CCDC98 Products
(Family with Sequence Similarity 175, Member A (FAM175A))
Categories
Component of the BRCA1-A complex, a complex that specifically recognizes 'Lys-63'-linked ubiquitinated histones H2A and H2AX at DNA lesions sites, leading to target the brca1-bard1 heterodimer to sites of DNA damage at double-strand breaks (DSBs). The BRCA1-A complex also possesses deubiquitinase activity that specifically removes 'Lys-63'-linked ubiquitin on histones H2A and H2AX. In the BRCA1-A complex, it acts as a central scaffold protein that assembles the various components of the BRCA1-A complex and mediates the recruitment of brca1 (By similarity).
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Featured CCDC98 Categories
CCDC98 Antibodies
High quality antibodies with extensive validation data.
CCDC98 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended CCDC98 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Application
WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
- (2)
Cat. No.
ABIN872878
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IP, FACS
Validations
- (2)
Cat. No.
ABIN1302443
Quantity
0.1 mg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IP, IHC, IHC (p), FACS
Validations
- (2)
Cat. No.
ABIN574440
Quantity
0.05 mg
Datasheet
Datasheet
Recommended CCDC98 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6227801
Quantity
96 tests
Datasheet
Datasheet
Recommended CCDC98 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Monkey
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN2749553
Quantity
5 applications
Datasheet
Datasheet
Reactivity
Zebrafish (Danio rerio)
Source
Yeast
Validations
Cat. No.
ABIN1621126
Quantity
1 mg
Datasheet
Datasheet
Reactivity
Atlantic Salmon
Source
Yeast
Validations
Cat. No.
ABIN1655535
Quantity
1 mg
Datasheet
Datasheet
Latest Publications for our CCDC98 products
: "CCDC98 is a BRCA1-BRCT domain-binding protein involved in the DNA damage response." in: Nature structural & molecular biology, Vol. 14, Issue 8, pp. 710-5, (2007) (PubMed).: "CCDC98 targets BRCA1 to DNA damage sites." in: Nature structural & molecular biology, Vol. 14, Issue 8, pp. 716-20, (2007) (PubMed).
: "Abraxas and RAP80 form a BRCA1 protein complex required for the DNA damage response." in: Science (New York, N.Y.), Vol. 316, Issue 5828, pp. 1194-8, (2007) (PubMed).
Synonyms and alternative names related to CCDC98
abraxas 1, BRCA1 A complex subunit (ABRAXAS1), Coiled-coil domain-containing protein 98 (abraxas1), BRCA1 A complex subunit (Abraxas1), abraxas 1, BRCA1 A complex subunit (Abraxas1), family with sequence similarity 175 member A (FAM175A), abraxas 2a, BRISC complex subunit (abraxas2a), abraxas 1, BRCA1 A complex subunit S homeolog (abraxas1.S), 3830405G04Rik, 5630400M01Rik, abra1, ABRA1, AI506069, AL024423, AV118690, CCDC98, ccdc98, Ccdc98, fam175a, RGD1305287, zgc:103522Protein level used designations for CCDC98
- coiled-coil domain containing 98
- BRCA1-A complex subunit Abraxas
- Protein FAM175A
- abraxas protein
- coiled-coil domain-containing protein 98
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