CD1d Products
(CD1d Molecule (CD1D))
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This gene encodes a divergent member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail. [provided by RefSeq, Jul 2008].
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Featured CD1d Categories
CD1d Antibodies
High quality antibodies with extensive validation data.
CD1d Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended CD1d Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (3)
Cat. No.
ABIN7440008
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Rat
Application
WB, IHC, IP, ICC
Validations
- (3)
Cat. No.
ABIN7440044
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, IHC, IF
Validations
- (3)
Cat. No.
ABIN7257038
Quantity
200 μL
Datasheet
Datasheet
Recommended CD1d Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1348560
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Baculovirus infected Insect Cells
Validations
- (1)
Cat. No.
ABIN7529377
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN7320378
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our CD1d products
: "Vaccination with antigen-transfected, NKT cell ligand-loaded, human cells elicits robust in situ immune responses by dendritic cells." in: Cancer research, Vol. 73, Issue 1, pp. 62-73, (2013) (PubMed).: "CD1d-dependent, iNKT-cell cytotoxicity against keratinocytes in allergic contact dermatitis." in: Experimental dermatology, Vol. 21, Issue 12, pp. 915-20, (2012) (PubMed).
: "Deficiency of antigen-presenting cell invariant chain reduces atherosclerosis in mice." in: Circulation, Vol. 122, Issue 8, pp. 808-20, (2010) (PubMed).
: "CD1d expression in paneth cells and rat exocrine pancreas revealed by novel monoclonal antibodies which differentially affect NKT cell activation." in: PLoS ONE, Vol. 5, Issue 9, (2010) (PubMed).
: "A central role for transcription factor C/EBP-beta in regulating CD1d gene expression in human keratinocytes." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 183, Issue 3, pp. 1657-66, (2009) (PubMed).
: "Regulation of multiple myeloma survival and progression by CD1d." in: Blood, Vol. 113, Issue 11, pp. 2498-507, (2009) (PubMed).
: "Human CD1-restricted T cell recognition of lipids from pollens." in: The Journal of experimental medicine, Vol. 202, Issue 2, pp. 295-308, (2005) (PubMed).
: "Glycolipid antigen processing for presentation by CD1d molecules." in: Science (New York, N.Y.), Vol. 291, Issue 5504, pp. 664-7, (2001) (PubMed).
: "Overexpression of CD1d by keratinocytes in psoriasis and CD1d-dependent IFN-gamma production by NK-T cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 165, Issue 7, pp. 4076-85, (2000) (PubMed).
: "Lipid antigen presentation in the immune system: lessons learned from CD1d knockout mice." in: Immunological reviews, Vol. 169, pp. 31-44, (1999) (PubMed).
Synonyms and alternative names related to CD1d
CD1d molecule (CD1D), CD1D antigen, d polypeptide (CD1D), CD1A, CD1D, CD1D1, R3Protein level used designations for CD1d
- CD1D antigen, d polypeptide
- HMC class I antigen-like glycoprotein CD1D
- R3G1
- T-cell surface glycoprotein CD1d
- antigen-presenting glycoprotein CD1d
- differentiation antigen CD1-alpha-3
- thymocyte antigen CD1D
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