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C3 Products

(Complement Component 3 (C3))

Categories

Complement component C3 plays a central role in the activation of complement system. Its activation is required for both classical and alternative complement activation pathways. People with C3 deficiency are susceptible to bacterial infection. [provided by RefSeq, Feb 2009].

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Featured C3 Categories

C3 Antibodies

High quality antibodies with extensive validation data.

C3 ELISA Kits

Reliable ELISA kits for a wide range of species.

C3 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended C3 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (6)
Cat. No. ABIN7432772
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, ELISA, IHC (fro), IF (p), IHC (p)
Validations
  • (3)
  • (3)
Cat. No. ABIN681913
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC (p)
Validations
  • (4)
Cat. No. ABIN560117
Quantity 100 μg
Datasheet Datasheet

Recommended C3 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (6)
  • (1)
Cat. No. ABIN6955003
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6962850
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6955004
Quantity 96 tests
Datasheet Datasheet

Recommended C3 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7274036
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source HEK-293 Cells
Validations
  • (2)
Cat. No. ABIN7274037
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7320494
Quantity 50 μg
Datasheet Datasheet

Latest Publications for our C3 products

Zheng, Liang, Xu, Yang, Feng, Shen, Zhong, Wu, Shu, Sun, Xu: "Complement component 3 prevents imiquimod-induced psoriatic skin inflammation by inhibiting apoptosis in mice." in: International immunopharmacology, Vol. 85, pp. 106692, (2020) (PubMed).

Walter, Monthoux, Fortes, Grossmann, Roschitzki, Meili, Riond, Hofmann-Lehmann, Naegeli, Bleul: "The bovine cumulus proteome is influenced by maturation condition and maturational competence of the oocyte." in: Scientific reports, Vol. 10, Issue 1, pp. 9880, (2020) (PubMed).

Fernández-Vega Cueto, Álvarez, García, Artime, Álvarez Barrios, Rodríguez-Uña, Coca-Prados, González-Iglesias: "Systemic Alterations of Immune Response-Related Proteins during Glaucoma Development in the Murine Model DBA/2J." in: Diagnostics (Basel, Switzerland), Vol. 10, Issue 6, (2020) (PubMed).

Zhang, Wang, Wang, Jin, Zhao, Xiong, Zhang, Mou, Li, Yang, Dai: "Generation of complement protein C3 deficient pigs by CRISPR/Cas9-mediated gene targeting." in: Scientific reports, Vol. 7, Issue 1, pp. 5009, (2019) (PubMed).

Neglia, Oggioni, Mercurio, De Simoni, Fumagalli: "Specific contribution of mannose-binding lectin murine isoforms to brain ischemia/reperfusion injury." in: Cellular & molecular immunology, (2019) (PubMed).

Wu, Dejanovic, Gandham, Gogineni, Edmonds, Schauer, Srinivasan, Huntley, Wang, Wang, Hedehus, Barck, Stark, Ngu, Foreman, Meilandt, Elstrott, Chang, Hansen, Carano, Sheng, Hanson: "Complement C3 Is Activated in Human AD Brain and Is Required for Neurodegeneration in Mouse Models of Amyloidosis and Tauopathy." in: Cell reports, Vol. 28, Issue 8, pp. 2111-2123.e6, (2019) (PubMed).

Shen, Zhang, Feng, Chen, Li, Iqbal, Liao, Zhao, Zhai: "iTRAQ-Based Proteomic Analysis Reveals Protein Profile in Plasma from Children with Autism." in: Proteomics. Clinical applications, Vol. 12, Issue 3, pp. e1700085, (2019) (PubMed).

Thomas, Risalde, Serrano, Sevilla, Geijo, Ortíz, Fuertes, Ruíz-Fons, de la Fuente, Domínguez, Juste, Garrido, Gortázar: "The response of red deer to oral administration of heat-inactivated Mycobacterium bovis and challenge with a field strain." in: Veterinary microbiology, Vol. 208, pp. 195-202, (2018) (PubMed).

Batchu, Dugbartey, Wadosky, Mickelsen, Ko, Wood, Zhao, Yang, Fowell, Korshunov: "Innate Immune Cells Are Regulated by Axl in Hypertensive Kidney." in: The American journal of pathology, Vol. 188, Issue 8, pp. 1794-1806, (2018) (PubMed).

Zhang, Huang, Jing, Fu, Yuan, Xia, Cai, Gan, Chen, Zou, Long, Wang, Wang, Xu: "SAK-HV Triggered a Short-period Lipid-lowering Biotherapy Based on the Energy Model of Liver Proliferation via a Novel Pathway." in: Theranostics, Vol. 7, Issue 6, pp. 1749-1769, (2018) (PubMed).

Synonyms and alternative names related to C3

complement C3 (C3), complement component 3 (C3), complement component c3a, duplicate 1 (c3a.1), complement component 3 L homeolog (c3.L), complement C3 (LOC443475), complement component 3 (c3), complement component C3 (c3-1), complement C3-like (LOC100060539), AHUS5, AI255234, ARMD9, ASP, asp, C3, c3, C3-1, C3a, C3b, C3d, CPAMD1, cpamd1, HSE-MSF, Plp, sb:cb26, si:dkey-76b14.4, wu:fi34b03, wu:fj86e11

Protein level used designations for C3

  • C3 and PZP-like alpha-2-macroglobulin domain-containing protein 1
  • C3a anaphylatoxin
  • acylation-stimulating protein cleavage product
  • complement C3
  • complement component C3
  • complement component C3a
  • complement component C3b
  • prepro-C3
  • acylation stimulating protein
  • complement component 3d
  • complement factor 3
  • cb26
  • complement component 3
  • complement C3 alpha chain
  • complement component C3d
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