CASP14 Products
(Caspase 14, Apoptosis-Related Cysteine Peptidase (CASP14))
Categories
This gene encodes a member of the cysteine-aspartic acid protease (caspase) family. Sequential activation of caspases plays a central role in the execution-phase of cell apoptosis. Caspases exist as inactive proenzymes which undergo proteolytic processing at conserved aspartic residues to produce two subunits, large and small, that dimerize to form the active enzyme. This caspase has been shown to be processed and activated by caspase 8 and caspase 10 in vitro, and by anti-Fas agonist antibody or TNF-related apoptosis inducing ligand in vivo. The expression and processing of this caspase may be involved in keratinocyte terminal differentiation, which is important for the formation of the skin barrier. [provided by RefSeq, Jul 2008].
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Featured CASP14 Categories
CASP14 Antibodies
High quality antibodies with extensive validation data.
CASP14 ELISA Kits
Reliable ELISA kits for a wide range of species.
CASP14 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended CASP14 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, ELISA, IF
Validations
- (4)
Cat. No.
ABIN565119
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human, Mouse, Rat
Application
WB, IHC (p)
Validations
- (5)
Cat. No.
ABIN3030293
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB
Validations
- (1)
- (2)
Cat. No.
ABIN2856832
Quantity
100 μL
Datasheet
Datasheet
Recommended CASP14 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (2)
- (1)
Cat. No.
ABIN6954413
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6965457
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6965455
Quantity
96 tests
Datasheet
Datasheet
Recommended CASP14 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1348095
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN1692301
Quantity
50 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7318250
Quantity
50 μg
Datasheet
Datasheet
Latest Publications for our CASP14 products
: "Enhanced Induction of Apoptosis in HaCaT Cells by Luteolin Encapsulated in PEGylated Liposomes-Role of Caspase-3/Caspase-14." in: Applied biochemistry and biotechnology, Vol. 188, Issue 1, pp. 147-164, (2019) (PubMed).: "Foreskin-isolated keratinocytes provide successful extemporaneous autologous paediatric skin grafts." in: Journal of tissue engineering and regenerative medicine, Vol. 10, Issue 3, pp. 252-60, (2016) (PubMed).
: "Dual Inhibition of PI3K/Akt and mTOR by the Dietary Antioxidant, Delphinidin, Ameliorates Psoriatic Features In Vitro and in an Imiquimod-Induced Psoriasis-Like Disease in Mice." in: Antioxidants & redox signaling, (2016) (PubMed).
: "Inactivation of mitogen-activated protein kinase signaling pathway reduces caspase-14 expression in impaired keratinocytes." in: Iranian journal of basic medical sciences, Vol. 19, Issue 1, pp. 28-33, (2016) (PubMed).
: "Luteolin induces caspase-14-mediated terminal differentiation in human epidermal keratinocytes." in: In vitro cellular & developmental biology. Animal, Vol. 51, Issue 10, pp. 1072-6, (2015) (PubMed).
: "Study of proliferation and 3D epidermal reconstruction from foreskin, auricular and trunk keratinocytes in children." in: Burns : journal of the International Society for Burn Injuries, Vol. 41, Issue 2, pp. 352-8, (2015) (PubMed).
: "Pyrrolidone carboxylic acid levels or caspase-14 expression in the corneocytes of lesional skin correlates with clinical severity, skin barrier function and lesional inflammation in atopic dermatitis." in: Journal of dermatological science, Vol. 76, Issue 3, pp. 231-9, (2014) (PubMed).
: "Phospho-?Np63? regulates AQP3, ALOX12B, CASP14 and CLDN1 expression through transcription and microRNA modulation." in: FEBS letters, Vol. 587, Issue 21, pp. 3581-6, (2013) (PubMed).
: "Association of caspase-14 and filaggrin expression with keratinization of the oral mucosa and reconstruction culture rat models." in: Journal of periodontal research, (2013) (PubMed).
: "Exogenous expression of caspase-14 induces tumor suppression in human salivary cancer cells by inhibiting tumor vascularization." in: Anticancer research, Vol. 29, Issue 10, pp. 3811-8, (2009) (PubMed).
Synonyms and alternative names related to CASP14
caspase 14, apoptosis-related cysteine peptidase (CASP14), caspase 14 (Casp14), caspase 14 (CASP14), caspase-14-like (LOC485601), caspase-14 (LOC780455), CASP14, MICE, mini-ICEProtein level used designations for CASP14
- caspase 14
- CASP-14
- caspase-14
- apoptosis-related cysteine protease
- caspase 14, apoptosis-related cysteine protease
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