Cathepsin D Products
(Cathepsin D (CTSD))
Categories
This gene encodes a lysosomal aspartyl protease composed of a dimer of disulfide-linked heavy and light chains, both produced from a single protein precursor. This proteinase, which is a member of the peptidase C1 family, has a specificity similar to but narrower than that of pepsin A. Transcription of this gene is initiated from several sites, including one which is a start site for an estrogen-regulated transcript. Mutations in this gene are involved in the pathogenesis of several diseases, including breast cancer and possibly Alzheimer disease. [provided by RefSeq, Jul 2008].
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Featured Cathepsin D Categories
Cathepsin D Antibodies
High quality antibodies with extensive validation data.
Cathepsin D ELISA Kits
Reliable ELISA kits for a wide range of species.
Cathepsin D Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Cathepsin D Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Avian, Cat, Chicken, Cow, Dog, Donkey, Goat, Guinea Pig, Hamster, Horse, Human, Monkey, Mouse, Pig, Rabbit, Rat, Sheep
Application
WB, IHC (p), IF, IHC (fro), IEM
Validations
- (1)
- (12)
Cat. No.
ABIN6254162
Quantity
600 μg
Datasheet
Datasheet
Reactivity
Mouse
Application
WB, IHC, IP, ICC
Validations
- (6)
Cat. No.
ABIN7433375
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IP
Validations
- (6)
Cat. No.
ABIN514771
Quantity
100 μL
Datasheet
Datasheet
Recommended Cathepsin D ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (3)
- (5)
Cat. No.
ABIN6574268
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (5)
Cat. No.
ABIN6574269
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6962085
Quantity
96 tests
Datasheet
Datasheet
Recommended Cathepsin D Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1350708
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Human Cells
Validations
- (1)
Cat. No.
ABIN7320739
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
- (3)
- (1)
Cat. No.
ABIN1095534
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our Cathepsin D products
: "Plasma cathepsin D activity is negatively associated with hepatic insulin sensitivity in overweight and obese humans." in: Diabetologia, Vol. 63, Issue 2, pp. 374-384, (2020) (PubMed).: "SPRED2 deficiency elicits cardiac arrhythmias and premature death via impaired autophagy." in: Journal of molecular and cellular cardiology, Vol. 129, pp. 13-26, (2019) (PubMed).
: "Elevated Peripheral Myelin Protein 22, Reduced Mitotic Potential, and Proteasome Impairment in Dermal Fibroblasts from Charcot-Marie-Tooth Disease Type 1A Patients." in: The American journal of pathology, Vol. 188, Issue 3, pp. 728-738, (2019) (PubMed).
: "Natural history of Helicobacter pylori VacA toxin in human gastric epithelium in vivo: vacuoles and beyond." in: Scientific reports, Vol. 7, Issue 1, pp. 14526, (2018) (PubMed).
: "Naturally Occurring Variants in LRP1 (Low-Density Lipoprotein Receptor-Related Protein 1) Affect HDL (High-Density Lipoprotein) Metabolism Through ABCA1 (ATP-Binding Cassette A1) and SR-B1 (Scavenger ..." in: Arteriosclerosis, thrombosis, and vascular biology, Vol. 38, Issue 7, pp. 1440-1453, (2018) (PubMed).
: "A C-terminally truncated mouse Best3 splice variant targets and alters the ion balance in lysosome-endosome hybrids and the endoplasmic reticulum." in: Scientific reports, Vol. 6, pp. 27332, (2018) (PubMed).
: "Increased Cathepsin D Correlates with Clinical Parameters in Newly Diagnosed Type 2 Diabetes." in: Disease markers, Vol. 2017, pp. 5286408, (2018) (PubMed).
: "Endogenous Murine Amyloid-β Peptide Assembles into Aggregates in the Aged C57BL/6J Mouse Suggesting These Animals as a Model to Study Pathogenesis of Amyloid-β Plaque Formation." in: Journal of Alzheimer's disease : JAD, Vol. 61, Issue 4, pp. 1425-1450, (2017) (PubMed).
: "Berberine ameliorates intrahippocampal kainate-induced status epilepticus and consequent epileptogenic process in the rat: Underlying mechanisms." in: Biomedicine & pharmacotherapy, Vol. 87, pp. 200-208, (2017) (PubMed).
: "Inhibition of autophagosome-lysosome fusion by ginsenoside Ro via the ESR2-NCF1-ROS pathway sensitizes esophageal cancer cells to 5-fluorouracil-induced cell death via the CHEK1-mediated DNA damage ..." in: Autophagy, Vol. 12, Issue 9, pp. 1593-613, (2017) (PubMed).
Synonyms and alternative names related to Cathepsin D
cathepsin D (ctsd), cathepsin D (LOC398557), cathepsin D S homeolog (ctsd.S), cathepsin D (CatD), lysosomal aspartic protease (LOC5567565), cathepsin D (LOC100136761), cathepsin D (CTSD), cathepsin D (Cathd), cathepsin D (ctsD), cathepsin D (catd), cathepsin D (Ctsd), cathepsin D-like (LOC443060), catD, CatD, Cathd, CD, CLN10, CPSD, CTSD, DDBDRAFT_0205785, DDBDRAFT_0215012, DDB_0205785, DDB_0215012, DKFZp469J0315, fb93e11, fj17b09, LOC398557, LOC100136761, wu:fb93e11, wu:fj17b09Protein level used designations for Cathepsin D
- etID16901.18
- cathepsin D
- aspartic protease
- cathepsin d
- preprocathepsin D
- ceroid-lipofuscinosis, neuronal 10
- lysosomal aspartyl peptidase
- lysosomal aspartyl protease
- cathepsin D (lysosomal aspartyl peptidase)
- cathepsin D (lysosomal aspartyl protease)
- prepro-cathepsin D, prepro-CD
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