C10orf2 Products
(Chromosome 10 Open Reading Frame 2 (C10ORF2))
Categories
This gene encodes a hexameric DNA helicase which unwinds short stretches of double-stranded DNA in the 5' to 3' direction and, along with mitochondrial single-stranded DNA binding protein and mtDNA polymerase gamma, is thought to play a key role in mtDNA replication. The protein localizes to the mitochondrial matrix and mitochondrial nucleoids. Mutations in this gene cause infantile onset spinocerebellar ataxia (IOSCA) and progressive external ophthalmoplegia (PEO) and are also associated with several mitochondrial depletion syndromes. Alternative splicing results in multiple transcript variants encoding distinct isoforms.[provided by RefSeq, Aug 2009].
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Featured C10orf2 Categories
C10orf2 Antibodies
High quality antibodies with extensive validation data.
C10orf2 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended C10orf2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Cow, Dog, Guinea Pig, Horse, Human, Mouse, Rabbit, Rat, Zebrafish (Danio rerio)
Application
WB
Validations
- (2)
- (2)
- (2)
Cat. No.
ABIN2775251
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IHC
Validations
- (3)
Cat. No.
ABIN7173941
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, ELISA, IHC
Validations
- (2)
Cat. No.
ABIN6260353
Quantity
100 μL
Datasheet
Datasheet
Recommended C10orf2 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1347017
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1347016
Quantity
25 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7422814
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our C10orf2 products
: "Impaired p32 regulation caused by the lymphoma-prone RECQ4 mutation drives mitochondrial dysfunction." in: Cell reports, Vol. 7, Issue 3, pp. 848-58, (2014) (PubMed).: "High mitochondrial DNA copy number has detrimental effects in mice." in: Human molecular genetics, Vol. 19, Issue 13, pp. 2695-705, (2010) (PubMed).
Synonyms and alternative names related to C10orf2
twinkle mtDNA helicase L homeolog (twnk.L), twinkle mtDNA helicase (TWNK), twinkle mtDNA helicase (Twnk), ATXN8, C6H10orf2, D19Ertd626e, IOSCA, MTDPS7, PEO, PEO1, PEOA3, SANDO, SCA8, TWINL, TwinlProtein level used designations for C10orf2
- uncharacterized protein LOC414487
- twinkle protein, mitochondrial
- T7 gp4-like protein with intramitochondrial nucleoid localization
- T7 helicase-related protein with intramitochondrial nucleoid localization
- T7-like mitochondrial DNA helicase
- ataxin 8
- mitochondrial twinkle protein
- progressive external ophthalmoplegia 1 protein
- progressive external ophthalmoplegia 1
- progressive external ophthalmoplegia 1 homolog
- progressive external ophthalmoplegia 1 protein homolog
Did you look for something else?
- C10ORF129
- C10orf126
- C10ORF120
- C10orf118
- C10ORF111
- C10orf105
- C10orf10
- C10H14ORF53
- C-Type Lectin Domain Family 6, Member A
- C-Type Lectin Domain Family 4, Member M
- C-Type Lectin Domain Family 2, Member I
- C-Type Lectin Domain Family 2, Member H
- C-type lectin domain family 2 member D-related protein
- C-Type Lectin Domain Family 1, Member B
- c-Rel
- C-Raf Proto-Oncogene Serine/Threonine Protein Kinase
- C-Peptide
- c-MET
- C-JUN
- c-FOS
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