Caspase 10 Products
(Caspase 10, Apoptosis-Related Cysteine Peptidase (CASP10))
Categories
This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This protein cleaves and activates caspases 3 and 7, and the protein itself is processed by caspase 8. Mutations in this gene are associated with type IIA autoimmune lymphoproliferative syndrome, non-Hodgkin lymphoma and gastric cancer. Alternatively spliced transcript variants encoding different isoforms have been described for this gene. [provided by RefSeq, Apr 2011].
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Featured Caspase 10 Categories
Caspase 10 Antibodies
High quality antibodies with extensive validation data.
Caspase 10 ELISA Kits
Reliable ELISA kits for a wide range of species.
Caspase 10 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Caspase 10 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, ICC, IP
Validations
- (9)
Cat. No.
ABIN7443104
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human, Mouse
Application
WB, ELISA, IHC, IF, ICC
Validations
- (5)
Cat. No.
ABIN6260480
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (4)
Cat. No.
ABIN514026
Quantity
100 μg
Datasheet
Datasheet
Recommended Caspase 10 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6965451
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN1113980
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Qualitative Cell ELISA
Validations
Cat. No.
ABIN1380980
Quantity
96 tests
Datasheet
Datasheet
Recommended Caspase 10 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1348091
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1348093
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1348090
Quantity
25 μg
Datasheet
Datasheet
Latest Publications for our Caspase 10 products
: "Protective role of sodium selenite on histopathological lesions, decreased T-cell subsets and increased apoptosis of thymus in broilers intoxicated with aflatoxin B?." in: Food and chemical toxicology : an international journal published for the British Industrial Biological Research Association, Vol. 59, pp. 446-54, (2013) (PubMed).: "Carnitine sensitizes TRAIL-resistant cancer cells to TRAIL-induced apoptotic cell death through the up-regulation of Bax." in: Biochemical and biophysical research communications, Vol. 428, Issue 1, pp. 185-90, (2012) (PubMed).
: "Early processing of Bid and caspase-6, -8, -10, -14 in the canine brain during cardiac arrest and resuscitation." in: Experimental neurology, Vol. 189, Issue 2, pp. 261-79, (2004) (PubMed).
: "Inactivating mutations of the caspase-10 gene in gastric cancer." in: Oncogene, Vol. 21, Issue 18, pp. 2919-25, (2002) (PubMed).
: "Molecular cloning and characterization of two novel pro-apoptotic isoforms of caspase-10." in: The Journal of biological chemistry, Vol. 274, Issue 15, pp. 10301-8, (1999) (PubMed).
: "Neurturin, a novel neurotrophic factor, is localized to mouse chromosome 17 and human chromosome 19p13.3." in: Genomics, Vol. 44, Issue 1, pp. 137-40, (1997) (PubMed).
: "Caspases: the executioners of apoptosis." in: The Biochemical journal, Vol. 326 ( Pt 1), Issue 5693, pp. 1-16, (1997) (PubMed).
: "In vitro activation of CPP32 and Mch3 by Mch4, a novel human apoptotic cysteine protease containing two FADD-like domains." in: Proceedings of the National Academy of Sciences of the United States of America, Vol. 93, Issue 15, pp. 7464-9, (1996) (PubMed).
Synonyms and alternative names related to Caspase 10
caspase 10 S homeolog (casp10.S), caspase 10 (casp10), caspase 10 (CASP10), caspase 10 (Casp10), caspase-10 (LOC100848685), alps2, ALPS2, caspace-10, caspase-10, flice2, FLICE2, mch4, MCH4, xCaspace-10, xCaspase-10Protein level used designations for Caspase 10
- caspase-10
- caspase 10, apoptosis-related cysteine protease
- CASP-10
- FADD-like ICE2
- FAS-associated death domain protein interleukin-1B-converting enzyme 2
- ICE-like apoptotic protease 4
- apoptotic protease MCH-4
- interleukin-1B-converting enzyme 2
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