CD1a Products
(CD1a)
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This gene encodes a member of the CD1 family of transmembrane glycoproteins, which are structurally related to the major histocompatibility complex (MHC) proteins and form heterodimers with beta-2-microglobulin. The CD1 proteins mediate the presentation of primarily lipid and glycolipid antigens of self or microbial origin to T cells. The human genome contains five CD1 family genes organized in a cluster on chromosome 1. The CD1 family members are thought to differ in their cellular localization and specificity for particular lipid ligands. The protein encoded by this gene localizes to the plasma membrane and to recycling vesicles of the early endocytic system. Alternatively spliced transcript variants have been observed, but their biological validity has not been determined. [provided by RefSeq, Jul 2008].
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Featured CD1a Categories
CD1a Antibodies
High quality antibodies with extensive validation data.
CD1a Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended CD1a Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
IHC, WB, ELISA, ICC
Validations
- (2)
- (5)
Cat. No.
ABIN969017
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
FACS, ELISA, IHC (p), IHC (fro), IF (p), IF (cc)
Validations
- (4)
Cat. No.
ABIN704096
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
FACS
Validations
- (9)
- (3)
Cat. No.
ABIN94019
Quantity
100 tests
Datasheet
Datasheet
Recommended CD1a Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (2)
Cat. No.
ABIN7274279
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
- (1)
Cat. No.
ABIN1348552
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
Cat. No.
ABIN6964179
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our CD1a products
: "Secretome analysis of human articular chondrocytes unravels catabolic effects of nicotine on the joint." in: Proteomics. Clinical applications, Vol. 10, Issue 6, pp. 671-80, (2017) (PubMed).: "The necrosome promotes pancreatic oncogenesis via CXCL1 and Mincle-induced immune suppression." in: Nature, Vol. 532, Issue 7598, pp. 245-9, (2016) (PubMed).
: "Variable expression levels of keratin and vimentin reveal differential EMT status of circulating tumor cells and correlation with clinical characteristics and outcome of patients with metastatic ..." in: BMC cancer, Vol. 15, pp. 399, (2016) (PubMed).
: "Administration of granulocyte colony-stimulating factor with radiotherapy promotes tumor growth by stimulating vascularization in tumor-bearing mice." in: Oncology reports, Vol. 34, Issue 1, pp. 147-54, (2016) (PubMed).
: "TAS-116, a highly selective inhibitor of heat shock protein 90α and β, demonstrates potent antitumor activity and minimal ocular toxicity in preclinical models." in: Molecular cancer therapeutics, Vol. 14, Issue 1, pp. 14-22, (2015) (PubMed).
: "Suppression of TDO-mediated tryptophan catabolism in glioblastoma cells by a steroid-responsive FKBP52-dependent pathway." in: Glia, Vol. 63, Issue 1, pp. 78-90, (2015) (PubMed).
: "Plakophilin 3 mediates Rap1-dependent desmosome assembly and adherens junction maturation." in: Molecular biology of the cell, Vol. 25, Issue 23, pp. 3749-64, (2015) (PubMed).
: "Neonatal surgical castration of male pigs reduces thymic growth but has moderate consequences on thymocytes." in: Journal of animal science, Vol. 92, Issue 6, pp. 2415-21, (2014) (PubMed).
: "Characterization of the adaptive immune response following immunization in pregnant sows (Sus scrofa) kept in two different housing systems." in: Journal of animal science, Vol. 92, Issue 8, pp. 3388-97, (2014) (PubMed).
: "Adeno-associated virus Rep represses the human integration site promoter by two pathways that are similar to those required for the regulation of the viral p5 promoter." in: Journal of virology, Vol. 88, Issue 15, pp. 8227-41, (2014) (PubMed).
Synonyms and alternative names related to CD1a
CD1a molecule (CD1A), CD1 antigen (CD1.1), T-cell surface glycoprotein CD1a (LOC100156095), T-cell surface glycoprotein CD1a (LOC101111409), CD1, CD1A, FCB6, HTA1, R4, T6Protein level used designations for CD1a
- CD1A antigen, a polypeptide
- T-cell surface antigen T6/Leu-6
- T-cell surface glycoprotein CD1a
- cluster of differentiation 1 A
- cortical thymocyte antigen CD1A
- differentiation antigen CD1-alpha-3
- epidermal dendritic cell marker CD1a
- hTa1 thymocyte antigen
- CD1a molecule
- LOW QUALITY PROTEIN: T-cell surface glycoprotein CD1a
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