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CCDC50 Products

(Coiled-Coil Domain Containing 50 (CCDC50))
This gene encodes a soluble, cytoplasmic, tyrosine-phosphorylated protein with multiple ubiquitin-interacting domains. Mutations in this gene cause nonsyndromic, postlingual, progressive sensorineural DFNA44 hearing loss. In mouse, the protein is expressed in the inner ear during development and postnatal maturation and associates with microtubule-based structures. This protein may also function as a negative regulator of NF-kB signaling and as an effector of epidermal growth factor (EGF)-mediated cell signaling. Alternative splicing results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Oct 2008].

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Featured CCDC50 Categories

CCDC50 Antibodies

High quality antibodies with extensive validation data.

CCDC50 ELISA Kits

Reliable ELISA kits for a wide range of species.

CCDC50 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended CCDC50 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IHC (p), ICC, IF
Validations
  • (3)
Cat. No. ABIN1497124
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application ELISA, IHC
Validations
  • (1)
Cat. No. ABIN185310
Quantity 100 μg
Datasheet Datasheet
Reactivity Human, Monkey
Application WB
Validations
  • (1)
Cat. No. ABIN960112
Quantity 100 μg
Datasheet Datasheet

Recommended CCDC50 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Sheep
Analytical Method
Validations
Cat. No. ABIN1773872
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Competition ELISA
Validations
Cat. No. ABIN1745408
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Competition ELISA
Validations
Cat. No. ABIN1742968
Quantity 96 tests
Datasheet Datasheet

Recommended CCDC50 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (1)
Cat. No. ABIN2735728
Quantity 20 μg
Datasheet Datasheet
Reactivity Rat
Source Yeast
Validations
Cat. No. ABIN1678389
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our CCDC50 products

Farfsing, Engel, Seiffert, Hartmann, Ott, Rosenwald, Stilgenbauer, Döhner, Boutros, Lichter, Pscherer: "Gene knockdown studies revealed CCDC50 as a candidate gene in mantle cell lymphoma and chronic lymphocytic leukemia." in: Leukemia, Vol. 23, Issue 11, pp. 2018-26, (2009) (PubMed).

Blagoev, Ong, Kratchmarova, Mann: "Temporal analysis of phosphotyrosine-dependent signaling networks by quantitative proteomics." in: Nature biotechnology, Vol. 22, Issue 9, pp. 1139-45, (2004) (PubMed).

Synonyms and alternative names related to CCDC50

coiled-coil domain containing 50 (CCDC50), coiled-coil domain containing 50 L homeolog (ccdc50.L), coiled-coil domain containing 50 (ccdc50), coiled-coil domain containing 50 (Ccdc50), 2610529H08Rik, 5730448P06Rik, AW048328, AW546090, C3orf6, c3orf6, C3orf6h, D16Bwg1543e, DFNA44, ymer, YMER

Protein level used designations for CCDC50

  • coiled-coil domain containing 50
  • Ymer protein
  • coiled-coil domain-containing protein 50
  • protein Ymer
  • putative C3orf6 protein homolog
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