Caspase 2 Products
(Caspase 2, Apoptosis-Related Cysteine Peptidase (CASP2))
Categories
This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Caspases mediate cellular apoptosis through the proteolytic cleavage of specific protein substrates. The encoded protein may function in stress-induced cell death pathways, cell cycle maintenance, and the suppression of tumorigenesis. Increased expression of this gene may play a role in neurodegenerative disorders including Alzheimer's disease, Huntington's disease and temporal lobe epilepsy. Alternatively spliced transcript variants encoding multiple isoforms have been observed for this gene. [provided by RefSeq, Jan 2011].
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Featured Caspase 2 Categories
Caspase 2 Antibodies
High quality antibodies with extensive validation data.
Caspase 2 ELISA Kits
Reliable ELISA kits for a wide range of species.
Caspase 2 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Caspase 2 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (5)
Cat. No.
ABIN7431443
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC
Validations
- (4)
Cat. No.
ABIN7261672
Quantity
200 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (4)
Cat. No.
ABIN6137960
Quantity
100 μL
Datasheet
Datasheet
Recommended Caspase 2 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6965459
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6965458
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Qualitative Cell ELISA
Validations
Cat. No.
ABIN1380981
Quantity
96 tests
Datasheet
Datasheet
Recommended Caspase 2 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1348098
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1348097
Quantity
25 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7419970
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our Caspase 2 products
: "Aflatoxin B1 affects apoptosis and expression of Bax, Bcl-2, and Caspase-3 in thymus and bursa of fabricius in broiler chickens." in: Environmental toxicology, (2015) (PubMed).: "Protective Effects of Baicalin on A?????-Induced Learning and Memory Deficit, Oxidative Stress, and Apoptosis in Rat." in: Cellular and molecular neurobiology, Vol. 35, Issue 5, pp. 623-32, (2015) (PubMed).
: "Inhibitory activity of apogossypol in human prostate cancer in vitro and in vivo." in: Molecular medicine reports, Vol. 11, Issue 6, pp. 4142-8, (2015) (PubMed).
: "Radioprotective activity of neutral polysaccharides isolated from the fruiting bodies of Hohenbuehelia serotina." in: Physica medica : PM : an international journal devoted to the applications of physics to medicine and biology : official journal of the Italian Association of Biomedical Physics (AIFB), Vol. 31, Issue 4, pp. 352-9, (2015) (PubMed).
: "Inhibitory effect of tetramethylpyrazine preconditioning on overload training-induced myocardial apoptosis in rats." in: Chinese journal of integrative medicine, Vol. 21, Issue 6, pp. 423-30, (2015) (PubMed).
: "Apoptosis-related protein expression in rabbits with blast brain injury following early hyperbaric oxygen therapy." in: Neural regeneration research, Vol. 7, Issue 17, pp. 1318-24, (2015) (PubMed).
: "Forsythiaside protects against hydrogen peroxide-induced oxidative stress and apoptosis in PC12 cell." in: Neurochemical research, Vol. 40, Issue 1, pp. 27-35, (2015) (PubMed).
: "Effects of PDTC on NF-?B expression and apoptosis in rats with severe acute pancreatitis-associated lung injury." in: International journal of clinical and experimental medicine, Vol. 8, Issue 3, pp. 3258-70, (2015) (PubMed).
: "Transcriptional and posttranslational regulation of insulin-like growth factor binding protein-3 by Akt3." in: Carcinogenesis, Vol. 35, Issue 10, pp. 2232-43, (2014) (PubMed).
: "Apoptotic induction of lung adenocarcinoma A549 cells infected by recombinant RVG Newcastle disease virus (rL-RVG) in vitro." in: Molecular medicine reports, Vol. 11, Issue 1, pp. 317-26, (2014) (PubMed).
Synonyms and alternative names related to Caspase 2
caspase 2 (CASP2), caspase 2 L homeolog (casp2.L), caspase-2 (CpipJ_CPIJ008254), caspase 2 (Casp2), CASP-2, Caspase-2, ICH-1, ICH-1L/1S, ICH1, ICH1L1S, NEDD-2, Nedd2, NEDD2, PPP1R57, xCaspase-2Protein level used designations for Caspase 2
- caspase-2
- CASP-2
- ICH-1 protease
- protease ICH-1
- NEDD-2
- neural precursor cell expressed developmentally down-regulated protein 2
- protein phosphatase 1, regulatory subunit 57
- caspase 2, apoptosis-related cysteine peptidase (neural precursor cell expressed, developmentally down-regulated 2)
- ICH1 protease
- caspase 2, apoptosis-related cysteine protease
- cysteine protease caspase-2
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