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c-MET Products

(Met Proto-Oncogene (MET))

Categories

The proto-oncogene MET product is the hepatocyte growth factor receptor and encodes tyrosine-kinase activity. The primary single chain precursor protein is post-translationally cleaved to produce the alpha and beta subunits, which are disulfide linked to form the mature receptor. Various mutations in the MET gene are associated with papillary renal carcinoma. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].

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Featured c-MET Categories

c-MET Antibodies

High quality antibodies with extensive validation data.

c-MET ELISA Kits

Reliable ELISA kits for a wide range of species.

c-MET Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended c-MET Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse
Application WB, ELISA, IHC (p), FACS, IF (cc), IF (p), IHC (fro)
Validations
  • (5)
  • (5)
Cat. No. ABIN671661
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, FACS, ICC
Validations
  • (7)
Cat. No. ABIN5542707
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, ICC, IP
Validations
  • (5)
Cat. No. ABIN7434734
Quantity 100 μL
Datasheet Datasheet

Recommended c-MET ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Analytical Method Semi-Quantitative Sandwich ELISA
Validations
  • (5)
Cat. No. ABIN625228
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Semi-Quantitative Sandwich ELISA
Validations
  • (4)
Cat. No. ABIN5680031
Quantity 96 tests
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Analytical Method Semi-Quantitative Sandwich ELISA
Validations
  • (4)
Cat. No. ABIN625241
Quantity 96 tests
Datasheet Datasheet

Recommended c-MET Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (5)
Cat. No. ABIN7275248
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (4)
Cat. No. ABIN7275247
Quantity 100 μg
Datasheet Datasheet
Reactivity Cynomolgus
Source HEK-293 Cells
Validations
  • (3)
Cat. No. ABIN7275246
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our c-MET products

Mahameed, Boukeileh, Obiedat, Darawshi, Dipta, Rimon, McLennan, Fassler, Reichmann, Karni, Preisinger, Wilhelm, Huber, Tirosh: "Pharmacological induction of selective endoplasmic reticulum retention as a strategy for cancer therapy." in: Nature communications, Vol. 11, Issue 1, pp. 1304, (2020) (PubMed).

Mahameed, Wilhelm, Darawshi, Obiedat, Tommy, Chintha, Schubert, Samali, Chevet, Eriksson, Huber, Tirosh: "The unfolded protein response modulators GSK2606414 and KIRA6 are potent KIT inhibitors." in: Cell death & disease, Vol. 10, Issue 4, pp. 300, (2020) (PubMed).

Yoo, Lee, Jung, Han, Lee, Han, Kim, Chae, Ryu, Chung: "Machine Learning-Guided Prediction of Antigen-Reactive In Silico Clonotypes Based on Changes in Clonal Abundance through Bio-Panning." in: Biomolecules, Vol. 10, Issue 3, (2020) (PubMed).

Novo, Heath, Mitchell, Caligiuri, MacFarlane, Reijmer, Charlton, Knight, Calka, McGhee, Dornier, Sumpton, Mason, Echard, Klinkert, Secklehner, Kruiswijk, Vousden, Macpherson, Blyth, Bailey, Yin et al.: "Mutant p53s generate pro-invasive niches by influencing exosome podocalyxin levels. ..." in: Nature communications, Vol. 9, Issue 1, pp. 5069, (2019) (PubMed).

Penchev, Chang, Begum, Ewachiw, Gocke, Li, McMillan, Wang, Anders, Marchionni, Maitra, Uren, Rasheed, Matsui: "Ezrin Promotes Stem Cell Properties in Pancreatic Ductal Adenocarcinoma." in: Molecular cancer research : MCR, Vol. 17, Issue 4, pp. 929-936, (2019) (PubMed).

Stringer, Day, DSouza, Jamieson, Ensbey, Bruce, Lim, Goasdoué, Offenhäuser, Akgül, Allan, Robertson, Lucas, Tollesson, Campbell, Winter, Do, Dobrovic, Inglis, Jeffree, Johns, Boyd: "A reference collection of patient-derived cell line and xenograft models of proneural, classical and mesenchymal glioblastoma." in: Scientific reports, Vol. 9, Issue 1, pp. 4902, (2019) (PubMed).

Graves-Deal, Bogatcheva, Rehman, Lu, Higginbotham, Singh: "Broad-spectrum receptor tyrosine kinase inhibitors overcome de novo and acquired modes of resistance to EGFR-targeted therapies in colorectal cancer." in: Oncotarget, Vol. 10, Issue 13, pp. 1320-1333, (2019) (PubMed).

Li, Dick, Lu, Zhang, Sun: "Induction of MET Receptor Tyrosine Kinase Down-regulation through Antibody-mediated Receptor Clustering." in: Scientific reports, Vol. 9, Issue 1, pp. 1988, (2019) (PubMed).

Jo, Lee, Lee, Park, Park, Choi, Hong, Kim: "Combination therapy with c-met inhibitor and TRAIL enhances apoptosis in dedifferentiated liposarcoma patient-derived cells." in: BMC cancer, Vol. 19, Issue 1, pp. 496, (2019) (PubMed).

Ma, Zhang, Wang, Huang, Kuai, Zhu, Chen, Jia, Feng, Tang, Liu: "High-Affinity Human Anti-c-Met IgG Conjugated to Oxaliplatin as Targeted Chemotherapy for Hepatocellular Carcinoma." in: Frontiers in oncology, Vol. 9, pp. 717, (2019) (PubMed).

Synonyms and alternative names related to c-MET

MET proto-oncogene, receptor tyrosine kinase (MET), met proto-oncogene (Met), MET proto-oncogene, receptor tyrosine kinase (Met), MET proto-oncogene, receptor tyrosine kinase L homeolog (met.L), AI838057, AUTS9, c-Met, c-met, C-MET, HGF, HGFR, Hgfr, MET, met, met-A, Par4, RCCP2

Protein level used designations for c-MET

  • HGF receptor
  • HGF/SF receptor
  • SF receptor
  • hepatocyte growth factor receptor
  • met proto-oncogene tyrosine kinase
  • proto-oncogene c-Met
  • scatter factor receptor
  • tyrosine-protein kinase Met
  • c-Met
  • hepatocyte growth factor receptor-like
  • met proto-oncogene
  • Proto-oncogene c-Met
  • Scatter factor receptor
  • Tyrosine-protein kinase Met
  • Hepatocyte growth factor receptor
  • HGF receptor c-Met
  • proto-oncogene, receptor tyrosine kinase
  • tyrosine kinase
  • met proto-oncogene (hepatocyte growth factor receptor)
  • MET proto-oncogene, receptor tyrosine kinase L homeolog
  • c-met/hepatocyte growth factor receptor
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