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CD11c Products

(Integrin, alpha X (Complement Component 3 Receptor 4 Subunit) (ITGAX))

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This gene encodes the integrin alpha X chain protein. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This protein combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as inactivated-C3b (iC3b) receptor 4 (CR4). The alpha X beta 2 complex seems to overlap the properties of the alpha M beta 2 integrin in the adherence of neutrophils and monocytes to stimulated endothelium cells, and in the phagocytosis of complement coated particles. [provided by RefSeq, Jul 2008].

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Featured CD11c Categories

CD11c Antibodies

High quality antibodies with extensive validation data.

CD11c Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended CD11c Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Monkey
Application FACS
Validations
  • (5)
  • (4)
Cat. No. ABIN302018
Quantity 100 tests
Datasheet Datasheet
Reactivity Human
Application FACS, WB, IF, IHC (p)
Validations
  • (1)
  • (4)
Cat. No. ABIN390974
Quantity 400 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application IHC, WB, IF
Validations
  • (5)
Cat. No. ABIN7249394
Quantity 200 μL
Datasheet Datasheet

Recommended CD11c ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6226842
Quantity 96 tests
Datasheet Datasheet

Recommended CD11c Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7123475
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1308185
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7415731
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our CD11c products

Meng, Li, Ye, Yin, Sun, Liao, Li, Deng, Liu, Yu, Wu, Zhou, Shen: "MicroRNA-148a facilitates inflammatory dendritic cell differentiation and autoimmunity by targeting MAFB." in: JCI insight, Vol. 5, Issue 8, (2021) (PubMed).

Zhu, Feng, Shu, Gao, Wu, Du, Li, Wang, Chen, Li, Luo, Wu: "In situ transplantation of adipose-derived stem cells via photoactivation improves glucose metabolism in obese mice." in: Stem cell research & therapy, Vol. 12, Issue 1, pp. 408, (2021) (PubMed).

He, Li, Xie, Zhao: "Long-term inhibition of dipeptidyl-peptidase 4 reduces islet infiltration and downregulates IL-1β and IL-12 in NOD mice." in: International immunopharmacology, Vol. 88, pp. 106945, (2021) (PubMed).

Garcia-Agudo, Janova, Sendler, Arinrad, Steixner, Hassouna, Balmuth, Ronnenberg, Schopf, van der Flier, Begemann, Martens, Weber, Boretius, Nave, Ehrenreich: "Genetically induced brain inflammation by Cnp deletion transiently benefits from microglia depletion." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 33, Issue 7, pp. 8634-8647, (2019) (PubMed).

Oanh, Park, Cho: "Mitochondria elongation is mediated through SIRT1-mediated MFN1 stabilization." in: Cellular signalling, Vol. 38, pp. 67-75, (2018) (PubMed).

Medler, Murugan, Horton, Kumar, Cotechini, Forsyth, Leyshock, Leitenberger, Kulesz-Martin, Margolin, Werb, Coussens: "Complement C5a Fosters Squamous Carcinogenesis and Limits T Cell Response to Chemotherapy." in: Cancer cell, Vol. 34, Issue 4, pp. 561-578.e6, (2018) (PubMed).

Sagar, Singh, Ginwala, Huang, Philip, Nagarkatti, Nagarkatti, Neumann, Ruland, Andrews, Ramirez, Khan, Jain: "Antibody blockade of CLEC12A delays EAE onset and attenuates disease severity by impairing myeloid cell CNS infiltration and restoring positive immunity." in: Scientific reports, Vol. 7, Issue 1, pp. 2707, (2017) (PubMed).

Keren-Shaul, Spinrad, Weiner, Matcovitch-Natan, Dvir-Szternfeld, Ulland, David, Baruch, Lara-Astaiso, Toth, Itzkovitz, Colonna, Schwartz, Amit: "A Unique Microglia Type Associated with Restricting Development of Alzheimer's Disease." in: Cell, Vol. 169, Issue 7, pp. 1276-1290.e17, (2017) (PubMed).

Sprokholt, Heineke, Kaptein, van Hamme, Geijtenbeek: "DCs facilitate B cell responses against microbial DNA via DC-SIGN." in: PLoS ONE, Vol. 12, Issue 10, pp. e0185580, (2017) (PubMed).

Srivastava, Trivedi, Concha-Benavente, Gibson, Reeder, Ferrone, Ferris: "CD137 Stimulation Enhances Cetuximab-Induced Natural Killer: Dendritic Cell Priming of Antitumor T-Cell Immunity in Patients with Head and Neck Cancer." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 23, Issue 3, pp. 707-716, (2016) (PubMed).

Synonyms and alternative names related to CD11c

integrin subunit alpha X (ITGAX), integrin subunit alpha X (Itgax), integrin alpha X (Itgax), AI449405, CD11C, Cd11c, Cr4, N418, RGD1561123, SLEB6

Protein level used designations for CD11c

  • CD11 antigen-like family member C
  • integrin alpha-X
  • integrin, alpha X (antigen CD11C (p150), alpha polypeptide)
  • leu M5, alpha subunit
  • leukocyte adhesion glycoprotein p150,95 alpha chain
  • leukocyte adhesion receptor p150,95
  • leukocyte surface antigen p150,95, alpha subunit
  • myeloid membrane antigen, alpha subunit
  • p150 95 integrin alpha chain
  • CD11C (p150) alpha polypeptide
  • complement receptor 4
  • integrin aX
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