CCBP2 Products
(Chemokine Binding Protein 2 (CCBP2))
Categories
This gene encodes a beta chemokine receptor, which is predicted to be a seven transmembrane protein similar to G protein-coupled receptors. Chemokines and their receptor-mediated signal transduction are critical for the recruitment of effector immune cells to the inflammation site. This gene is expressed in a range of tissues and hemopoietic cells. The expression of this receptor in lymphatic endothelial cells and overexpression in vascular tumors suggested its function in chemokine-driven recirculation of leukocytes and possible chemokine effects on the development and growth of vascular tumors. This receptor appears to bind the majority of beta-chemokine family members\; however, its specific function remains unknown. This gene is mapped to chromosome 3p21.3, a region that includes a cluster of chemokine receptor genes. [provided by RefSeq, Jul 2008].
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Featured CCBP2 Categories
CCBP2 Antibodies
High quality antibodies with extensive validation data.
CCBP2 ELISA Kits
Reliable ELISA kits for a wide range of species.
CCBP2 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended CCBP2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse
Application
WB, IHC (p)
Validations
- (3)
Cat. No.
ABIN388746
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, IHC (p)
Validations
- (2)
Cat. No.
ABIN388745
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, FACS
Validations
- (2)
Cat. No.
ABIN514487
Quantity
50 μL
Datasheet
Datasheet
Recommended CCBP2 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Analytical Method
Validations
Cat. No.
ABIN1126338
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Validations
Cat. No.
ABIN1126339
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Validations
Cat. No.
ABIN1126337
Quantity
96 tests
Datasheet
Datasheet
Recommended CCBP2 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7122348
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1776943
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
Cat. No.
ABIN1326605
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our CCBP2 products
: "The N-terminal region of the atypical chemokine receptor ACKR2 is a key determinant of ligand binding." in: The Journal of biological chemistry, Vol. 289, Issue 18, pp. 12330-42, (2014) (PubMed).: "Recognition versus adaptive up-regulation and degradation of CC chemokines by the chemokine decoy receptor D6 are determined by their N-terminal sequence." in: The Journal of biological chemistry, Vol. 284, Issue 38, pp. 26207-15, (2009) (PubMed).
: "Regulation of D6 chemokine scavenging activity by ligand- and Rab11-dependent surface up-regulation." in: Blood, Vol. 112, Issue 3, pp. 493-503, (2008) (PubMed).
: "Protection against inflammation- and autoantibody-caused fetal loss by the chemokine decoy receptor D6." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 104, Issue 7, pp. 2319-24, (2007) (PubMed).
: "CCR4 versus CCR10 in human cutaneous TH lymphocyte trafficking." in: Blood, Vol. 101, Issue 5, pp. 1677-82, (2003) (PubMed).
: "Cutting edge: scavenging of inflammatory CC chemokines by the promiscuous putatively silent chemokine receptor D6." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 170, Issue 5, pp. 2279-82, (2003) (PubMed).
: "CCR10 expression is a common feature of circulating and mucosal epithelial tissue IgA Ab-secreting cells." in: The Journal of clinical investigation, Vol. 111, Issue 7, pp. 1001-10, (2003) (PubMed).
Synonyms and alternative names related to CCBP2
atypical chemokine receptor 2 (ACKR2), atypical chemokine receptor 2 (Ackr2), atypical chemokine receptor 2-like (LOC100219492), chemokine receptor D6 (LOC733624), chemokine (C-C motif) receptor 9 (Ccr9), C-C motif chemokine receptor 9 (CCR9), C-C motif chemokine receptor 9 (Ccr9), A130091K22Rik, AI464239, CCBP2, Ccbp2, CCR9, CCR10, CMKBR9, Cmkbr9, Cmkbr10, D6, GPR-9-6, hD6, LOC733624Protein level used designations for CCBP2
- C-C chemokine receptor D6
- CC-chemokine-binding receptor JAB61
- chemokine (C-C motif) receptor 9
- chemokine (C-C) receptor 9
- chemokine binding protein 2
- chemokine receptor CCR-10
- chemokine receptor CCR-9
- chemokine receptor D6
- chemokine-binding protein 2
- chemokine-binding protein D6
- CCR10-related receptor
- C-C CKR-9
- C-C chemokine receptor type 9
- CC-CKR-9
- CCR-9
- chemokine C-C receptor 10
- D6 beta-chemokine receptor
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