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C5AR1 Products

(Complement Component 5a Receptor 1 (C5AR1))

Categories

Receptor for the chemotactic and inflammatory peptide anaphylatoxin C5a. This receptor stimulates chemotaxis, granule enzyme release and superoxide anion production.

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Featured C5AR1 Categories

C5AR1 Antibodies

High quality antibodies with extensive validation data.

C5AR1 ELISA Kits

Reliable ELISA kits for a wide range of species.

C5AR1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended C5AR1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, FACS, ELISA, IHC, IF
Validations
  • (5)
Cat. No. ABIN5539670
Quantity 100 μg
Datasheet Datasheet
Reactivity Cow, Ferret, Human, Rabbit
Application WB, FACS, IHC (p), IP
Validations
  • (3)
  • (2)
Cat. No. ABIN1774738
Quantity 0.1 mg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA
Validations
  • (3)
Cat. No. ABIN513883
Quantity 100 μg
Datasheet Datasheet

Recommended C5AR1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6955019
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Qualitative Cell ELISA
Validations
Cat. No. ABIN1381004
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method
Validations
Cat. No. ABIN417616
Quantity 96 tests
Datasheet Datasheet

Recommended C5AR1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7491549
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1347568
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1347572
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our C5AR1 products

Hornum, Hansen, Tornehave, Fjording, Colmenero, Wätjen, Søe Nielsen, Bliddal, Bartels: "C5a and C5aR are elevated in joints of rheumatoid and psoriatic arthritis patients, and C5aR blockade attenuates leukocyte migration to synovial fluid." in: PLoS ONE, Vol. 12, Issue 12, pp. e0189017, (2018) (PubMed).

Maeda, Kawano, Wada, Yatsuda, Motoshima, Murakami, Kikuchi, Imamura, Eto: "C5aR is frequently expressed in metastatic renal cell carcinoma and plays a crucial role in cell invasion via the ERK and PI3 kinase pathways." in: Oncology reports, Vol. 33, Issue 4, pp. 1844-50, (2015) (PubMed).

Pundir, MacDonald, Kulka: "The Novel Receptor C5aR2 Is Required for C5a-Mediated Human Mast Cell Adhesion, Migration, and Proinflammatory Mediator Production." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 195, Issue 6, pp. 2774-87, (2015) (PubMed).

Spaan, Vrieling, Wallet, Badiou, Reyes-Robles, Ohneck, Benito, de Haas, Day, Jennings, Lina, Vandenesch, van Kessel, Torres, van Strijp, Henry: "The staphylococcal toxins ?-haemolysin AB and CB differentially target phagocytes by employing specific chemokine receptors." in: Nature communications, Vol. 5, pp. 5438, (2014) (PubMed).

Reis, Chen, Sfyroera, Monk, Köhl, Ricklin, Lambris: "C5a receptor-dependent cell activation by physiological concentrations of desarginated C5a: insights from a novel label-free cellular assay." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 189, Issue 10, pp. 4797-805, (2012) (PubMed).

Manthey, Thomas, Shiels, Zernecke, Woodruff, Rolfe, Taylor: "Complement C5a inhibition reduces atherosclerosis in ApoE-/- mice." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 25, Issue 7, pp. 2447-55, (2011) (PubMed).

Camous, Roumenina, Bigot, Brachemi, Frémeaux-Bacchi, Lesavre, Halbwachs-Mecarelli: "Complement alternative pathway acts as a positive feedback amplification of neutrophil activation." in: Blood, Vol. 117, Issue 4, pp. 1340-9, (2011) (PubMed).

Shagdarsuren, Bidzhekov, Mause, Simsekyilmaz, Polakowski, Hawlisch, Gessner, Zernecke, Weber: "C5a receptor targeting in neointima formation after arterial injury in atherosclerosis-prone mice." in: Circulation, Vol. 122, Issue 10, pp. 1026-36, (2010) (PubMed).

Conway Morris, Kefala, Wilkinson, Dhaliwal, Farrell, Walsh, Mackenzie, Reid, Davidson, Haslett, Rossi, Sallenave, Simpson: "C5a mediates peripheral blood neutrophil dysfunction in critically ill patients." in: American journal of respiratory and critical care medicine, Vol. 180, Issue 1, pp. 19-28, (2009) (PubMed).

Baelder, Fuchs, Bautsch, Zwirner, Köhl, Hoymann, Glaab, Erpenbeck, Krug, Braun: "Pharmacological targeting of anaphylatoxin receptors during the effector phase of allergic asthma suppresses airway hyperresponsiveness and airway inflammation." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 174, Issue 2, pp. 783-9, (2005) (PubMed).

Synonyms and alternative names related to C5AR1

complement C5a receptor 1 (C5AR1), complement component 5a receptor 1 (C5ar1), complement C5a receptor 1 (C5ar1), complement component 5a receptor 1 (c5ar1), C5A, C5AR, C5aR, C5R1, C5r1, CD88, Cd88, D7Msu1, GPR77

Protein level used designations for C5AR1

  • C5a anaphylatoxin chemotactic receptor 1
  • C5a anaphylatoxin receptor
  • C5a ligand
  • C5a-R
  • complement component 5 receptor 1
  • complement component 5, receptor 1
  • C5aR
  • complement C5a receptor
  • G protein-coupled receptor 77
  • complement component 5 receptor 1 (C5a ligand)
  • C5a anaphylatoxin chemotactic receptor
  • anaphylatoxin C5a receptor
  • complement component 5a receptor 1
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