C1q Products
(Complement Fragment C1q (C1q))
Categories
C1q associates with the proenzymes C1r and C1s to yield C1, the first component of the serum complement system. The collagen-like regions of C1q interact with the Ca(2+)-dependent C1r(2)C1s(2) proenzyme complex, and efficient activation of C1 takes place on interaction of the globular heads of C1q with the Fc regions of IgG or IgM antibody present in immune complexes.
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Featured C1q Categories
C1q Antibodies
High quality antibodies with extensive validation data.
C1q ELISA Kits
Reliable ELISA kits for a wide range of species.
C1q Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended C1q Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Application
FACS, IHC (fro), IF, Func
Validations
- (3)
Cat. No.
ABIN2191846
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Application
IHC (fro)
Validations
- (3)
Cat. No.
ABIN2477784
Quantity
1 mL
Datasheet
Datasheet
Reactivity
Mouse
Application
FACS, IA
Validations
- (5)
Cat. No.
ABIN2191787
Quantity
100 μg
Datasheet
Datasheet
Recommended C1q ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (3)
- (1)
Cat. No.
ABIN6955043
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6999543
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6955044
Quantity
96 tests
Datasheet
Datasheet
Recommended C1q Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Latest Publications for our C1q products
: "CXCL4 suppresses tolerogenic immune signature of monocyte-derived dendritic cells." in: European journal of immunology, Vol. 50, Issue 10, pp. 1598-1601, (2021) (PubMed).: "Complement activation profile of patients with primary focal segmental glomerulosclerosis." in: PLoS ONE, Vol. 15, Issue 6, pp. e0234934, (2020) (PubMed).
: "The role of complement components C1q, MBL and C1 inhibitor in pathogenesis of endometriosis." in: Archives of gynecology and obstetrics, Vol. 297, Issue 6, pp. 1495-1501, (2018) (PubMed).
: "Acute and prolonged complement activation in the central nervous system during herpes simplex encephalitis." in: Journal of neuroimmunology, Vol. 295-296, pp. 130-8, (2016) (PubMed).
: "Complement activation contributes to the injury and outcome of kidney in human anti-glomerular basement membrane disease." in: Journal of clinical immunology, Vol. 33, Issue 1, pp. 172-8, (2013) (PubMed).
: "Selectivity analysis of single binder assays used in plasma protein profiling." in: Proteomics, Vol. 13, Issue 23-24, pp. 3406-10, (2013) (PubMed).
: "Variance decomposition of protein profiles from antibody arrays using a longitudinal twin model." in: Proteome science, Vol. 9, pp. 73, (2011) (PubMed).
: "Complement protein C1q forms a complex with cytotoxic prion protein oligomers." in: The Journal of biological chemistry, Vol. 285, Issue 25, pp. 19267-76, (2010) (PubMed).
: "Therapeutic targeting of classical and lectin pathways of complement protects from ischemia-reperfusion-induced renal damage." in: The American journal of pathology, Vol. 176, Issue 4, pp. 1648-59, (2010) (PubMed).
: "B cells produce pathogenic antibodies and impair recovery after spinal cord injury in mice." in: The Journal of clinical investigation, Vol. 119, Issue 10, pp. 2990-9, (2009) (PubMed).
Synonyms and alternative names related to C1q
complement component 1, q subcomponent, alpha polypeptide (C1qa), AI255395, C1qProtein level used designations for C1q
- complement C1q subcomponent subunit A
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