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CASP5 Proteins

(Caspase 5, Apoptosis-Related Cysteine Peptidase (CASP5))

This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. Overexpression of the active form of this enzyme induces apoptosis in fibroblasts. Max, a central component of the Myc\\/Max\\/Mad transcription regulation network important for cell growth, differentiation, and apoptosis, is cleaved by this protein\\\\; this process requires Fas-mediated dephosphorylation of Max. The expression of this gene is regulated by interferon-gamma and lipopolysaccharide. Alternatively spliced transcript variants have been identified for this gene. [provided by RefSeq, Aug 2010].

recommended

CASP5 Protein (AA 309-418) (GST tag) (ABIN1348109)

CASP5 Origin: Human Host: Wheat germ Recombinant WB, AA, AP, ELISA

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recommended

CASP5 Protein (AA 145-327) (His tag) (ABIN7391987)

CASP5 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 97 % SDS, WB, Imm, PC

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recommended

CASP5 Protein (AA 137-327, partial) (His-SUMO Tag) (ABIN5709203)

CASP5 Origin: Human Host: Escherichia coli (E. coli) Recombinant > 90 % SDS

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CASP5 Proteins by Origin

Find CASP5 Proteins for a variety of species such as anti-Human CASP5. The species listed below are among those available. Click on a link to go to the corresponding products.

CASP5 Proteins by Source

Here you will find CASP5 Proteins proteins organized by several key sources. By clicking on a link, you can access the products. For additional sources, please use our search function.

CASP5 Proteins by Protein Type

Here you can find CASP5 Proteins proteins categorized by available protein types. Additional protein types can be located using our search function.

CASP5 Proteins by Application

Find CASP5 Proteins validated for a specific application such as SDS, WB, AP, AA. Some of the available applications are listed below. Click on a link to go to the corresponding products.

Popular CASP5 Proteins

Product

Reactivity

Source

Validations

Cat. No.

Quantity

Datasheet

CASP5 Protein (AA 309-418) (GST tag)

Reactivity Human

Source Wheat germ

Validations

Cat. No. ABIN1348109

Quantity 10 μg

Datasheet Datasheet

CASP5 Protein (AA 145-327) (His tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN7391987

Quantity 100 μg

Datasheet Datasheet

CASP5 Protein (AA 137-327, partial) (His-SUMO Tag)

Reactivity Human

Source Escherichia coli (E. coli)

Validations

Cat. No. ABIN5709203

Quantity 100 μg

Datasheet Datasheet

CASP5 Protein (AA 137-327, partial) (His tag)

Reactivity Human

Source Yeast

Validations

Cat. No. ABIN5713310

Quantity 100 μg

Datasheet Datasheet

Latest Publications for our CASP5 Proteins

Murakami, Tolstykh, Bao, Niu, Steuer, Bao, Chang, Espiritu, Bansal, Lam, Otto, Sofia, Furman: "Mechanism of activation of PSI-7851 and its diastereoisomer PSI-7977." in: The Journal of biological chemistry, Vol. 285, Issue 45, pp. 34337-47, (2010) (PubMed).

Chen, Xia, Fang, Hawke, Lu: "Caspase-10-mediated heat shock protein 90 beta cleavage promotes UVB irradiation-induced cell apoptosis." in: Molecular and cellular biology, Vol. 29, Issue 13, pp. 3657-64, (2009) (PubMed).

Hasegawa, Yamada, Komiyama, Hayashi, Ishibashi, Sunazuka, Izuhara, Sugahara, Tsuruda, Masuda, Takasu, Tsukasaki, Tomonaga, Kamihira et al.: "A novel natural compound, a cycloanthranilylproline derivative (Fuligocandin B), sensitizes leukemia cells to apoptosis induced by tumor necrosis factor related apoptosis-inducing ligand (TRAIL) ..." in: Blood, Vol. 110, Issue 5, pp. 1664-74, (2007) (PubMed).

Aliases for CASP5 Proteins

caspase 5 (CASP5) Proteins
caspase-5 (LOC100437308) Proteins
CASP5 Proteins
ICE(rel)III Proteins
ICEREL-III Proteins
ICH-3 Proteins

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CASP5 Proteins by Origin

CASP5 Proteins by Source

CASP5 Proteins by Protein Type

CASP5 Proteins by Application

Popular CASP5 Proteins

Latest Publications for our CASP5 Proteins

Aliases for CASP5 Proteins

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