Caveolin-1 Products
(Caveolin 1, Caveolae Protein, 22kDa (CAV1))
Categories
The scaffolding protein encoded by this gene is the main component of the caveolae plasma membranes found in most cell types. The protein links integrin subunits to the tyrosine kinase FYN, an initiating step in coupling integrins to the Ras-ERK pathway and promoting cell cycle progression. The gene is a tumor suppressor gene candidate and a negative regulator of the Ras-p42/44 mitogen-activated kinase cascade. Caveolin 1 and caveolin 2 are located next to each other on chromosome 7 and express colocalizing proteins that form a stable hetero-oligomeric complex. Mutations in this gene have been associated with Berardinelli-Seip congenital lipodystrophy. Alternatively spliced transcripts encode alpha and beta isoforms of caveolin 1.[provided by RefSeq, Mar 2010].
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Featured Caveolin-1 Categories
Caveolin-1 Antibodies
High quality antibodies with extensive validation data.
Caveolin-1 ELISA Kits
Reliable ELISA kits for a wide range of species.
Caveolin-1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Caveolin-1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IF, IP, IHC (p), ICC
Validations
- (1)
- (7)
Cat. No.
ABIN2854651
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (7)
Cat. No.
ABIN7431320
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (8)
Cat. No.
ABIN7431323
Quantity
100 μL
Datasheet
Datasheet
Recommended Caveolin-1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (7)
- (1)
Cat. No.
ABIN6954474
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6954475
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Dog
Analytical Method
Quantitative Sandwich ELISA
Validations
- (2)
- (1)
Cat. No.
ABIN6954472
Quantity
96 tests
Datasheet
Datasheet
Recommended Caveolin-1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (4)
- (1)
Cat. No.
ABIN1348146
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Mammalian Cells
Validations
- (2)
Cat. No.
ABIN7538162
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7122185
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our Caveolin-1 products
: "Twist1-induced miR-199a-3p promotes liver fibrosis by suppressing caveolin-2 and activating TGF-β pathway." in: Signal transduction and targeted therapy, Vol. 5, Issue 1, pp. 75, (2021) (PubMed).: "A novel c-Kit/phospho-prohibitin axis enhances ovarian cancer stemness and chemoresistance via Notch3-PBX1 and β-catenin-ABCG2 signaling." in: Journal of biomedical science, Vol. 27, Issue 1, pp. 42, (2020) (PubMed).
: "Endothelium-dependent hyperpolarization-mediated vasodilatation compensates nitric oxide-mediated endothelial dysfunction during ischemia in diabetes-induced canine coronary collateral ..." in: Microcirculation (New York, N.Y. : 1994), Vol. 25, Issue 5, pp. e12456, (2019) (PubMed).
: "Basigin can be a therapeutic target to restore the retinal vascular barrier function in the mouse model of diabetic retinopathy." in: Scientific reports, Vol. 6, pp. 38445, (2018) (PubMed).
: "Tissue damage negatively regulates LPS-induced macrophage necroptosis." in: Cell death and differentiation, Vol. 23, Issue 9, pp. 1428-47, (2018) (PubMed).
: "Swim Training Modulates Skeletal Muscle Energy Metabolism, Oxidative Stress, and Mitochondrial Cholesterol Content in Amyotrophic Lateral Sclerosis Mice." in: Oxidative medicine and cellular longevity, Vol. 2018, pp. 5940748, (2018) (PubMed).
: "Expression of Stromal Caveolin- 1 May Be a Predictor for Aggressive Behaviour of Breast Cancer." in: Pathology oncology research : POR, (2017) (PubMed).
: "Caveolin-1 protects against hepatic ischemia/reperfusion injury through ameliorating peroxynitrite-mediated cell death." in: Free radical biology & medicine, Vol. 95, pp. 209-15, (2017) (PubMed).
: "Paracrine effects of human adipose-derived mesenchymal stem cells in inflammatory stress-induced senescence features of osteoarthritic chondrocytes." in: Aging, Vol. 8, Issue 8, pp. 1703-17, (2017) (PubMed).
: "A preliminary study on the interaction between Asn-Gly-Arg (NGR)-modified multifunctional nanoparticles and vascular epithelial cells." in: Acta pharmaceutica Sinica. B, Vol. 7, Issue 3, pp. 361-372, (2017) (PubMed).
Synonyms and alternative names related to Caveolin-1
caveolin 1 (cav1), caveolin 1 L homeolog (cav1.L), caveolin 1 S homeolog (cav1.S), caveolin 1 (CAV1), caveolin 1, caveolae protein (Cav1), caveolin 1 (Cav1), caveolin 1, caveolae protein, 22kDa (CAV1), Caveolin (cav-1), bscl3, BSCL3, cav, Cav, Cav-1, cav-1, cav1, CAV1, cav1a, cav1b, caveolin-1, Caveolin-1, caveolin 1, cgl3, CGL3, fc07c04, mstp085, MSTP085, PPH3, vip21, VIP21, wu:fc07c04Protein level used designations for Caveolin-1
- caveolin-1
- caveolin 1
- caveolin, caveolae protein 1
- caveolin, caveolae protein, 22 kDa
- caveolin caveolae protein 22 kDa
- vesicular integral-membrane protein VIP21
- cell growth-inhibiting protein 32
- testis derived transcript
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