CD11b Products
(Integrin alpha M (ITGAM))
Categories
This gene encodes the integrin alpha M chain. Integrins are heterodimeric integral membrane proteins composed of an alpha chain and a beta chain. This I-domain containing alpha integrin combines with the beta 2 chain (ITGB2) to form a leukocyte-specific integrin referred to as macrophage receptor 1 ('Mac-1'), or inactivated-C3b (iC3b) receptor 3 ('CR3'). The alpha M beta 2 integrin is important in the adherence of neutrophils and monocytes to stimulated endothelium, and also in the phagocytosis of complement coated particles. Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009].
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Featured CD11b Categories
CD11b Antibodies
High quality antibodies with extensive validation data.
CD11b ELISA Kits
Reliable ELISA kits for a wide range of species.
CD11b Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended CD11b Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
FACS
Validations
- (4)
- (7)
Cat. No.
ABIN741285
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
FACS, WB, IHC (p)
Validations
- (1)
- (7)
Cat. No.
ABIN654625
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
IHC, WB, IF
Validations
- (1)
- (6)
Cat. No.
ABIN3022180
Quantity
100 μL
Datasheet
Datasheet
Recommended CD11b ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6962968
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6956841
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6956842
Quantity
96 tests
Datasheet
Datasheet
Recommended CD11b Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7123468
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1308181
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
Cat. No.
ABIN6964128
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our CD11b products
: "Necroptosis is active and contributes to intestinal injury in a piglet model with lipopolysaccharide challenge." in: Cell death & disease, Vol. 12, Issue 1, pp. 62, (2021) (PubMed).: "Involvement of kindlin-2 in irisin's protection against ischaemia reperfusion-induced liver injury in high-fat diet-fed mice." in: Journal of cellular and molecular medicine, Vol. 24, Issue 22, pp. 13081-13092, (2021) (PubMed).
: "Targeting herpes simplex virus with CRISPR-Cas9 cures herpetic stromal keratitis in mice." in: Nature biotechnology, Vol. 39, Issue 5, pp. 567-577, (2021) (PubMed).
: "Long-term inhibition of dipeptidyl-peptidase 4 reduces islet infiltration and downregulates IL-1β and IL-12 in NOD mice." in: International immunopharmacology, Vol. 88, pp. 106945, (2021) (PubMed).
: "Loss of natural resistance to schistosome in T cell deficient rat." in: PLoS neglected tropical diseases, Vol. 14, Issue 12, pp. e0008909, (2021) (PubMed).
: "MMI-0100 Ameliorates Dextran Sulfate Sodium-Induced Colitis in Mice through Targeting MK2 Pathway." in: Molecules (Basel, Switzerland), Vol. 24, Issue 15, (2020) (PubMed).
: "Optimization Strategy for Generating Gene-edited Tibet Minipigs by Synchronized Oestrus and Cytoplasmic Microinjection." in: International journal of biological sciences, Vol. 15, Issue 12, pp. 2719-2732, (2020) (PubMed).
: "PR1P ameliorates neurodegeneration through activation of VEGF signaling pathway and remodeling of the extracellular environment." in: Neuropharmacology, Vol. 148, pp. 96-106, (2019) (PubMed).
: "Local Injection of Submicron Particle Docetaxel is Associated with Tumor Eradication, Reduced Systemic Toxicity and an Immunologic Response in Uro-Oncologic Xenografts." in: Cancers, Vol. 11, Issue 4, (2019) (PubMed).
: "Using paracrine effects of Ad-MSCs on keratinocyte cultivation and fabrication of epidermal sheets for improving clinical applications." in: Cell and tissue banking, Vol. 19, Issue 4, pp. 531-547, (2019) (PubMed).
Synonyms and alternative names related to CD11b
integrin subunit alpha M (ITGAM), integrin alpha M (Itgam), integrin subunit alpha M (Itgam), integrin, alpha M (complement component 3 receptor 3 subunit) (ITGAM), integrin alpha-M (LOC100351865), C3bi, Cd11b, CD11B, CD11b/CD18, CR3, CR3A, F730045J24Rik, Ly-40, Mac-1, MAC-1, Mac-1a, MAC1, MAC1A, MO1A, SLEB6Protein level used designations for CD11b
- MAC-1 alpha subunit
- integrin alpha M
- integrin alpha-M
- CD11 antigen-like family member B
- CD11B (p170)
- CR-3 alpha chain
- Mac-1 alpha
- cell surface glycoprotein MAC-1 alpha subunit
- cell surface glycoprotein MAC-1 subunit alpha
- complement component receptor 3 alpha-a
- complement receptor type 3
- leukocyte adhesion receptor MO1
- macrophage antigen alpha
- antigen CD11b (p170)
- macrophage antigen alpha polypeptide
- neutrophil adherence receptor alpha-M subunit
- leukocyte integrin alpha-M chain
- complement receptor 3
- leukocyte integrin alpha M
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