CD1b Products
(CD1b (CD1B))
Categories
This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to late endosomes and lysosomes via a tyrosine-based motif in the cytoplasmic tail, and requires vesicular acidification to bind lipid antigens. [provided by RefSeq, Jul 2008].
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Featured CD1b Categories
CD1b Antibodies
High quality antibodies with extensive validation data.
CD1b Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended CD1b Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
FACS, IP, IHC (fro), IHC (p)
Validations
- (3)
- (4)
Cat. No.
ABIN1981866
Quantity
0.1 mg
Datasheet
Datasheet
Reactivity
Human
Application
FACS, ELISA
Validations
- (4)
Cat. No.
ABIN5611268
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
FACS, ELISA
Validations
- (4)
Cat. No.
ABIN5611269
Quantity
100 μL
Datasheet
Datasheet
Recommended CD1b Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7122194
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1348554
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1348556
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our CD1b products
: "Identification of changes in dendritic cell subsets that correlate with disease severity in dengue infection." in: PLoS ONE, Vol. 13, Issue 7, pp. e0200564, (2018) (PubMed).: "Summary of the animal homologue section of HLDA8." in: Veterinary immunology and immunopathology, Vol. 119, Issue 1-2, pp. 2-13, (2007) (PubMed).
: "Impaired expression of perforin and granulysin in CD8+ T cells at the site of infection in human chronic pulmonary tuberculosis." in: Infection and immunity, Vol. 75, Issue 11, pp. 5210-22, (2007) (PubMed).
: "Lactoferrin prevents dendritic cell-mediated human immunodeficiency virus type 1 transmission by blocking the DC-SIGN--gp120 interaction." in: Journal of virology, Vol. 79, Issue 5, pp. 3009-15, (2005) (PubMed).
: "Filaria-induced immune evasion: suppression by the infective stage of Brugia malayi at the earliest host-parasite interface." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 172, Issue 10, pp. 6229-38, (2004) (PubMed).
: "Human macrophage lectin specific for galactose/N-acetylgalactosamine is a marker for cells at an intermediate stage in their differentiation from monocytes into macrophages." in: International immunology, Vol. 14, Issue 6, pp. 545-54, (2002) (PubMed).
: "The in vivo development of human T cells from CD34(+) cells in the murine thymic environment." in: International immunology, Vol. 14, Issue 10, pp. 1113-24, (2002) (PubMed).
: "The maturation of dendritic cells results in postintegration inhibition of HIV-1 replication." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 166, Issue 6, pp. 3780-8, (2001) (PubMed).
: "The A' and F' pockets of human CD1b are both required for optimal presentation of lipid antigens to T cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 166, Issue 4, pp. 2562-70, (2001) (PubMed).
: "Influence of Mycobacterium bovis bacillus Calmette Guérin on in vitro induction of CD1 molecules in human adherent mononuclear cells." in: Infection and immunity, Vol. 69, Issue 12, pp. 7461-70, (2001) (PubMed).
Synonyms and alternative names related to CD1b
CD1b molecule (CD1B), T-cell surface glycoprotein CD1b-3 (LOC443423), CD1b1 molecule (CD1B1), T-cell surface glycoprotein CD1b1 (LOC100720602), CD1, CD1-b, CD1A, CD1B, CD1B3, R1Protein level used designations for CD1b
- CD1B antigen, b polypeptide
- T-cell surface glycoprotein CD1b
- cortical thymocyte antigen CD1B
- differentiation antigen CD1-alpha-3
- CD1b3
- CD1b molecule
- T-cell surface glycoprotein CD1b-3
- CD1b antigen
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