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CCT8 Products

(Chaperonin Containing TCP1, Subunit 8 (Theta) (CCT8))

Categories

Molecular chaperone\; assists the folding of proteins upon ATP hydrolysis. As part of the BBS/CCT complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. Known to play a role, in vitro, in the folding of actin and tubulin (By similarity).

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Featured CCT8 Categories

CCT8 Antibodies

High quality antibodies with extensive validation data.

CCT8 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended CCT8 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet

Application WB
Validations
  • (2)
  • (5)
Cat. No. ABIN2782379
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (4)
Cat. No. ABIN7171428
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, FACS, IHC (p)
Validations
  • (2)
  • (3)
Cat. No. ABIN656431
Quantity 400 μL
Datasheet Datasheet

Recommended CCT8 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1348527
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2713341
Quantity 20 μg
Datasheet Datasheet
Reactivity Encephalitozoon cuniculi
Source Yeast
Validations
Cat. No. ABIN1638249
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our CCT8 products

Yin, Miao, Wu, Wei, Zong, Yang, Chen, Zheng, Zhu, Guo, Li, Chen, Wang, He: "The role of the Chaperonin containing t-complex polypeptide 1, subunit 8 (CCT8) in B-cell non-Hodgkin's lymphoma." in: Leukemia research, Vol. 45, pp. 59-67, (2017) (PubMed).

Qiu, He, Huang, Liu, Sun, Guo, Yuan, Yang, Ban, Fan, Tao, Wang: "Overexpression of CCT8 and its significance for tumor cell proliferation, migration and invasion in glioma." in: Pathology, research and practice, Vol. 211, Issue 10, pp. 717-25, (2016) (PubMed).

Spellman, Ahmed, Dubach, Gardiner: "Expression of trisomic proteins in Down syndrome model systems." in: Gene, Vol. 512, Issue 2, pp. 219-25, (2012) (PubMed).

Neef, Turski, Thiele: "Modulation of heat shock transcription factor 1 as a therapeutic target for small molecule intervention in neurodegenerative disease." in: PLoS biology, Vol. 8, Issue 1, pp. e1000291, (2010) (PubMed).

Hynes, Willison: "Individual subunits of the eukaryotic cytosolic chaperonin mediate interactions with binding sites located on subdomains of beta-actin." in: The Journal of biological chemistry, Vol. 275, Issue 25, pp. 18985-94, (2000) (PubMed).

Llorca, Martín-Benito, Ritco-Vonsovici, Grantham, Hynes, Willison, Carrascosa, Valpuesta: "Eukaryotic chaperonin CCT stabilizes actin and tubulin folding intermediates in open quasi-native conformations." in: The EMBO journal, Vol. 19, Issue 22, pp. 5971-9, (2000) (PubMed).

Suzuki, Yoshitomo-Nakagawa, Maruyama, Suyama, Sugano: "Construction and characterization of a full length-enriched and a 5'-end-enriched cDNA library." in: Gene, Vol. 200, Issue 1-2, pp. 149-56, (1997) (PubMed).

Synonyms and alternative names related to CCT8

chaperonin containing TCP1 subunit 8 (CCT8), chaperonin containing TCP1, subunit 8 (theta) (CCT8), chaperonin containing TCP1 subunit 8 (cct8), chaperonin containing Tcp1, subunit 8 (theta) (Cct8), chaperonin containing TCP1, subunit 8 (theta) (cct8), chaperonin containing TCP1 subunit 8 L homeolog (cct8.L), chaperonin containing TCP1 subunit 8 (Cct8), Chaperonin Containing TCP-1 (cct-8), AI132397, C21orf112, CCT8, Cctq, D21S246, DKFZp469C2223, fa22h09, MGC89698, PRED71, Tcpq, wu:fa22h09, zgc:56059

Protein level used designations for CCT8

  • chaperonin containing TCP1, subunit 8 (theta)
  • T-complex protein 1 subunit theta
  • T-complex protein 1 subunit theta-like
  • CCT-theta
  • T-complex protein 1, theta subunit
  • TCP-1-theta
  • renal carcinoma antigen NY-REN-15
  • chaperonin subunit 8 (theta)
  • bdav
  • bette davis
  • chaperonin subunit 8 theta
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