C4BPB Products
(Complement Component 4 Binding Protein, beta (C4BPB))
Categories
This gene encodes a member of a superfamily of proteins composed predominantly of tandemly arrayed short consensus repeats of approximately 60 amino acids. A single, unique beta-chain encoded by this gene assembles with seven identical alpha-chains into the predominant isoform of C4b-binding protein, a multimeric protein that controls activation of the complement cascade through the classical pathway. C4b-binding protein has a regulatory role in the coagulation system also, mediated through the beta-chain binding of protein S, a vitamin K-dependent protein that serves as a cofactor of activated protein C. The genes encoding both alpha and beta chains are located adjacent to each other on human chromosome 1 in the regulator of complement activation gene cluster. Alternative splicing gives rise to multiple transcript variants. [provided by RefSeq, Jul 2008].
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Featured C4BPB Categories
C4BPB Antibodies
High quality antibodies with extensive validation data.
C4BPB ELISA Kits
Reliable ELISA kits for a wide range of species.
C4BPB Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended C4BPB Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IP
Validations
- (1)
- (3)
Cat. No.
ABIN513876
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
IHC, IF
Validations
- (3)
Cat. No.
ABIN7011062
Quantity
60 μL
Datasheet
Datasheet
Reactivity
Human
Application
IHC, ELISA, IP
Validations
- (3)
Cat. No.
ABIN7146168
Quantity
100 μL
Datasheet
Datasheet
Recommended C4BPB ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6965287
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6962013
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6955009
Quantity
96 tests
Datasheet
Datasheet
Recommended C4BPB Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1347544
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN2128238
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7391957
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our C4BPB products
: "Serum amyloid A, protein Z, and C4b-binding protein β chain as new potential biomarkers for pulmonary tuberculosis." in: PLoS ONE, Vol. 12, Issue 3, pp. e0173304, (2017) (PubMed).: "The surface layer of Tannerella forsythia contributes to serum resistance and oral bacterial coaggregation." in: Infection and immunity, Vol. 81, Issue 4, pp. 1198-206, (2013) (PubMed).
: "Characterization of the ovine complement 4 binding protein-beta (C4BPB) chain as a serum biomarker for enhanced diagnosis of sheep scab." in: Molecular and cellular probes, Vol. 27, Issue 3-4, pp. 158-63, (2013) (PubMed).
: "Real-time reverse transcription-polymerase chain reaction assay for SARS-associated coronavirus." in: Emerging infectious diseases, Vol. 10, Issue 2, pp. 311-6, (2004) (PubMed).
Synonyms and alternative names related to C4BPB
complement component 4 binding protein beta (C4BPB), complement component 4 binding protein, beta (C4bpb), C4BP, C4bp-ps1, C4BPBProtein level used designations for C4BPB
- complement component 4 binding protein, beta
- complement component 4 binding protein, beta chain
- C4b-binding protein beta chain
- complement component 4-binding protein, beta
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