CCR3 Products
(Chemokine (C-C Motif) Receptor 3 (CCR3))
Categories
The protein encoded by this gene is a receptor for C-C type chemokines. It belongs to family 1 of the G protein-coupled receptors. This receptor binds and responds to a variety of chemokines, including eotaxin (CCL11), eotaxin-3 (CCL26), MCP-3 (CCL7), MCP-4 (CCL13), and RANTES (CCL5). It is highly expressed in eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1. This gene and seven other chemokine receptor genes form a chemokine receptor gene cluster on the chromosomal region 3p21. Alternatively spliced transcript variants have been described. [provided by RefSeq, Sep 2009].
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Featured CCR3 Categories
CCR3 Antibodies
High quality antibodies with extensive validation data.
CCR3 ELISA Kits
Reliable ELISA kits for a wide range of species.
CCR3 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended CCR3 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ELISA, FACS
Validations
- (5)
Cat. No.
ABIN5611257
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC (p), IF (cc), IF (p), IHC (fro)
Validations
- (4)
Cat. No.
ABIN738651
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC, IF
Validations
- (3)
Cat. No.
ABIN7145926
Quantity
100 μg
Datasheet
Datasheet
Recommended CCR3 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6965709
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6954648
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN5593527
Quantity
96 tests
Datasheet
Datasheet
Recommended CCR3 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (2)
Cat. No.
ABIN7491559
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN6964390
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1348497
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our CCR3 products
: "Crucial role of OX40/OX40L signaling in a murine model of asthma." in: Molecular medicine reports, Vol. 17, Issue 3, pp. 4213-4220, (2018) (PubMed).: "Regulation of eosinophilia and allergic airway inflammation by the glycan-binding protein galectin-1." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 113, Issue 33, pp. E4837-46, (2016) (PubMed).
: "CCL2/CCR2 Regulates the Tumor Microenvironment in HER-2/neu-Driven Mammary Carcinomas in Mice." in: PLoS ONE, Vol. 11, Issue 11, pp. e0165595, (2016) (PubMed).
: "Late IL-3-induced phenotypic and functional alterations in human basophils require continuous IL-3 receptor signaling." in: Journal of leukocyte biology, Vol. 101, Issue 1, pp. 227-238, (2016) (PubMed).
: "Evidence for chemokine synergy during neutrophil migration in ARDS." in: Thorax, Vol. 72, Issue 1, pp. 66-73, (2016) (PubMed).
: "Expression and prognostic significance of CCL11/CCR3 in glioblastoma." in: Oncotarget, Vol. 7, Issue 22, pp. 32617-27, (2016) (PubMed).
: "Hypoxia induced CCL28 promotes angiogenesis in lung adenocarcinoma by targeting CCR3 on endothelial cells." in: Scientific reports, Vol. 6, pp. 27152, (2016) (PubMed).
: "Simvastatin Inhibits IL-5-Induced Chemotaxis and CCR3 Expression of HL-60-Derived and Human Primary Eosinophils." in: PLoS ONE, Vol. 11, Issue 6, pp. e0157186, (2016) (PubMed).
: "Generation of eosinophils from cryopreserved murine bone marrow cells." in: PLoS ONE, Vol. 9, Issue 12, pp. e116141, (2015) (PubMed).
: "Eosinophils contribute to the resolution of lung-allergic responses following repeated allergen challenge." in: The Journal of allergy and clinical immunology, Vol. 135, Issue 2, pp. 451-60, (2015) (PubMed).
Synonyms and alternative names related to CCR3
C-C motif chemokine receptor 3 (CCR3), chemokine (C-C motif) receptor 3 (Ccr3), C-C motif chemokine receptor 3 (Ccr3), CC-CKR-3, CC-CKR3, CD193, CKR3, Cmkbr1l2, CMKBR3, Cmkbr3Protein level used designations for CCR3
- C-C CKR-3
- C-C chemokine receptor type 3
- CC chemokine receptor 3
- CCR-3
- b-chemokine receptor
- eosinophil CC chemokine receptor 3
- eosinophil eotaxin receptor
- CC-CKR-3
- MIP-1 alpha RL2
- MIP-1 alphaRL2
- chemokine (C-C) receptor 1,-like 2
- chemokine (C-C) receptor 3
- macrophage inflammatory protein 1-alpha receptor-like 2
- probable C-C chemokine receptor type 3
- CKR3
- C-C chemokine receptor 3
- eotaxin receptor CCR3
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