CCR2 Products
(Chemokine (C-C Motif) Receptor 2 (CCR2))
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This gene encodes a chemokine receptor like protein, which is predicted to be a seven transmembrane protein and most closely related to CCR1. Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. This gene is expressed at high levels in primary neutrophils and primary monocytes, and is further upregulated on neutrophil activation and during monocyte to macrophage differentiation. The function of this gene is unknown. This gene is mapped to the region where the chemokine receptor gene cluster is located. [provided by RefSeq, Jul 2008].
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Featured CCR2 Categories
CCR2 Antibodies
High quality antibodies with extensive validation data.
CCR2 ELISA Kits
Reliable ELISA kits for a wide range of species.
CCR2 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended CCR2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, FACS, IHC, ICC, Neut
Validations
- (4)
Cat. No.
ABIN7193322
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (2)
Cat. No.
ABIN7188602
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Dog, Human, Mouse, Rat
Application
IHC (p), IF (p)
Validations
- (1)
- (1)
Cat. No.
ABIN670146
Quantity
100 μL
Datasheet
Datasheet
Recommended CCR2 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6965708
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6962428
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6954646
Quantity
96 tests
Datasheet
Datasheet
Recommended CCR2 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7491557
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (2)
Cat. No.
ABIN7448153
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (2)
Cat. No.
ABIN7448154
Quantity
100 μL
Datasheet
Datasheet
Latest Publications for our CCR2 products
: "Endothelial cell-specific redox gene modulation inhibits angiogenesis but promotes B16F0 tumor growth in mice." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 33, Issue 12, pp. 14147-14158, (2020) (PubMed).: "Bacterial and viral pathogen-associated molecular patterns induce divergent early transcriptomic landscapes in a bovine macrophage cell line." in: BMC genomics, Vol. 20, Issue 1, pp. 15, (2019) (PubMed).
: "Histone H3 Serine 10 Phosphorylation Facilitates Endothelial Activation in Diabetic Kidney Disease." in: Diabetes, Vol. 67, Issue 12, pp. 2668-2681, (2019) (PubMed).
: "Salt increases monocyte CCR2 expression and inflammatory responses in humans." in: JCI insight, Vol. 4, Issue 21, (2019) (PubMed).
: "Kartogenin inhibits pain behavior, chondrocyte inflammation, and attenuates osteoarthritis progression in mice through induction of IL-10." in: Scientific reports, Vol. 8, Issue 1, pp. 13832, (2019) (PubMed).
: "C/EBPδ drives interactions between human MAIT cells and endothelial cells that are important for extravasation." in: eLife, Vol. 7, (2018) (PubMed).
: "Modulating Macrophage Polarization through CCR2 Inhibition and Multivalent Engagement." in: Molecular pharmaceutics, Vol. 15, Issue 7, pp. 2721-2731, (2018) (PubMed).
: "The Spleen Promotes the Secretion of CCL2 and Supports an M1 Dominant Phenotype in Hepatic Macrophages During Liver Fibrosis." in: Cellular physiology and biochemistry : international journal of experimental cellular physiology, biochemistry, and pharmacology, Vol. 51, Issue 2, pp. 557-574, (2018) (PubMed).
: "Direct role of the C-C motif chemokine receptor 2/monocyte chemoattractant protein 1 system in the feline cumulus oocyte complex." in: Biology of reproduction, (2018) (PubMed).
: "Kif4A mediate the accumulation and reeducation of THP-1 derived macrophages via regulation of CCL2-CCR2 expression in crosstalking with OSCC." in: Scientific reports, Vol. 7, Issue 1, pp. 2226, (2018) (PubMed).
Synonyms and alternative names related to CCR2
C-C motif chemokine receptor 2 (CCR2), C-C motif chemokine receptor like 2 (CCRL2), chemokine (C-C motif) receptor 2 (Ccr2), C-C motif chemokine receptor 2 (Ccr2), C-C motif chemokine receptor 2 (LOC484790), chemokine (C-C motif) receptor 2 (CCR2), ACKR5, CC-CKR-2, Cc-ckr-2, CCR-2, CCR2A, Ccr2a, CCR2B, Ccr2b, CD192, CKR2, Ckr2, CKR2A, Ckr2a, CKR2B, Ckr2b, CKRX, CMKBR2, Cmkbr2, CRAM, CRAM-A, CRAM-B, HCR, MCP-1-R, mJe-rProtein level used designations for CCR2
- C-C chemokine receptor type 2
- MCP-1 receptor
- monocyte chemoattractant protein 1 receptor
- monocyte chemotactic protein 1 receptor
- C-C chemokine receptor-like 2
- atypical chemokine receptor 5
- chemokine receptor CCR11
- chemokine receptor X
- putative MCP-1 chemokine receptor
- C-C CHEMOKINE RECEPTOR TYPE 2 (C-C CKR-2) (CC-CKR-2) (CCR-2) (CCR2) (JE/FIC RECEPTOR) (MCP-1 RECEPTOR)
- C-C CKR-2
- CCR-2
- JE/FIC receptor
- MIP-1 alphaR
- chemoattractant protein-1 receptor
- chemokine (C-C) receptor 2
- CC-CKR-2
- chemokine receptor CCR2
- MCP-1-R
- chemokine receptor
- chemokine C-C motif receptor 2
- chemokine (C-C motif) receptor 2
- chemokine CC-motif receptor type 2
- chemokine receptor type 2
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