved in the cytolytic function of T lymphocytes." in: Immunity, Vol. 4, Issue 6, pp. 573-81, (1996) (PubMed).

Synonyms and alternative names related to CD226

CD226 molecule (CD226), CD226 molecule (cd226), CD226 antigen (Cd226), CD226 molecule (Cd226), BC051526, CD226, cd226, DNAM-1, DNAM1, Pta1, PTA1, TLiSA1, zgc:158817

Protein level used designations for CD226

  • CD226 antigen
  • CD226 molecule
  • platelet and T cell activation antigen 1
  • platelet and T-cell activation antigen 1
  • DNAX accessory molecule 1
  • DNAX accessory molecule-1
  • T lineage-specific activation antigen 1 antigen
  • adhesion glycoprotein
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