CD137 Products
(Tumor Necrosis Factor Receptor Superfamily, Member 9 (TNFRSF9))
Categories
The protein encoded by this gene is a member of the TNF-receptor superfamily. This receptor contributes to the clonal expansion, survival, and development of T cells. It can also induce proliferation in peripheral monocytes, enhance T cell apoptosis induced by TCR/CD3 triggered activation, and regulate CD28 co-stimulation to promote Th1 cell responses. The expression of this receptor is induced by lymphocyte activation. TRAF adaptor proteins have been shown to bind to this receptor and transduce the signals leading to activation of NF-kappaB. [provided by RefSeq, Jul 2008].
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Featured CD137 Categories
CD137 Antibodies
High quality antibodies with extensive validation data.
CD137 ELISA Kits
Reliable ELISA kits for a wide range of species.
CD137 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended CD137 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
ELISA, FACS, WB, IHC (p)
Validations
- (2)
- (1)
- (1)
Cat. No.
ABIN740445
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, FACS, WB, IHC, IF, IHC (p), Coat, StM
Validations
- (8)
Cat. No.
ABIN6939788
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, FACS, WB
Validations
- (5)
Cat. No.
ABIN7193622
Quantity
100 μL
Datasheet
Datasheet
Recommended CD137 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6970994
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6960300
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN924754
Quantity
96 tests
Datasheet
Datasheet
Recommended CD137 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (4)
Cat. No.
ABIN7273924
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (4)
Cat. No.
ABIN7273922
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (4)
Cat. No.
ABIN7273923
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our CD137 products
: "4-1BB Signaling Promotes Alveolar Macrophages-Mediated Pro-Fibrotic Responses and Crystalline Silica-Induced Pulmonary Fibrosis in Mice." in: Frontiers in immunology, Vol. 9, pp. 1848, (2019) (PubMed).: "Anti-CD137 monoclonal antibody enhances trastuzumab-induced, natural killer cell-mediated cytotoxicity against pancreatic cancer cell lines with low human epidermal growth factor-like receptor 2 ..." in: PLoS ONE, Vol. 13, Issue 12, pp. e0200664, (2018) (PubMed).
: "Decreased beige adipocyte number and mitochondrial respiration coincide with increased histone methyl transferase (G9a) and reduced FGF21 gene expression in Sprague-Dawley rats fed prenatal low ..." in: The Journal of nutritional biochemistry, Vol. 31, pp. 113-21, (2016) (PubMed).
: "Isoproterenol Increases Uncoupling, Glycolysis, and Markers of Beiging in Mature 3T3-L1 Adipocytes." in: PLoS ONE, Vol. 10, Issue 9, pp. e0138344, (2016) (PubMed).
: "Targeting peripheral blood pro-inflammatory cytotoxic lymphocytes by inhibiting CD137 expression: novel potential treatment for COPD." in: BMC pulmonary medicine, Vol. 14, pp. 85, (2015) (PubMed).
: "Depletion of white adipocyte progenitors induces beige adipocyte differentiation and suppresses obesity development." in: Cell death and differentiation, (2014) (PubMed).
: "Human and mouse CD137 have predominantly different binding CRDs to their respective ligands." in: PLoS ONE, Vol. 9, Issue 1, pp. e86337, (2014) (PubMed).
: "SAHA/Vorinostat induces the expression of the CD137 receptor/ligand system and enhances apoptosis mediated by soluble CD137 receptor in a human breast cancer cell line." in: International journal of oncology, Vol. 41, Issue 4, pp. 1486-94, (2013) (PubMed).
: "T cell costimulation with anti-CD137 monoclonal antibodies is mediated by K63-polyubiquitin-dependent signals from endosomes." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 190, Issue 12, pp. 6694-706, (2013) (PubMed).
: "CD137 differentially regulates innate and adaptive immunity against Mycobacterium tuberculosis." in: Immunology and cell biology, Vol. 90, Issue 4, pp. 449-56, (2012) (PubMed).
Synonyms and alternative names related to CD137
tumor necrosis factor receptor superfamily member 9 (TNFRSF9), TNF receptor superfamily member 9 (TNFRSF9), tumor necrosis factor receptor superfamily, member 9a (tnfrsf9a), tumor necrosis factor receptor superfamily, member 9 (Tnfrsf9), 4-1BB, A930040I11Rik, AA408498, AI325004, CD137, Cd137, CDw137, ILA, Ly63, TNFRSF9, zgc:136557Protein level used designations for CD137
- tumor necrosis factor receptor superfamily, member 9
- tumor necrosis factor receptor superfamily member 9
- 4-1BB ligand receptor
- CD137 antigen
- T cell antigen ILA
- T-cell antigen 4-1BB homolog
- T-cell antigen ILA
- homolog of mouse 4-1BB
- induced by lymphocyte activation (ILA)
- interleukin-activated receptor, homolog of mouse Ly63
- receptor protein 4-1BB
- T-cell antigen 4-1BB
- secreted CD137 antigen
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