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CCRL2 Products

(Chemokine (C-C Motif) Receptor-Like 2 (CCRL2))

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This gene encodes a chemokine receptor like protein, which is predicted to be a seven transmembrane protein and most closely related to CCR1. Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. This gene is expressed at high levels in primary neutrophils and primary monocytes, and is further upregulated on neutrophil activation and during monocyte to macrophage differentiation. The function of this gene is unknown. This gene is mapped to the region where the chemokine receptor gene cluster is located. [provided by RefSeq, Jul 2008].

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Featured CCRL2 Categories

CCRL2 Antibodies

High quality antibodies with extensive validation data.

CCRL2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended CCRL2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application IF, IHC
Validations
  • (3)
Cat. No. ABIN7073461
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC
Validations
  • (2)
Cat. No. ABIN7145946
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Rat
Application WB, ELISA, IF, ICC
Validations
  • (2)
Cat. No. ABIN6260564
Quantity 100 μL
Datasheet Datasheet

Recommended CCRL2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7122316
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1348506
Quantity 25 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
Cat. No. ABIN1329957
Quantity 2 μg
Datasheet Datasheet

Latest Publications for our CCRL2 products

Quan, Park, Jin, Kim, Park, Kang et al.: "Sirtuin 3 Activation by Honokiol Decreases Unilateral Ureteral Obstruction-Induced Renal Inflammation and Fibrosis via Regulation of Mitochondrial Dynamics and the Renal NF-κBTGF-β1/Smad Signaling ..." in: International journal of molecular sciences, Vol. 21, Issue 2, (2020) (PubMed).

Kim, Park, Lee, Kim, Park, Kang: "Absence of Sirt3 aggravates cisplatin nephrotoxicity via enhanced renal tubular apoptosis and inflammation." in: Molecular medicine reports, Vol. 18, Issue 4, pp. 3665-3672, (2019) (PubMed).

Nguyễn-Thanh, Kim, Lee, Kim, Park, Kang: "Inhibition of histone deacetylase 1 ameliorates renal tubulointerstitial fibrosis via modulation of inflammation and extracellular matrix gene transcription in mice." in: International journal of molecular medicine, Vol. 41, Issue 1, pp. 95-106, (2018) (PubMed).

Vinci, Bastone, Schiarea, Cappuzzello, Del Prete, Dander, Biondi, DAmico: "Mesenchymal stromal cell-secreted chemerin is a novel immunomodulatory molecule driving the migration of ChemR23-expressing cells." in: Cytotherapy, Vol. 19, Issue 2, pp. 200-210, (2017) (PubMed).

Monnier, Lewén, OHara, Huang, Tu, Butcher, Zabel: "Expression, regulation, and function of atypical chemerin receptor CCRL2 on endothelial cells." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 189, Issue 2, pp. 956-67, (2012) (PubMed).

Leick, Catusse, Follo, Nibbs, Hartmann, Veelken, Burger: "CCL19 is a specific ligand of the constitutively recycling atypical human chemokine receptor CRAM-B." in: Immunology, Vol. 129, Issue 4, pp. 536-46, (2010) (PubMed).

Hartmann, Leick, Ewers, Diefenbacher, Schraufstatter, Honczarenko, Burger: "Human B cells express the orphan chemokine receptor CRAM-A/B in a maturation-stage-dependent and CCL5-modulated manner." in: Immunology, Vol. 125, Issue 2, pp. 252-62, (2008) (PubMed).

Synonyms and alternative names related to CCRL2

C-C motif chemokine receptor like 2 (Ccrl2), C-C motif chemokine receptor like 2 (CCRL2), chemokine (C-C motif) receptor-like 2 (Ccrl2), 1810047I05Rik, ACKR5, Ackr5, CCR11, CCRL2, CKRX, Cmkbr1l2, CRAM, CRAM-A, CRAM-B, E01, HCR, L-CCR

Protein level used designations for CCRL2

  • C-C chemokine receptor-like 2
  • chemokine (C-C motif) receptor-like 2
  • c-C chemokine receptor-like 2-like
  • atypical chemokine receptor 5
  • chemokine receptor CCR11
  • chemokine receptor X
  • putative MCP-1 chemokine receptor
  • G-protein coupled beta chemokine receptor
  • chemokine (C-C) receptor 1,-like 2
  • chemokine (C-C) receptor 1-like 2
  • lipopolysaccharide inducible C-C chemokine receptor related
  • lipopolysaccharide-inducible C-C chemokine receptor
  • lipopolysacharide-inducible C-C chemokine receptor
  • chemokine C-C motif receptor-like 2
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