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CBR1 Products

(Carbonyl Reductase 1 (CBR1))

Categories

Carbonyl reductase is one of several monomeric, NADPH-dependent oxidoreductases having wide specificity for carbonyl compounds. This enzyme is widely distributed in human tissues. Another carbonyl reductase gene, CRB3, lies close to this gene on chromosome 21q. [provided by RefSeq, Jul 2008].

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Featured CBR1 Categories

CBR1 Antibodies

High quality antibodies with extensive validation data.

CBR1 ELISA Kits

Reliable ELISA kits for a wide range of species.

CBR1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended CBR1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (8)
Cat. No. ABIN184784
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Application WB, IHC, ICC, IP
Validations
  • (4)
Cat. No. ABIN7444337
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC
Validations
  • (3)
Cat. No. ABIN7236216
Quantity 200 μL
Datasheet Datasheet

Recommended CBR1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6975474
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method
Validations
Cat. No. ABIN1125311
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method
Validations
Cat. No. ABIN1125314
Quantity 96 tests
Datasheet Datasheet

Recommended CBR1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
Cat. No. ABIN1348184
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN935034
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7418506
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our CBR1 products

Yun, Choi, Lee, Kong, Sung, Kim, Eun: "Carbonyl reductase 1 is a new target to improve the effect of radiotherapy on head and neck squamous cell carcinoma." in: Journal of experimental & clinical cancer research : CR, Vol. 37, Issue 1, pp. 264, (2019) (PubMed).

Gutiérrez-Salinas, García-Ortiz, Mondragón-Terán, Hernández-Rodríguez, Ramírez-García, Núñez-Ramos: "[Assessment of the concentrations of carbonylated proteins and carbonyl reductase enzyme in mexican women with breast cancer: A pilot study]." in: Gaceta médica de México, Vol. 152, Issue 1, pp. 13-8, (2016) (PubMed).

Atsriku, Hoffmann, Moghaddam, Kumar, Surapaneni: "In vitro metabolism of a novel JNK inhibitor tanzisertib: interspecies differences in oxido-reduction and characterization of enzymes involved in metabolism." in: Xenobiotica; the fate of foreign compounds in biological systems, Vol. 45, Issue 6, pp. 465-80, (2015) (PubMed).

Mitani, Ito, Harada, Nakano, Inui, Ashida, Yamaji: "Resveratrol reduces the hypoxia-induced resistance to doxorubicin in breast cancer cells." in: Journal of nutritional science and vitaminology, Vol. 60, Issue 2, pp. 122-8, (2014) (PubMed).

Lim, Shin, Jo, Jyothi, Nguyen, Choi, Kim, Park, Eun, Yoon, Ha, Kim: "Carbonyl reductase 1 is an essential regulator of skeletal muscle differentiation and regeneration." in: The international journal of biochemistry & cell biology, Vol. 45, Issue 8, pp. 1784-93, (2013) (PubMed).

Rashid, Lee, Tak, Lee, Choi, Lee, Kim, Youn, Kang, Ha, Kim: "Carbonyl reductase 1 protects pancreatic β-cells against oxidative stress-induced apoptosis in glucotoxicity and glucolipotoxicity." in: Free radical biology & medicine, Vol. 49, Issue 10, pp. 1522-33, (2010) (PubMed).

Bains, Karkling, Grigliatti, Reid, Riggs: "Two nonsynonymous single nucleotide polymorphisms of human carbonyl reductase 1 demonstrate reduced in vitro metabolism of daunorubicin and doxorubicin." in: Drug metabolism and disposition: the biological fate of chemicals, Vol. 37, Issue 5, pp. 1107-14, (2009) (PubMed).

Lakhman, Chen, Gonzalez-Covarrubias, Schuetz, Blanco: "Functional characterization of the promoter of human carbonyl reductase 1 (CBR1). Role of XRE elements in mediating the induction of CBR1 by ligands of the aryl hydrocarbon receptor." in: Molecular pharmacology, Vol. 72, Issue 3, pp. 734-43, (2007) (PubMed).

Gonzalez-Covarrubias, Ghosh, Lakhman, Pendyala, Blanco: "A functional genetic polymorphism on human carbonyl reductase 1 (CBR1 V88I) impacts on catalytic activity and NADPH binding affinity." in: Drug metabolism and disposition: the biological fate of chemicals, Vol. 35, Issue 6, pp. 973-80, (2007) (PubMed).

Colombe, Vindrios, Michelet, Bernard: "Prostaglandin metabolism in human hair follicle." in: Experimental dermatology, Vol. 16, Issue 9, pp. 762-9, (2007) (PubMed).

Synonyms and alternative names related to CBR1

carbonyl reductase 1 (cbr1), carbonyl reductase 1 (CBR1), carbonyl reductase [NADPH] 1 (LOC100222525), carbonyl reductase 1 S homeolog (cbr1.S), carbonyl reductase (Smp_033530.3), carbonyl reductase [NADPH] 1 (LOC610164), carbonyl reductase 1 (Cbr1), 9-KPR, AW261796, CBR, Cbr, CR, hCBR1, LOC100222525, MGC131152, SDR21C1

Protein level used designations for CBR1

  • carbonyl reductase [NADPH] 1
  • carbonyl reductase 1
  • 15-hydroxyprostaglandin dehydrogenase
  • 20-beta-hydroxysteroid dehydrogenase
  • NADPH-dependent carbonyl reductase 1
  • prostaglandin 9-ketoreductase
  • prostaglandin-E(2) 9-reductase
  • carbonyl reductase
  • carbonyl reductase (NADPH) 1
  • short chain dehydrogenase/reductase family 21C, member 1
  • 20-hydroxysteroid dehydrogenase
  • prostaglandin E(2) 9-keto reductase
  • NADPH:secondary-alcohol oxidoreductase
  • Carbonyl reductase [NADPH] 1 (NADPH-dependent carbonyl reductase 1)
  • Cbr 1
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