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CBFB Proteins

(Core-Binding Factor, beta Subunit (CBFB))

The protein encoded by this gene is the beta subunit of a heterodimeric core-binding transcription factor belonging to the PEBP2/CBF transcription factor family which master-regulates a host of genes specific to hematopoiesis (e.g., RUNX1) and osteogenesis (e.g., RUNX2). The beta subunit is a non-DNA binding regulatory subunit\; it allosterically enhances DNA binding by alpha subunit as the complex binds to the core site of various enhancers and promoters, including murine leukemia virus, polyomavirus enhancer, T-cell receptor enhancers and GM-CSF promoters. Alternative splicing generates two mRNA variants, each encoding a distinct carboxyl terminus. In some cases, a pericentric inversion of chromosome 16 [inv(16)(p13q22)] produces a chimeric transcript consisting of the N terminus of core-binding factor beta in a fusion with the C-terminal portion of the smooth muscle myosin heavy chain 11. This chromosomal rearrangement is associated with acute myeloid leukemia of the M4Eo subtype. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

recommended

CBFB Protein (AA 74-163) (GST tag) (ABIN1348166)

CBFB Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP

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recommended

CBFB Protein (AA 1-182) (GST tag) (ABIN1348164)

CBFB Origin: Human Host: Wheat germ Recombinant WB, ELISA, AA, AP

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recommended

CBFB Protein (ABIN2128359)

CBFB Origin: Human Host: Escherichia coli (E. coli) Recombinant > 85 % pure SDS

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CBFB Proteins by Origin

Find CBFB Proteins for a variety of species such as anti-Human CBFB, anti-Mouse CBFB. The species listed below are among those available. Click on a link to go to the corresponding products.

CBFB Proteins by Source

Here you will find CBFB Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

CBFB Proteins by Protein Type

Here you can find CBFB Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

CBFB Proteins by Application

Find CBFB Proteins validated for a specific application such as WB, SDS, ELISA, AP. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular CBFB Proteins

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

CBFB Protein (AA 74-163) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1348166

Quantity 10 μg

Datasheet Datasheet

CBFB Protein (AA 1-182) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1348164

Quantity 10 μg

Datasheet Datasheet

CBFB Protein

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN2128359

Quantity 50 μg

Datasheet Datasheet

CBFB Protein (AA 1-182) (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7417792

Quantity 100 μg

Datasheet Datasheet

CBFB Protein (AA 1-187) (His tag)

Reactivity Mouse

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7418203

Quantity 100 μg

Datasheet Datasheet

CBFB Protein (AA 1-182) (Strep Tag)

Reactivity Human

Source Tobacco (Nicotiana tabacum)

Validations

Cat. No. ABIN3085782

Quantity 1 mg

Datasheet Datasheet

CBFB Protein (AA 1-187) (Strep Tag)

Reactivity Mouse

Source Tobacco (Nicotiana tabacum)

Validations

Cat. No. ABIN3121502

Quantity 1 mg

Datasheet Datasheet

CBFB Protein (Transcript Variant 2) (Myc-DYKDDDDK Tag)

Reactivity Human

Source HEK-293 Cells

Validations

Cat. No. ABIN2713253

Quantity 20 μg

Datasheet Datasheet

Aliases for CBFB Proteins

core-binding factor beta subunit (CBFB) Proteins
core binding factor beta subunit (Cbfb) Proteins
core-binding factor, beta subunit (cbfb) Proteins
core-binding factor, beta subunit (Cbfb) Proteins
core-binding factor, beta subunit S homeolog (cbfb.S) Proteins
core binding factor beta (Cbfb) Proteins
core-binding factor beta subunit (Cbfb) Proteins
AI893578 Proteins
cbf-beta Proteins
Cbfb Proteins
CBFB Proteins
cbfbeta Proteins
PEA2 Proteins
pea2-beta Proteins
Pebp2 Proteins
pebp2-beta Proteins
PEBP2B Proteins
pebp2b Proteins
PEBP2b Proteins
Pebpb2 Proteins
unp1266 Proteins

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CBFB Proteins by Origin

CBFB Proteins by Source

CBFB Proteins by Protein Type

CBFB Proteins by Application

Popular CBFB Proteins

Aliases for CBFB Proteins

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