CBS Products
(Cystathionine-beta-Synthase (CBS))
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The protein encoded by this gene acts as a homotetramer to catalyze the conversion of homocysteine to cystathionine, the first step in the transsulfuration pathway. The encoded protein is allosterically activated by adenosyl-methionine and uses pyridoxal phosphate as a cofactor. Defects in this gene can cause cystathionine beta-synthase deficiency (CBSD), which can lead to homocystinuria. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, May 2010].
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Featured CBS Categories
CBS Antibodies
High quality antibodies with extensive validation data.
CBS ELISA Kits
Reliable ELISA kits for a wide range of species.
CBS Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended CBS Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC (p), IP, RNAi
Validations
- (38)
- (8)
Cat. No.
ABIN7489109
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF
Validations
- (2)
- (6)
Cat. No.
ABIN3021959
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, IF, IHC (p), FACS
Validations
- (2)
- (5)
Cat. No.
ABIN1881141
Quantity
400 μL
Datasheet
Datasheet
Recommended CBS ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6974522
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6966188
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6966187
Quantity
96 tests
Datasheet
Datasheet
Recommended CBS Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (4)
- (1)
Cat. No.
ABIN1348191
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1348195
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1348197
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our CBS products
: "Dysregulated Sulfide Metabolism in Multiple Sclerosis: Serum and Vascular Endothelial Inflammatory Responses." in: Pathophysiology : the official journal of the International Society for Pathophysiology, Vol. 29, Issue 3, pp. 570-582, (2022) (PubMed).: "2,3,7,8-Tetrachlorodibenzo-p-dioxin (TCDD) dysregulates hepatic one carbon metabolism during the progression of steatosis to steatohepatitis with fibrosis in mice." in: Scientific reports, Vol. 10, Issue 1, pp. 14831, (2021) (PubMed).
: "Transcriptomic Analysis of the Mechanisms for Alleviating Psoriatic Dermatitis Using Taodan Granules in an Imiquimod-Induced Psoriasis-like Mouse Model." in: Frontiers in pharmacology, Vol. 12, pp. 632414, (2021) (PubMed).
: "Allosteric control of human cystathionine β-synthase activity by a redox active disulfide bond." in: The Journal of biological chemistry, Vol. 293, Issue 7, pp. 2523-2533, (2018) (PubMed).
: "Relationship between selenoprotein P and selenocysteine lyase: Insights into selenium metabolism." in: Free radical biology & medicine, Vol. 127, pp. 182-189, (2018) (PubMed).
: "Hydrogen Sulfide Is a Novel Regulator of Bone Formation Implicated in the Bone Loss Induced by Estrogen Deficiency." in: Journal of bone and mineral research : the official journal of the American Society for Bone and Mineral Research, Vol. 31, Issue 5, pp. 949-63, (2016) (PubMed).
: "Downregulation of Glutathione Biosynthesis Contributes to Oxidative Stress and Liver Dysfunction in Acute Kidney Injury." in: Oxidative medicine and cellular longevity, Vol. 2016, pp. 9707292, (2016) (PubMed).
: "Heme Oxygenase-1 Promotes Delayed Wound Healing in Diabetic Rats." in: Journal of diabetes research, Vol. 2016, pp. 9726503, (2016) (PubMed).
: "Folic acid deficiency induces premature hearing loss through mechanisms involving cochlear oxidative stress and impairment of homocysteine metabolism." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 29, Issue 2, pp. 418-32, (2015) (PubMed).
: "Tadalafil Integrates Nitric Oxide-Hydrogen Sulfide Signaling to Inhibit High Glucose-induced Matrix Protein Synthesis in Podocytes." in: The Journal of biological chemistry, Vol. 290, Issue 19, pp. 12014-26, (2015) (PubMed).
Synonyms and alternative names related to CBS
cystathionine-beta-synthase L homeolog (cbs.L), cystathionine-beta-synthase (cbs), cystathionine beta-synthase (Cbs), cystathionine-beta-synthase (CBS), cystathionine beta-synthase (CNA06170), cystathionine beta-synthase (Tb11.02.5400), cystathionine beta-synthase CBS (cbs), cystathionine beta-synthase (cbs), cystathionine beta-synthase (cysB), cystathionine beta-synthase (LOC100635325), cystathionine beta synthase (Cbs), cystathionine-beta-synthase S homeolog (cbs.S), cystathionine-beta-synthase b (cbsb), AI047524, AI303044, cb442, CBS, cbs, DDBDRAFT_0189727, DDBDRAFT_0191292, DDB_0189727, DDB_0191292, GB12529, hip4, HIP4, wu:fb37g05, wu:fm61c07, wu:fq06c06, zgc:113704Protein level used designations for CBS
- cystathionine-beta-synthase
- cystathionine beta-synthase
- cystathionine beta-synthase CBS
- beta-thionase
- hemoprotein H-450
- serine sulfhydrase
- methylcysteine synthase
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