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Cathepsin K Products

(Cathepsin K (CTSK))

Categories

The protein encoded by this gene is a lysosomal cysteine proteinase involved in bone remodeling and resorption. This protein, which is a member of the peptidase C1 protein family, is predominantly expressed in osteoclasts. However, the encoded protein is also expressed in a significant fraction of human breast cancers, where it could contribute to tumor invasiveness. Mutations in this gene are the cause of pycnodysostosis, an autosomal recessive disease characterized by osteosclerosis and short stature. [provided by RefSeq, Apr 2013].

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Featured Cathepsin K Categories

Cathepsin K Antibodies

High quality antibodies with extensive validation data.

Cathepsin K ELISA Kits

Reliable ELISA kits for a wide range of species.

Cathepsin K Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Cathepsin K Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, ICC, IHC (p), IHC (fro)
Validations
  • (7)
Cat. No. ABIN7441856
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application IHC, StM
Validations
  • (6)
Cat. No. ABIN6939219
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC (p)
Validations
  • (1)
  • (4)
Cat. No. ABIN514786
Quantity 100 μg
Datasheet Datasheet

Recommended Cathepsin K ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (3)
  • (6)
Cat. No. ABIN6574151
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6954458
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (3)
  • (1)
Cat. No. ABIN6954460
Quantity 96 tests
Datasheet Datasheet

Recommended Cathepsin K Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7122181
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1350723
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1350722
Quantity 25 μg
Datasheet Datasheet

Latest Publications for our Cathepsin K products

Zhou, Yang, Yin, Gu, Xu, Liang: "Compound K induces neurogenesis of neural stem cells in thrombin induced nerve injury through LXRα signaling in mice." in: Neuroscience letters, Vol. 729, pp. 135007, (2020) (PubMed).

Gajendran, Parthasarathy, Tadepalli: "Comparative evaluation of cathepsin K levels in gingival crevicular fluid among smoking and nonsmoking patients with chronic periodontitis." in: Indian journal of dental research : official publication of Indian Society for Dental Research, Vol. 29, Issue 5, pp. 588-593, (2019) (PubMed).

Sahana, Rekha: "A bioactive exopolysaccharide from marine bacteria Alteromonas sp. PRIM-28 and its role in cell proliferation and wound healing in vitro." in: International journal of biological macromolecules, Vol. 131, pp. 10-18, (2019) (PubMed).

Doss, Samarpita, Ganesan, Rasool: "Ferulic acid, a dietary polyphenol suppresses osteoclast differentiation and bone erosion via the inhibition of RANKL dependent NF-κB signalling pathway." in: Life sciences, Vol. 207, pp. 284-295, (2018) (PubMed).

Song, Jing, Hu, Yu, Cui et al.: "α-Linolenic Acid Inhibits Receptor Activator of NF-κB Ligand Induced (RANKL-Induced) Osteoclastogenesis and Prevents Inflammatory Bone Loss via Downregulation of Nuclear Factor-KappaB-Inducible ..." in: Medical science monitor : international medical journal of experimental and clinical research, Vol. 23, pp. 5056-5069, (2018) (PubMed).

Xu, Zhang, Wang, Li, Tan, Liang, Shen, Cai, Jin, Li, Xiao, Xu, Jiang, Bai: "TSC1 regulates osteoclast podosome organization and bone resorption through mTORC1 and Rac1/Cdc42." in: Cell death and differentiation, Vol. 25, Issue 9, pp. 1549-1566, (2018) (PubMed).

Pagani, Torricelli, Veronesi, Salamanna, Cepollaro, Fini: "An advanced tri-culture model to evaluate the dynamic interplay among osteoblasts, osteoclasts, and endothelial cells." in: Journal of cellular physiology, (2017) (PubMed).

Cubillos, Krieg, Norgauer: "Effect of Vitamin D on Peripheral Blood Mononuclear Cells from Patients with Psoriasis Vulgaris and Psoriatic Arthritis." in: PLoS ONE, Vol. 11, Issue 4, pp. e0153094, (2016) (PubMed).

Kubler, Larsson, Luna, Andrade, Amaral, Urbanowski, Orandle, Bock, Ammerman, Cheung, Winglee, Halushka, Park, Sher, Friedland, Elkington, Bishai: "Cathepsin K Contributes to Cavitation and Collagen Turnover in Pulmonary Tuberculosis." in: The Journal of infectious diseases, Vol. 213, Issue 4, pp. 618-27, (2016) (PubMed).

Forte, Torricelli, Boanini, Gazzano, Rubini, Fini, Bigi: "Antioxidant and bone repair properties of quercetin-functionalized hydroxyapatite: An in vitro osteoblast-osteoclast-endothelial cell co-culture study." in: Acta biomaterialia, Vol. 32, pp. 298-308, (2016) (PubMed).

Synonyms and alternative names related to Cathepsin K

cathepsin K (CTSK), cathepsin K (Ctsk), cathepsin K (ctsk), cathepsin K L homeolog (ctsk.L), Cathepsin K (catk), cathepsin K (catk), AI323530, catK, catk, CTS02, cts02, CTSK, CTSO, ctso, CTSO1, ctso1, CTSO2, ctso2, MMS10-Q, Ms10q, OC-2, PKND, pknd, PYCD, pycd, wu:fa95f03, wu:fb08b05, zgc:110367

Protein level used designations for Cathepsin K

  • cathepsin O
  • cathepsin O1
  • cathepsin O2
  • cathepsin X
  • Cat K
  • minisatellite 10q detected by probe MMS10
  • JTAP-1
  • cathepsin K
  • cathepsin K preproprotein
  • etID33526.16
  • cathepsin K (pycnodysostosis)
  • protein OC-2
  • Cathepsin K
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