Phone:
+1 877 302 8632
Fax:
+1 888 205 9894 (Toll-free)
E-Mail:
orders@antibodies-online.com

Caspase 1 Products

(Caspase 1 (CASP1))

Categories

This gene encodes a protein which is a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce 2 subunits, large and small, that dimerize to form the active enzyme. This gene was identified by its ability to proteolytically cleave and activate the inactive precursor of interleukin-1, a cytokine involved in the processes such as inflammation, septic shock, and wound healing. This gene has been shown to induce cell apoptosis and may function in various developmental stages. Studies of a similar gene in mouse suggest a role in the pathogenesis of Huntington disease. Alternative splicing results in transcript variants encoding distinct isoforms. [provided by RefSeq, Mar 2012].

antibodies-online.com stands for high-quality research products. Search, find and order tools with extensive validation data, images, references. Our scientific customer service is always at your disposal if you have any questions about the selection or application of our products.

Featured Caspase 1 Categories

Caspase 1 Antibodies

High quality antibodies with extensive validation data.

Caspase 1 ELISA Kits

Reliable ELISA kits for a wide range of species.

Caspase 1 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Caspase 1 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (7)
Cat. No. ABIN7438055
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (7)
Cat. No. ABIN7433831
Quantity 100 μL
Datasheet Datasheet
Reactivity Mouse
Application WB, IHC, IP, ICC
Validations
  • (8)
Cat. No. ABIN7437506
Quantity 100 μL
Datasheet Datasheet

Recommended Caspase 1 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (3)
  • (5)
Cat. No. ABIN6574284
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6954410
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6965449
Quantity 96 tests
Datasheet Datasheet

Recommended Caspase 1 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7122160
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7122161
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1776262
Quantity 10 μg
Datasheet Datasheet

Latest Publications for our Caspase 1 products

Lv, Liu, Ye, Yang, Duan, Yao, Li, Tang, Chen, Liu, Deng, Wang, Xing, Liang, Xu, Ye: "XIST Inhibition Attenuates Calcium Oxalate Nephrocalcinosis-Induced Renal Inflammation and Oxidative Injury via the miR-223/NLRP3 Pathway." in: Oxidative medicine and cellular longevity, Vol. 2021, pp. 1676152, (2022) (PubMed).

Wu, He, Li, Xu, Zhong, Bu, Huang: "Efficient and Consistent Orthotopic Osteosarcoma Model by Cell Sheet Transplantation in the Nude Mice for Drug Testing." in: Frontiers in bioengineering and biotechnology, Vol. 9, pp. 690409, (2021) (PubMed).

Zhou, Xiao, Zhao, Tan, Long, Yu, He: "Enhanced Autolysosomal Function Ameliorates the Inflammatory Response Mediated by the NLRP3 Inflammasome in Alzheimer's Disease." in: Frontiers in aging neuroscience, Vol. 13, pp. 629891, (2021) (PubMed).

Wang, Li, Peng, Hu, Rao, Li: "HMGB1 participates in LPS‑induced acute lung injury by activating the AIM2 inflammasome in macrophages and inducing polarization of M1 macrophages via TLR2, TLR4, and RAGE/NF‑κB signaling pathways." in: International journal of molecular medicine, Vol. 45, Issue 1, pp. 61-80, (2020) (PubMed).

Cabus, Kabukcu, Fenkci, Caner, Oztekin, Fenkci, Enli: "Serum Caspase-1 levels in women with polycystic ovary syndrome." in: Taiwanese journal of obstetrics & gynecology, Vol. 59, Issue 2, pp. 207-210, (2020) (PubMed).

Lopes de Oliveira, Alarcón de la Lastra, Rosillo, Castejon Martinez, Sánchez-Hidalgo, Rolim Medeiros, Villegas: "Preventive effect of bergenin against the development of TNBS-induced acute colitis in rats is associated with inflammatory mediators inhibition and NLRP3/ASC inflammasome signaling pathways." in: Chemico-biological interactions, Vol. 297, pp. 25-33, (2019) (PubMed).

Mandal, Feng, Lyons, Berger, Otani, DeLaney, Tharp, Maner-Smith, Burd, Schaeffer, Hoffman, Capriotti, Roback, Young, Liang, Ortlund, DiPaolo, Bosinger, Bertin, Gough, Brodsky, Coopersmith et al.: "Caspase-8 Collaborates with Caspase-11 to Drive Tissue Damage and Execution of Endotoxic Shock. ..." in: Immunity, Vol. 49, Issue 1, pp. 42-55.e6, (2019) (PubMed).

Liu, Mateer, Hsu, Goggins, Tay, Mathe, Fan, Neal, Bruce, Burns, Minahan, Maltby, Fricker, Foster, Wark, Hansbro, Keely: "Platelet activating factor receptor regulates colitis-induced pulmonary inflammation through the NLRP3 inflammasome." in: Mucosal immunology, Vol. 12, Issue 4, pp. 862-873, (2019) (PubMed).

Raval, Schatz, Bhattacharya, dAdesky, Rundek, Dietrich, Bramlett: "Whole Body Vibration Therapy after Ischemia Reduces Brain Damage in Reproductively Senescent Female Rats." in: International journal of molecular sciences, Vol. 19, Issue 9, (2019) (PubMed).

Pronin, Pham, An, Dvoriantchikova, Reshetnikova, Qiao, Kozhekbaeva, Reiser, Slepak, Shestopalov: "Inflammasome Activation Induces Pyroptosis in the Retina Exposed to Ocular Hypertension Injury." in: Frontiers in molecular neuroscience, Vol. 12, pp. 36, (2019) (PubMed).

Synonyms and alternative names related to Caspase 1

caspase 1 (CASP1), caspase 1 (Casp1), caspase 1, apoptosis-related cysteine peptidase (CASP1), caspase 4, apoptosis-related cysteine peptidase (CASP4), Death caspase-1 (Dcp-1), caspase-1 (Caspase1), caspase (LOC5564196), caspase recruitment domain-containing protein 16 (LOC451519), caspase-1 (CASP1), caspase 4 (CASP4), CASP1, ccp1, CG5370, DCP-1, dcp-1, DCP1, Dcp1, dcp1, Dmel\\CG5370, ICE, Ice, IL1BC, Il1bc, l(2)01862, l(2)02132, P45

Protein level used designations for Caspase 1

  • CASP1 nirs variant 1
  • IL-1 beta-converting enzyme
  • IL1B-convertase
  • caspase 1, apoptosis-related cysteine peptidase (interleukin 1, beta, convertase)
  • caspase-1
  • interleukin 1, beta, convertase
  • interleukin 1-B converting enzyme
  • CASP-1
  • IL-1B converting enzyme
  • IL-1BC
  • interleukin 1 beta-converting enzyme
  • interleukin-1 beta convertase
  • interleukin-1 beta-converting enzyme
  • p45
  • Interleukin 1beta converting enzyme
  • caspase 1, apoptosis-related cysteine protease (interleukin 1, beta, convertase)
  • ICE
  • interleukin-1 beta converting enzyme
  • caspase-1/caspase-4 hybrid
  • CG5370-PA
  • Dcp-1-PA
  • caspase
  • caspase 1
  • death caspase-1
You are here:
Support