Cathepsin L1 Products
(Cathepsin L1 (CTSL1))
Categories
The protein encoded by this gene is a lysosomal cysteine proteinase that plays a major role in intracellular protein catabolism. Its substrates include collagen and elastin, as well as alpha-1 protease inhibitor, a major controlling element of neutrophil elastase activity. The encoded protein has been implicated in several pathologic processes, including myofibril necrosis in myopathies and in myocardial ischemia, and in the renal tubular response to proteinuria. This protein, which is a member of the peptidase C1 family, is a dimer composed of disulfide-linked heavy and light chains, both produced from a single protein precursor. Multiple alternatively spliced transcript variants have been found for this gene. [provided by RefSeq, Apr 2012].
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Featured Cathepsin L1 Categories
Cathepsin L1 Antibodies
High quality antibodies with extensive validation data.
Cathepsin L1 ELISA Kits
Reliable ELISA kits for a wide range of species.
Cathepsin L1 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Cathepsin L1 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Application
WB, IHC, IP, ICC
Validations
- (1)
- (6)
Cat. No.
ABIN7431587
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Pig, Rat
Application
WB, ELISA, IF (cc), IF (p), IHC (p), IHC (fro)
Validations
- (1)
- (5)
Cat. No.
ABIN687532
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, IHC
Validations
- (3)
Cat. No.
ABIN7239770
Quantity
200 μL
Datasheet
Datasheet
Recommended Cathepsin L1 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (2)
- (1)
Cat. No.
ABIN6954461
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6954463
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6962834
Quantity
96 tests
Datasheet
Datasheet
Recommended Cathepsin L1 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (1)
Cat. No.
ABIN7122182
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1350727
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1350725
Quantity
10 μg
Datasheet
Datasheet
Latest Publications for our Cathepsin L1 products
: "COVID-19 receptor and malignant cancers: Association of CTSL expression with susceptibility to SARS-CoV-2." in: International journal of biological sciences, Vol. 18, Issue 6, pp. 2362-2371, (2022) (PubMed).: "Immune-mediated ECM depletion improves tumour perfusion and payload delivery. ..." in: EMBO molecular medicine, Vol. 11, Issue 12, pp. e10923, (2020) (PubMed).
: "African Swine Fever Virus Undergoes Outer Envelope Disruption, Capsid Disassembly and Inner Envelope Fusion before Core Release from Multivesicular Endosomes." in: PLoS pathogens, Vol. 12, Issue 4, pp. e1005595, (2016) (PubMed).
: "Cathepsin L inactivation leads to multimodal inhibition of prostate cancer cell dissemination in a preclinical bone metastasis model." in: International journal of cancer, Vol. 138, Issue 11, pp. 2665-77, (2016) (PubMed).
: "Urinary proteins induce lysosomal membrane permeabilization and lysosomal dysfunction in renal tubular epithelial cells." in: American journal of physiology. Renal physiology, Vol. 308, Issue 6, pp. F639-49, (2015) (PubMed).
: "Stress-resistant Translation of Cathepsin L mRNA in Breast Cancer Progression." in: The Journal of biological chemistry, Vol. 290, Issue 25, pp. 15758-69, (2015) (PubMed).
: "Biochemical and clinical correlation of intraplaque neovascularization using contrast-enhanced ultrasound of the carotid artery." in: Atherosclerosis, Vol. 233, Issue 2, pp. 579-83, (2014) (PubMed).
: "Anti-serpin antibody-mediated regulation of proteases in autoimmune diabetes." in: The Journal of biological chemistry, Vol. 288, Issue 3, pp. 1612-9, (2013) (PubMed).
: "The ubiquitin ligase Mindbomb 1 coordinates gastrointestinal secretory cell maturation." in: The Journal of clinical investigation, Vol. 123, Issue 4, pp. 1475-91, (2013) (PubMed).
: "Transient expression of progesterone receptor and cathepsin-l in human granulosa cells during the periovulatory period." in: Fertility and sterility, Vol. 97, Issue 3, pp. 707-13.e1, (2012) (PubMed).
Synonyms and alternative names related to Cathepsin L1
cathepsin L (CTSL), cathepsin L (Ctsl), cathepsin V (CTSV), cathepsin L L homeolog (ctsl.L), cathepsin L (ctsl), cathepsin L1 (LOC100008830), Cathepsin L1 (catl1), cathepsin L (26-29-p), Cathepsin L (catl), cathepsin L1 (Tsp_11596), testin gene (Testin), cathepsin 12 (cts12), cathepsin L1 (LOC102156614), cathepsin Lb (ctslb), cathepsin L.1 (ctsl.1), 26-29-p, 1190035F06Rik, CATHL, CATL, CatL, catl, catL, cb15, Cp1, cpl-1, Ctsl, CTSL, ctsl, CTSL1, Ctsl1, ctsl1b, CTSV, fs, hgg1, LOC663234, MEP, mep, MGC80629, MGC107932, nkt, si:dkey-121a11.6, wu:fb30g09, zgc:92089Protein level used designations for Cathepsin L1
- cathepsin L1
- major excreted protein
- Cat L
- furless
- nackt
- p39 cysteine proteinase
- CP-2
- MEP
- cathepsin L
- cyclic protein 2
- Cathepsin L1
- cathepsin L1-like
- 26-29kD-proteinase
- cysteine proteinase-1
- Cathepsin L
- CMB-23
- testin-2
- cathepsin V
- cathepsin L, 1 b
- cathepsin L, b
- cathepsin Lb
- cstlb
- hatching gland 1
- hatching gland gene 1
- cathepsin L.1
- ctslc
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