C8orf4 Products
(Chromosome 8 Open Reading Frame 4 (C8orf4))
Categories
This gene encodes a small, monomeric, predominantly unstructured protein that functions as a positive regulator of the Wnt\\/beta-catenin signaling pathway. This protein interacts with a repressor of beta-catenin mediated transcription at nuclear speckles. It is thought to competitively block interactions of the repressor with beta-catenin, resulting in up-regulation of beta-catenin target genes. The encoded protein may also play a role in the NF-kappaB and ERK1\\/2 signaling pathways. Expression of this gene may play a role in the proliferation of several types of cancer including thyroid cancer, breast cancer and hematological malignancies. [provided by RefSeq, Nov 2011].
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Featured C8orf4 Categories
C8orf4 Antibodies
High quality antibodies with extensive validation data.
Recommended C8orf4 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human, Mouse, Rat
Application
IHC
Validations
- (3)
Cat. No.
ABIN7262064
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
IHC, ELISA
Validations
- (2)
Cat. No.
ABIN7246439
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF (p), IF (cc), IHC (fro), IHC (p), ICC
Validations
Cat. No.
ABIN2171976
Quantity
100 μL
Datasheet
Datasheet
Recommended C8orf4 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1347664
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our C8orf4 products
: "Immunofluorescence and fluorescent-protein tagging show high correlation for protein localization in mammalian cells." in: Nature methods, Vol. 10, Issue 4, pp. 315-23, (2013) (PubMed).Synonyms and alternative names related to C8orf4
transcriptional and immune response regulator (TCIM), chromosome 22 open reading frame, human C8orf4 (C22H8ORF4), transcriptional and immune response regulator (Tcim), 1110065B09Rik, AW121743, AW321058, C8ORF4, TC-1, TC1Protein level used designations for C8orf4
- human thyroid cancer 1
- thyroid cancer protein 1
- uncharacterized protein C8orf4
- chromosome 8 open reading frame 4
- thyroid cancer-1
- uncharacterized protein C8orf4 homolog
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