CCR1 Products
(Chemokine (C-C Motif) Receptor 1 (CCR1))
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This gene encodes a member of the beta chemokine receptor family, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. The ligands of this receptor include macrophage inflammatory protein 1 alpha (MIP-1 alpha), regulated on activation normal T expressed and secreted protein (RANTES), monocyte chemoattractant protein 3 (MCP-3), and myeloid progenitor inhibitory factor-1 (MPIF-1). Chemokines and their receptors mediated signal transduction are critical for the recruitment of effector immune cells to the site of inflammation. Knockout studies of the mouse homolog suggested the roles of this gene in host protection from inflammatory response, and susceptibility to virus and parasite. This gene and other chemokine receptor genes, including CCR2, CCRL2, CCR3, CCR5 and CCXCR1, are found to form a gene cluster on chromosome 3p. [provided by RefSeq, Jul 2008].
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Featured CCR1 Categories
CCR1 Antibodies
High quality antibodies with extensive validation data.
CCR1 ELISA Kits
Reliable ELISA kits for a wide range of species.
CCR1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended CCR1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
ELISA, FACS
Validations
- (4)
Cat. No.
ABIN5611255
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, WB, FACS, IHC
Validations
- (5)
Cat. No.
ABIN3030216
Quantity
0.4 mL
Datasheet
Datasheet
Reactivity
Human
Application
ELISA, WB, IHC, IF
Validations
- (3)
Cat. No.
ABIN7145918
Quantity
100 μg
Datasheet
Datasheet
Recommended CCR1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Cow
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6965707
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6954643
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6954644
Quantity
96 tests
Datasheet
Datasheet
Recommended CCR1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (2)
Cat. No.
ABIN7491555
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (1)
Cat. No.
ABIN6964237
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN2565240
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our CCR1 products
: "A novel multi-target RNAi adenovirus inhibits hepatoma cell proliferation, migration, and induction of angiogenesis." in: Oncotarget, Vol. 7, Issue 36, pp. 57705-57713, (2018) (PubMed).: "Role of interleukin-4, the chemokine CCL3 and its receptor CCR5 in neuropathic pain." in: Molecular immunology, Vol. 77, pp. 184-92, (2016) (PubMed).
: "Evidence for chemokine synergy during neutrophil migration in ARDS." in: Thorax, Vol. 72, Issue 1, pp. 66-73, (2016) (PubMed).
: "The generation of macrophages with anti-inflammatory activity in the absence of STAT6 signaling." in: Journal of leukocyte biology, Vol. 98, Issue 3, pp. 395-407, (2015) (PubMed).
: "IL-15 amplifies the pathogenic properties of CD4+CD28- T cells in multiple sclerosis." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 194, Issue 5, pp. 2099-109, (2015) (PubMed).
: "TLR5 Ligand-Secreting T Cells Reshape the Tumor Microenvironment and Enhance Antitumor Activity." in: Cancer research, Vol. 75, Issue 10, pp. 1959-71, (2015) (PubMed).
: "NF-κB-direct activation of microRNAs with repressive effects on monocyte-specific genes is critical for osteoclast differentiation." in: Genome biology, Vol. 16, pp. 2, (2015) (PubMed).
: "CCR1 plays a critical role in modulating pain through hematopoietic and non-hematopoietic cells. ..." in: PLoS ONE, Vol. 9, Issue 8, pp. e105883, (2015) (PubMed).
: "Mechanisms by which chronic ethanol feeding impairs the migratory capacity of cutaneous dendritic cells." in: Alcoholism, clinical and experimental research, Vol. 37, Issue 12, pp. 2098-107, (2013) (PubMed).
: "Distinct functions of chemokine receptor axes in the atherogenic mobilization and recruitment of classical monocytes." in: EMBO molecular medicine, Vol. 5, Issue 3, pp. 471-81, (2013) (PubMed).
Synonyms and alternative names related to CCR1
C-C motif chemokine receptor 1 (CCR1), chemokine (C-C motif) receptor 1 (Ccr1), C-C motif chemokine receptor 1 (Ccr1), CD191, CKR-1, CKR1, CMKBR1, Cmkbr1, HM145, Mip-1a-R, MIP1aR, SCYAR1Protein level used designations for CCR1
- C-C CKR-1
- C-C chemokine receptor type 1
- CC-CKR-1
- CCR-1
- LD78 receptor
- MIP-1alpha-R
- RANTES receptor
- RANTES-R
- macrophage inflammatory protein 1-alpha receptor
- MIP-1 alpha R
- MIP-1 alphaR
- chemokine (C-C) receptor 1
- macrophage inflammatory protein-1 alpha receptor
- chemokine receptor
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