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CD2 Products

(CD2)

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CD2 is a surface antigen of the human T-lymphocyte lineage that is expressed on all peripheral blood T cells (summarized by Sewell et al., 1986 [PubMed 3490670]). It is one of the earliest T-cell markers, being present on more than 95% of thymocytes\; it is also found on some natural killer cells but not on B lymphocytes. Monoclonal antibodies directed against CD2 inhibit the formation of rosettes with sheep erythrocytes, indicating that CD2 is the erythrocyte receptor or is closely associated with it.[supplied by OMIM, Jul 2010].

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Featured CD2 Categories

CD2 Antibodies

High quality antibodies with extensive validation data.

CD2 ELISA Kits

Reliable ELISA kits for a wide range of species.

CD2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended CD2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application FACS, WB, ELISA, IHC
Validations
  • (8)
Cat. No. ABIN5542296
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application FACS, WB, ELISA, IHC
Validations
  • (7)
Cat. No. ABIN5542297
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC (p)
Validations
  • (4)
Cat. No. ABIN3187772
Quantity 100 μL
Datasheet Datasheet

Recommended CD2 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6965547
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN4882144
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6730102
Quantity 96 tests
Datasheet Datasheet

Recommended CD2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (4)
Cat. No. ABIN7274105
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7274109
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7122195
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our CD2 products

Amantini, Farfariello, Cardinali, Morelli, Marinelli, Nabissi, Santoni, Bonfili, Cecarini, Eleuteri, Santoni: "The TRPV1 ion channel regulates thymocyte differentiation by modulating autophagy and proteasome activity." in: Oncotarget, Vol. 8, Issue 53, pp. 90766-90780, (2017) (PubMed).

Moutinho, Martinez-Cardús, Santos, Navarro-Pérez, Martínez-Balibrea, Musulen, Carmona, Sartore-Bianchi, Cassingena, Siena, Elez, Tabernero, Salazar, Abad, Esteller: "Epigenetic inactivation of the BRCA1 interactor SRBC and resistance to oxaliplatin in colorectal cancer." in: Journal of the National Cancer Institute, Vol. 106, Issue 1, pp. djt322, (2014) (PubMed).

Zhang, Dai, Li, Zhuang: "Tracking proliferative history in lymphocyte development with cre-mediated sister chromatid recombination." in: PLoS genetics, Vol. 9, Issue 10, pp. e1003887, (2013) (PubMed).

Kashiwakura, Sakurai, Kanno, Hashiguchi, Kobayashi, Kurosu, Tokudome, Kobata, Kojima: "CD2-mediated regulation of peripheral CD4(+)  CD25(+) regulatory T-cell apoptosis accompanied by down-regulation of Bim." in: Immunology, Vol. 139, Issue 1, pp. 48-60, (2013) (PubMed).

Baker, Rohman, Hinley, Stahlschmidt, Cameron, Southgate: "Cellular integration and vascularisation promoted by a resorbable, particulate-leached, cross-linked poly(?-caprolactone) scaffold." in: Macromolecular bioscience, Vol. 11, Issue 5, pp. 618-27, (2011) (PubMed).

Serra, Horenstein, Vaisitti, Brusa, Rossi, Laurenti, DArena, Coscia, Tripodo, Inghirami, Robson, Gaidano, Malavasi, Deaglio: "CD73-generated extracellular adenosine in chronic lymphocytic leukemia creates local conditions counteracting drug-induced cell death." in: Blood, Vol. 118, Issue 23, pp. 6141-52, (2011) (PubMed).

Platt, Sponseller, Chiang, Roth: "Cell-mediated immunity evaluation in foals infected with virulent equine herpesvirus-1 by multi-parameter flow cytometry." in: Veterinary immunology and immunopathology, Vol. 135, Issue 3-4, pp. 275-81, (2010) (PubMed).

Jiang, Peterlin: "Differential chromatin looping regulates CD4 expression in immature thymocytes." in: Molecular and cellular biology, Vol. 28, Issue 3, pp. 907-12, (2008) (PubMed).

Piriou-Guzylack, Salmon: "Membrane markers of the immune cells in swine: an update." in: Veterinary research, Vol. 39, Issue 6, pp. 54, (2008) (PubMed).

Espagnolle, Depoil, Zaru, Demeur, Champagne, Guiraud, Valitutti: "CD2 and TCR synergize for the activation of phospholipase Cgamma1/calcium pathway at the immunological synapse." in: International immunology, Vol. 19, Issue 3, pp. 239-48, (2007) (PubMed).

Synonyms and alternative names related to CD2

CD2 molecule (CD2), CD2 antigen (Cd2), Cd2 molecule (Cd2), CD2, CD2R, LFA-2, LFA2, Ly-37, Ly37, OX-34, OX34, SRBC, T11

Protein level used designations for CD2

  • CD2 antigen (p50), sheep red blood cell receptor
  • T-cell surface antigen CD2
  • cluster of differentiation 2
  • CD2 antigen
  • CD2 molecule
  • LFA-3 receptor
  • T-cell surface antigen T11/Leu-5
  • lymphocyte antigen 37
  • erythrocyte receptor
  • lymphocyte-function antigen-2
  • rosette receptor
  • OX-34 antigen
  • OX-45 surface antigen homolog to human T lymphocyte CD2 antigen
  • T-lymphocyte surface antigen precursor CD2
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