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CD207 Products

(CD207 Molecule, Langerin (CD207))

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The protein encoded by this gene is expressed only in Langerhans cells which are immature dendritic cells of the epidermis and mucosa. It is localized in the Birbeck granules, organelles present in the cytoplasm of Langerhans cells and consisting of superimposed and zippered membranes. It is a C-type lectin with mannose binding specificity, and it has been proposed that mannose binding by this protein leads to internalization of antigen into Birbeck granules and providing access to a nonclassical antigen-processing pathway. Mutations in this gene result in Birbeck granules deficiency or loss of sugar binding activity. [provided by RefSeq, Aug 2010].

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Featured CD207 Categories

CD207 Antibodies

High quality antibodies with extensive validation data.

CD207 ELISA Kits

Reliable ELISA kits for a wide range of species.

CD207 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended CD207 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC, FACS, ICC
Validations
  • (7)
Cat. No. ABIN7193631
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, FACS
Validations
  • (4)
Cat. No. ABIN5611331
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Non-Human Primate
Application ELISA, FACS, IHC (fro), ICC
Validations
  • (3)
Cat. No. ABIN7505884
Quantity 0.1 mg
Datasheet Datasheet

Recommended CD207 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN1569037
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN4883601
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Semi-Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6385895
Quantity 96 tests
Datasheet Datasheet

Recommended CD207 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1348571
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Human Cells
Validations
Cat. No. ABIN7319643
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN5623935
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our CD207 products

Tanei, Hasegawa et al.: "Immunohistopathological Analysis of Immunoglobulin E-Positive Epidermal Dendritic Cells with House Dust Mite Antigens in Naturally Occurring Skin Lesions of Adult and Elderly Patients with Atopic ..." in: Dermatopathology (Basel, Switzerland), Vol. 8, Issue 3, pp. 426-441, (2021) (PubMed).

Yasuda, Ura, Taniguchi, Yoshida: "Intradermal Delivery of Antigens Enhances Specific IgG and Diminishes IgE Production: Potential Use for Vaccination and Allergy Immunotherapy." in: PLoS ONE, Vol. 11, Issue 12, pp. e0167952, (2016) (PubMed).

De Jesus, Ostroff, Levitz, Bartling, Mantis: "A population of Langerin-positive dendritic cells in murine Peyer's patches involved in sampling β-glucan microparticles." in: PLoS ONE, Vol. 9, Issue 3, pp. e91002, (2014) (PubMed).

Gerber, Münst, Schlapbach, Shafighi, Kiermeir, Hüsler, Hunger: "High expression of FOXP3 in primary melanoma is associated with tumour progression." in: The British journal of dermatology, Vol. 170, Issue 1, pp. 103-9, (2014) (PubMed).

Elnekave, Furmanov, Shaul, Capucha, Eli-Berchoer, Zelentsova, Clausen, Hovav: "Second-generation Langerhans cells originating from epidermal precursors are essential for CD8+ T cell priming." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 192, Issue 4, pp. 1395-403, (2014) (PubMed).

Flacher, Tripp, Mairhofer, Steinman, Stoitzner, Idoyaga, Romani: "Murine Langerin+ dermal dendritic cells prime CD8+ T cells while Langerhans cells induce cross-tolerance." in: EMBO molecular medicine, Vol. 6, Issue 9, pp. 1191-204, (2014) (PubMed).

Sparber, Tripp, Komenda, Scheffler, Clausen, Huber, Romani, Stoitzner: "The late endosomal adaptor molecule p14 (LAMTOR2) regulates TGFβ1-mediated homeostasis of Langerhans cells." in: The Journal of investigative dermatology, Vol. 135, Issue 1, pp. 119-29, (2014) (PubMed).

Voisin, Mairhofer, Chen, Stoitzner, Mueller, Flacher: "Anatomical distribution analysis reveals lack of Langerin+ dermal dendritic cells in footpads and tail of C57BL/6 mice." in: Experimental dermatology, Vol. 23, Issue 5, pp. 354-6, (2014) (PubMed).

Bonetti, Bacci, Santosuosso, Mazzanti, Aldinucci, Ballerini, Guasti, Calosi, Bosi, Romagnoli: "Rosiglitazone promotes the differentiation of Langerhans cells and inhibits that of other dendritic cell types from CD133 positive hematopoietic precursors." in: Histology and histopathology, Vol. 29, Issue 3, pp. 323-32, (2014) (PubMed).

Larbi, Mitjavila-Garcia, Flamant, Valogne, Clay, Usunier, lHomme, Féraud, Casal, Gobbo, Divers, Chapel, Turhan, Bennaceur-Griscelli, Haddad: "Generation of multipotent early lymphoid progenitors from human embryonic stem cells." in: Stem cells and development, Vol. 23, Issue 24, pp. 2983-95, (2014) (PubMed).

Synonyms and alternative names related to CD207

CD207 molecule (CD207), CD207 antigen (Cd207), CD207 molecule (Cd207), CD207, CLEC4K, RGD1565913

Protein level used designations for CD207

  • CD207 molecule, langerin
  • CD207 antigen, langerin
  • C-type lectin domain family 4 member K
  • Langerhans cell specific c-type lectin
  • langerin
  • C-type lectin domain family 4, member K
  • CD 207 antigen
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