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Caspase 3 Products

(Caspase 3 (CASP3))

Categories

This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 6, 7 and 9, and the protein itself is processed by caspases 8, 9 and 10. It is the predominant caspase involved in the cleavage of amyloid-beta 4A precursor protein, which is associated with neuronal death in Alzheimer's disease. Alternative splicing of this gene results in two transcript variants that encode the same protein. [provided by RefSeq, Jul 2008].

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Featured Caspase 3 Categories

Caspase 3 Antibodies

High quality antibodies with extensive validation data.

Caspase 3 ELISA Kits

Reliable ELISA kits for a wide range of species.

Caspase 3 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Caspase 3 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Cow, Goat, Human, Mouse, Rat
Application WB, IF (cc)
Validations
  • (86)
  • (7)
Cat. No. ABIN724625
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC (p)
Validations
  • (103)
  • (5)
Cat. No. ABIN3043802
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p), ICC
Validations
  • (94)
  • (5)
Cat. No. ABIN3044357
Quantity 100 μg
Datasheet Datasheet

Recommended Caspase 3 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (9)
  • (6)
Cat. No. ABIN6574178
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (29)
  • (1)
Cat. No. ABIN6954418
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6965466
Quantity 96 tests
Datasheet Datasheet

Recommended Caspase 3 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7122165
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1348103
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1348105
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our Caspase 3 products

Ding, Loganathan, Zhou, Sayour, Brlecic, Radovits, Domain, Korkmaz, Karck, Szabó, Korkmaz-Icöz: "Alpha-1-Antitrypsin Protects Vascular Grafts of Brain-Dead Rats Against Ischemia/Reperfusion Injury." in: The Journal of surgical research, Vol. 283, pp. 953-964, (2023) (PubMed).

Yang, Jia, Xiao, Zhao, Lu, Chu, Shao, Pei, Zhang, Chen: "Baicalin Rescues Cognitive Dysfunction, Mitigates Neurodegeneration, and Exerts Anti-Epileptic Effects Through Activating TLR4/MYD88/Caspase-3 Pathway in Rats." in: Drug design, development and therapy, Vol. 15, pp. 3163-3180, (2022) (PubMed).

Dong, Yang, Zhao, Guo: "Anisodamine hydrobromide ameliorates cardiac damage after resuscitation." in: Experimental and therapeutic medicine, Vol. 23, Issue 6, pp. 422, (2022) (PubMed).

Korkmaz-Icöz, Sistori, Loganathan, Sayour, Brlecic, Radovits, Brune, Karck, Szabó: "Bone Marrow Culture-Derived Conditioned Medium Recovers Endothelial Function of Vascular Grafts following In Vitro Ischemia/Reperfusion Injury in Diabetic Rats." in: Stem cells international, Vol. 2022, pp. 7019088, (2022) (PubMed).

Kovacs, Maresca, Flori, Mastrofrancesco, Picardo, Cardinali: "Bovine colostrum induces the differentiation of human primary keratinocytes." in: FASEB journal : official publication of the Federation of American Societies for Experimental Biology, Vol. 34, Issue 5, pp. 6302-6321, (2021) (PubMed).

Kurakula, Naveen: "In Situ Gel Loaded with Chitosan-Coated Simvastatin Nanoparticles: Promising Delivery for Effective Anti-Proliferative Activity against Tongue Carcinoma." in: Marine drugs, Vol. 18, Issue 4, (2021) (PubMed).

Al Zaabi, Al Salam, Al Suleimani, Ashique, Manoj, Nemmar, Ali: "Effects of repeated increasing doses of cisplatin as models of acute kidney injury and chronic kidney disease in rats." in: Naunyn-Schmiedeberg's archives of pharmacology, Vol. 394, Issue 2, pp. 249-259, (2021) (PubMed).

Caputo, Piccialli, Ciccone, de Caprariis, Massa, De Feo, Pannaccione: "Lavender and coriander essential oils and their main component linalool exert a protective effect against amyloid-β neurotoxicity." in: Phytotherapy research : PTR, Vol. 35, Issue 1, pp. 486-493, (2021) (PubMed).

Adedara, Fabunmi, Ayenitaju, Atanda, Adebowale, Ajayi, Owoeye, Rocha, Farombi: "Neuroprotective mechanisms of selenium against arsenic-induced behavioral impairments in rats." in: Neurotoxicology, Vol. 76, pp. 99-110, (2021) (PubMed).

Owumi, Adedara, Farombi, Oyelere: "Protocatechuic acid modulates reproductive dysfunction linked to furan exposure in rats." in: Toxicology, Vol. 442, pp. 152556, (2021) (PubMed).

Synonyms and alternative names related to Caspase 3

caspase 3 (CASP3), caspase 3 (Casp3), caspase 3 S homeolog (casp3.S), caspase 3, apoptosis-related cysteine peptidase a (casp3a), caspase 3, apoptosis-related cysteine peptidase (Casp3), A830040C14Rik, AC-3, Apopain, CASP-3, casp3, Caspase-3, caspase-3, CC3, CPP32, CPP32B, Lice, mldy, SCA-1, xcpp32, Yama, zgc:100890

Protein level used designations for Caspase 3

  • CASP-3
  • CPP-32
  • PARP cleavage protease
  • SREBP cleavage activity 1
  • apopain
  • caspase 3, apoptosis-related cysteine protease
  • caspase-3
  • cysteine protease CPP32
  • procaspase3
  • protein Yama
  • SCA-1
  • caspase 3, apoptosis related cysteine protease
  • CPP32beta
  • Caspase 3 apoptosis related cysteine protease (ICE-like cysteine protease)
  • Caspase 3, apoptosis related cysteine protease (ICE-like cysteine protease)
  • IRP
  • yama protein
  • Caspase-3-like protein
  • caspase 3, apoptosis-related cysteine peptidase a
  • caspase 3, apoptosis-related cysteine protease a
  • caspase 3, apoptosis-related cysteine peptidase
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