CCNDBP1 Products
(Cyclin D-Type Binding-Protein 1 (CCNDBP1))
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This gene was identified by the interaction of its gene product with Grap2, a leukocyte-specific adaptor protein important for immune cell signaling. The protein encoded by this gene was shown to interact with cyclin D. Transfection of this gene in cells was reported to reduce the phosphorylation of Rb gene product by cyclin D-dependent protein kinase, and inhibit E2F1-mediated transcription activity. This protein was also found to interact with helix-loop-helix protein E12 and is thought to be a negative regulator of liver-specific gene expression. Several alternatively spliced variants have been found for this gene. [provided by RefSeq, Apr 2009].
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Featured CCNDBP1 Categories
CCNDBP1 Antibodies
High quality antibodies with extensive validation data.
CCNDBP1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended CCNDBP1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (3)
Cat. No.
ABIN525281
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (5)
- (1)
Cat. No.
ABIN1881181
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p)
Validations
- (2)
Cat. No.
ABIN2856378
Quantity
100 μL
Datasheet
Datasheet
Recommended CCNDBP1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1348455
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1348457
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN2713325
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our CCNDBP1 products
: "A novel senescence-evasion mechanism involving Grap2 and Cyclin D interacting protein inactivation by Ras associated with diabetes in cancer cells under doxorubicin treatment." in: Cancer research, Vol. 70, Issue 11, pp. 4357-65, (2010) (PubMed).: "Crystallization and preliminary X-ray diffraction analysis of GCIP/HHM transcriptional regulator." in: Acta crystallographica. Section F, Structural biology and crystallization communications, Vol. 65, Issue Pt 1, pp. 21-4, (2009) (PubMed).
: "An Id-like molecule, HHM, is a synexpression group-restricted regulator of TGF-beta signalling." in: The EMBO journal, Vol. 27, Issue 22, pp. 2955-65, (2008) (PubMed).
: "Immunohistochemical expression of GCIP in breast carcinoma: relationship with tumour grade, disease-free survival, mucinous differentiation and response to chemotherapy." in: Histopathology, Vol. 53, Issue 5, pp. 554-60, (2008) (PubMed).
: "Ribosomal phosphoprotein P0 interacts with GCIP and overexpression of P0 is associated with cellular proliferation in breast and liver carcinoma cells." in: Oncogene, Vol. 27, Issue 3, pp. 332-8, (2008) (PubMed).
: "p29, a novel GCIP-interacting protein, localizes in the nucleus." in: Biochemical and biophysical research communications, Vol. 279, Issue 2, pp. 732-7, (2001) (PubMed).
: "GCIP, a novel human grap2 and cyclin D interacting protein, regulates E2F-mediated transcriptional activity." in: The Journal of biological chemistry, Vol. 275, Issue 27, pp. 20942-8, (2000) (PubMed).
Synonyms and alternative names related to CCNDBP1
cyclin D1 binding protein 1 (CCNDBP1), cyclin D-type binding-protein 1 (ccndbp1), cyclin D-type binding-protein 1 (Ccndbp1), cyclin D1 binding protein 1 (Ccndbp1), AU022347, CCNDBP1, dip1, DIP1, gcip, GCIP, HHM, Maid, SECC-8, SSEC-8Protein level used designations for CCNDBP1
- cyclin D-type binding-protein 1
- D-type cyclin-interacting protein 1
- cyclin-D1-binding protein 1
- grap2 and cyclin-D-interacting protein
- human homolog of Maid
- maternal Id-like protein
- maternal inhibition of differentiation
- stage specific embryonic cDNA-8 protein
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