CCL2 Products
(Chemokine (C-C Motif) Ligand 2 (CCL2))
Categories
This gene is one of several cytokine genes clustered on the q-arm of chromosome 17. Cytokines are a family of secreted proteins involved in immunoregulatory and inflammatory processes. The protein encoded by this gene is structurally related to the CXC subfamily of cytokines. Members of this subfamily are characterized by two cysteines separated by a single amino acid. This cytokine displays chemotactic activity for monocytes and basophils but not for neutrophils or eosinophils. It has been implicated in the pathogenesis of diseases characterized by monocytic infiltrates, like psoriasis, rheumatoid arthritis and atherosclerosis. It binds to chemokine receptors CCR2 and CCR4. [provided by RefSeq, Jul 2008].
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Featured CCL2 Categories
CCL2 Antibodies
High quality antibodies with extensive validation data.
CCL2 ELISA Kits
Reliable ELISA kits for a wide range of species.
CCL2 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended CCL2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, ELISA, ICC, FACS
Validations
- (2)
- (7)
Cat. No.
ABIN969505
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC (p), IF (p), IHC (fro), IF (cc)
Validations
- (10)
- (4)
Cat. No.
ABIN737676
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC (p), IF, FACS
Validations
- (1)
- (5)
Cat. No.
ABIN390653
Quantity
400 μL
Datasheet
Datasheet
Recommended CCL2 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (5)
- (1)
- (1)
Cat. No.
ABIN365052
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse, Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (16)
- (1)
Cat. No.
ABIN6954595
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (33)
- (1)
Cat. No.
ABIN411320
Quantity
96 tests
Datasheet
Datasheet
Recommended CCL2 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7275241
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (2)
Cat. No.
ABIN7275240
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Cynomolgus
Source
HEK-293 Cells
Validations
- (2)
Cat. No.
ABIN7275239
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our CCL2 products
: "Pharmacological activation of SIRT1 by metformin prevented trauma-induced heterotopic ossification through inhibiting macrophage mediated inflammation." in: European journal of pharmacology, Vol. 909, pp. 174386, (2022) (PubMed).: "Screening of anti-chronic nonbacterial prostatitis activity of different extractions of the aerial part of Glycyrrhiza uralensis, and network pharmacology research." in: Biomedical reports, Vol. 15, Issue 6, pp. 99, (2021) (PubMed).
: "Quercetin Attenuates Trauma-Induced Heterotopic Ossification by Tuning Immune Cell Infiltration and Related Inflammatory Insult." in: Frontiers in immunology, Vol. 12, pp. 649285, (2021) (PubMed).
: "DHEAS prevents pro-metastatic and proliferative effects of 17ß-estradiol on MCF-7 breast cancer cells." in: Biochimica et biophysica acta. Molecular cell research, Vol. 1867, Issue 2, pp. 118600, (2020) (PubMed).
: "LncRNA HOXA11-AS regulates calcium oxalate crystal-induced renal inflammation via miR-124-3p/MCP-1." in: Journal of cellular and molecular medicine, Vol. 24, Issue 1, pp. 238-249, (2020) (PubMed).
: "β-Defensin Strengthens Antimicrobial Peritoneal Mast Cell Response." in: Journal of immunology research, Vol. 2020, pp. 5230172, (2020) (PubMed).
: "Protective function of exosomes from adipose tissue-derived mesenchymal stem cells in acute kidney injury through SIRT1 pathway." in: Life sciences, Vol. 255, pp. 117719, (2020) (PubMed).
: "Inhibition of LOX-1 prevents inflammation and photoreceptor cell death in retinal degeneration." in: International immunopharmacology, Vol. 80, pp. 106190, (2020) (PubMed).
: "Alpha-Mangostin Improves Cardiac Hypertrophy and Fibrosis and Associated Biochemical Parameters in High-Fat/High-Glucose Diet and Low-Dose Streptozotocin Injection-Induced Type 2 Diabetic Rats." in: Journal of experimental pharmacology, Vol. 12, pp. 27-38, (2020) (PubMed).
: "Intracellular virus sensor MDA5 exacerbates vitiligo by inducing the secretion of chemokines in keratinocytes under virus invasion." in: Cell death & disease, Vol. 11, Issue 6, pp. 453, (2020) (PubMed).
Synonyms and alternative names related to CCL2
C-C motif chemokine ligand 2 (CCL2), chemokine (C-C motif) ligand 2 (Ccl2), C-C motif chemokine ligand 2 (Ccl2), chemokine (C-C motif) ligand 2 (CCL2), C-C motif chemokine 2 (LOC101120093), AI323594, GDCF-2, HC11, HSMCR30, JE, MCAF, MCP-1, MCP-1A, MCP1, MCP1A, SCYA2, Scya2, Sigje, SMC-CFProtein level used designations for CCL2
- C-C motif chemokine 2
- monocyte chemoattractant protein 1
- monocyte chemoattractant protein-1
- monocyte chemotactic and activating factor
- monocyte chemotactic protein 1
- monocyte secretory protein JE
- small inducible cytokine A2 (monocyte chemotactic protein 1, homologous to mouse Sig-je)
- small inducible cytokine subfamily A (Cys-Cys), member 2
- small-inducible cytokine A2
- platelet-derived growth factor-inducible protein JE
- small inducible cytokine A2
- immediate-early serum-responsive JE protein
- immediate-early serum-responsive protein JE
- small inducible gene JE
- MCP-1
- acidic seminal fluid protein
- monocyte chemotactic protein 1A
- chemokine CCL2/MCP-1
- Monocyte chemoattractant protein 1
- Monocyte chemotactic protein 1
- Small-inducible cytokine A2
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