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CCDC8 Products

(Coiled-Coil Domain Containing 8 (CCDC8))

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This gene encodes a coiled-coil domain-containing protein. The encoded protein functions as a cofactor required for p53-mediated apoptosis following DNA damage, and may also play a role in growth through interactions with the cytoskeletal adaptor protein obscurin-like 1. Mutations in this gene are a cause of 3M syndrome-3 (3M3). [provided by RefSeq, Dec 2011].

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Featured CCDC8 Categories

CCDC8 Antibodies

High quality antibodies with extensive validation data.

CCDC8 ELISA Kits

Reliable ELISA kits for a wide range of species.

CCDC8 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended CCDC8 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB
Validations
  • (1)
  • (3)
Cat. No. ABIN949718
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IF
Validations
  • (2)
Cat. No. ABIN7148148
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IHC
Validations
  • (2)
Cat. No. ABIN6260529
Quantity 100 μL
Datasheet Datasheet

Recommended CCDC8 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Sheep
Analytical Method
Validations
Cat. No. ABIN1773898
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Competition ELISA
Validations
Cat. No. ABIN1745434
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Competition ELISA
Validations
Cat. No. ABIN1742994
Quantity 96 tests
Datasheet Datasheet

Recommended CCDC8 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Source Yeast
Validations
Cat. No. ABIN1476173
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our CCDC8 products

Hanson, Stevens, Murray, Black, Clayton: "Identifying biological pathways that underlie primordial short stature using network analysis." in: Journal of molecular endocrinology, Vol. 52, Issue 3, pp. 333-44, (2014) (PubMed).

Stadler, Rexhepaj, Singan, Murphy, Pepperkok, Uhlén, Simpson, Lundberg: "Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells." in: Nature methods, Vol. 10, Issue 4, pp. 315-23, (2013) (PubMed).

Hanson, Murray, OSullivan, Urquhart, Daly, Bhaskar, Biesecker, Skae, Smith, Cole, Kirk, Chandler, Kingston, Donnai, Clayton, Black: "Exome sequencing identifies CCDC8 mutations in 3-M syndrome, suggesting that CCDC8 contributes in a pathway with CUL7 and OBSL1 to control human growth." in: American journal of human genetics, Vol. 89, Issue 1, pp. 148-53, (2011) (PubMed).

Dai, Tang, Jung, Qin, Aaronson, Gu: "Differential effects on p53-mediated cell cycle arrest vs. apoptosis by p90." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 108, Issue 47, pp. 18937-42, (2011) (PubMed).

Synonyms and alternative names related to CCDC8

coiled-coil domain containing 8 (CCDC8), coiled-coil domain containing 8 (Ccdc8), 3M3, ENSMUSG00000041117, p90, PPP1R20

Protein level used designations for CCDC8

  • coiled-coil domain-containing protein 8
  • protein phosphatase 1, regulatory subunit 20
  • probable Coiled-coil domain-containing protein 8
  • coiled-coil domain-containing protein 8 homolog
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