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C1QA Products

(Complement Component 1, Q Subcomponent, A Chain (C1QA))

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This gene encodes a major constituent of the human complement subcomponent C1q. C1q associates with C1r and C1s in order to yield the first component of the serum complement system. Deficiency of C1q has been associated with lupus erythematosus and glomerulonephritis. C1q is composed of 18 polypeptide chains: six A-chains, six B-chains, and six C-chains. Each chain contains a collagen-like region located near the N terminus and a C-terminal globular region. The A-, B-, and C-chains are arranged in the order A-C-B on chromosome 1. This gene encodes the A-chain polypeptide of human complement subcomponent C1q. [provided by RefSeq, Jul 2008].

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Featured C1QA Categories

C1QA Antibodies

High quality antibodies with extensive validation data.

C1QA ELISA Kits

Reliable ELISA kits for a wide range of species.

C1QA Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended C1QA Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Application WB, IHC, IP, ICC
Validations
  • (6)
Cat. No. ABIN7440998
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ELISA, ICC, FACS
Validations
  • (6)
Cat. No. ABIN5542307
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (5)
Cat. No. ABIN7435415
Quantity 100 μL
Datasheet Datasheet

Recommended C1QA ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6965999
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6965998
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6954994
Quantity 96 tests
Datasheet Datasheet

Recommended C1QA Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
  • (1)
Cat. No. ABIN1347366
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7397291
Quantity 100 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7414732
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our C1QA products

Achieng, Guyah, Cheng, Ongecha, Ouma, Lambert, Perkins: "Molecular basis of reduced LAIR1 expression in childhood severe malarial anaemia: Implications for leukocyte inhibitory signalling." in: EBioMedicine, (2019) (PubMed).

Deng, Xu, Fang, Yu, Zhu, Chen, Liu, Zhou: "The Surface-Exposed Protein SntA Contributes to Complement Evasion in Zoonotic Streptococcus suis." in: Frontiers in immunology, Vol. 9, pp. 1063, (2018) (PubMed).

Bally, Ancelet, Moriscot, Gonnet, Mantovani, Daniel, Schoehn, Arlaud, Thielens: "Expression of recombinant human complement C1q allows identification of the C1r/C1s-binding sites." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 110, Issue 21, pp. 8650-5, (2013) (PubMed).

Hinton, Xiong, Johlfs, Tang, Keller, Tsurushita: "An engineered human IgG1 antibody with longer serum half-life." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 176, Issue 1, pp. 346-56, (2005) (PubMed).

Steegmaier, Yang, Yoo, Huang, Shen, Yu, Luo, Scheller: "Three novel proteins of the syntaxin/SNAP-25 family." in: The Journal of biological chemistry, Vol. 273, Issue 51, pp. 34171-9, (1999) (PubMed).

Thoreau, Bergès, Callebaut, Guillier-Gencik, Gressin, Bernheim, Karst, Mornon, Kitzis, Chomel: "Molecular cloning, expression analysis, and chromosomal localization of human syntaxin 8 (STX8)." in: Biochemical and biophysical research communications, Vol. 257, Issue 2, pp. 577-83, (1999) (PubMed).

Sellar, Blake, Reid: "Characterization and organization of the genes encoding the A-, B- and C-chains of human complement subcomponent C1q. The complete derived amino acid sequence of human C1q." in: The Biochemical journal, Vol. 274 ( Pt 2), pp. 481-90, (1991) (PubMed).

Synonyms and alternative names related to C1QA

complement C1q A chain (C1QA), complement component 1, q subcomponent, A chain (c1qa), complement C1q A chain (C1qa), complement component 1, q subcomponent, alpha polypeptide (C1qa), AI255395, C1q, C1QA, zgc:109903

Protein level used designations for C1QA

  • complement component 1, q subcomponent, alpha polypeptide
  • complement C1q subcomponent subunit A
  • complement component 1, q subcomponent, A chain
  • complement component C1q, A chain
  • complement C1qA
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