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Cathepsin F Products

(Cathepsin F (CTSF))

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Cathepsins are papain family cysteine proteinases that represent a major component of the lysosomal proteolytic system. Cathepsins generally contain a signal sequence, followed by a propeptide and then a catalytically active mature region. The very long (251 amino acid residues) proregion of the cathepsin F precursor contains a C-terminal domain similar to the pro-segment of cathepsin L-like enzymes, a 50-residue flexible linker peptide, and an N-terminal domain predicted to adopt a cystatin-like fold. The cathepsin F proregion is unique within the papain family cysteine proteases in that it contains this additional N-terminal segment predicted to share structural similarities with cysteine protease inhibitors of the cystatin superfamily. This cystatin-like domain contains some of the elements known to be important for inhibitory activity. CTSF encodes a predicted protein of 484 amino acids which contains a 19 residue signal peptide. Cathepsin F contains five potential N-glycosylation sites, and it may be targeted to the endosomal/lysosomal compartment via the mannose 6-phosphate receptor pathway. The cathepsin F gene is ubiquitously expressed, and it maps to chromosome 11q13, close to the gene encoding cathepsin W. [provided by RefSeq, Jul 2008].

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Featured Cathepsin F Categories

Cathepsin F Antibodies

High quality antibodies with extensive validation data.

Cathepsin F ELISA Kits

Reliable ELISA kits for a wide range of species.

Cathepsin F Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Cathepsin F Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Application WB, IHC, ICC, IP
Validations
  • (3)
Cat. No. ABIN7444898
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, FACS, IHC (p)
Validations
  • (3)
Cat. No. ABIN390488
Quantity 400 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IF
Validations
  • (2)
Cat. No. ABIN6139225
Quantity 100 μL
Datasheet Datasheet

Recommended Cathepsin F ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6965510
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN5690840
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
Cat. No. ABIN6203072
Quantity 96 tests
Datasheet Datasheet

Recommended Cathepsin F Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7122180
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1350712
Quantity 10 μg
Datasheet Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7419268
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our Cathepsin F products

Maubach, Lim, Zhuo: "Nuclear cathepsin F regulates activation markers in rat hepatic stellate cells." in: Molecular biology of the cell, Vol. 19, Issue 10, pp. 4238-48, (2008) (PubMed).

da Silva Ferreira, Savoldi, Sueli Bonato, Goldman, Goldman: "Fungal metabolic model for tyrosinemia type 3: molecular characterization of a gene encoding a 4-hydroxy-phenyl pyruvate dioxygenase from Aspergillus nidulans." in: Eukaryotic cell, Vol. 5, Issue 8, pp. 1441-5, (2006) (PubMed).

Dorn, Zhao, Granberg, Hösel, Webb, Svensson, Pettersson, Doerfler: "Identification of specific cellular genes up-regulated late in adenovirus type 12 infection." in: Journal of virology, Vol. 79, Issue 4, pp. 2404-12, (2005) (PubMed).

Synonyms and alternative names related to Cathepsin F

cathepsin F (CTSF), cathepsin F (ctsf), cathepsin F (Ctsf), cathepsin W (ctsw), cathepsin F (Tsp_02382), ACYPI000376, AI481912, catf, CATSF, cb420, CLN13, CTSF, Ctsf, LOC100101596, MGC140519, sb:cb420, zgc:153093

Protein level used designations for Cathepsin F

  • cathepsin F
  • hypothetical protein LOC100158959
  • Cathepsin F
  • cathepsin F-like
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