Carboxy Methyl Lysine Products
(Carboxy Methyl Lysine (CML))
Categories
A reciprocal translocation between chromosomes 22 and 9 produces the Philadelphia chromosome, which is often found in patients with chronic myelogenous leukemia. The chromosome 22 breakpoint for this translocation is located within the BCR gene. The translocation produces a fusion protein which is encoded by sequence from both BCR and ABL, the gene at the chromosome 9 breakpoint. Although the BCR-ABL fusion protein has been extensively studied, the function of the normal BCR gene product is not clear. The protein has serine/threonine kinase activity and is a GTPase-activating protein for p21rac. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Jul 2008].
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Featured Carboxy Methyl Lysine Categories
Carboxy Methyl Lysine Antibodies
High quality antibodies with extensive validation data.
Carboxy Methyl Lysine ELISA Kits
Reliable ELISA kits for a wide range of species.
Recommended Carboxy Methyl Lysine Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Application
WB, ICC, IHC, ELISA
Validations
Cat. No.
ABIN1839078
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Application
EIA, WB, IHC (fro), IF, IHC (p)
Validations
Cat. No.
ABIN1105660
Quantity
0.1 mg
Datasheet
Datasheet
Recommended Carboxy Methyl Lysine ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Various Species
Analytical Method
Quantitative Competition ELISA
Validations
- (12)
- (1)
Cat. No.
ABIN6954344
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
- (1)
Cat. No.
ABIN6975955
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Quantitative Competition ELISA
Validations
- (1)
Cat. No.
ABIN6965400
Quantity
96 tests
Datasheet
Datasheet
Latest Publications for our Carboxy Methyl Lysine products
: "Plasma heparanase is associated with blood glucose levels but not urinary microalbumin excretion in type 2 diabetic nephropathy at the early stage." in: Renal failure, Vol. 39, Issue 1, pp. 698-701, (2018) (PubMed).: "Antiglycation and antioxidant activities of mogroside extract from Siraitia grosvenorii (Swingle) fruits." in: Journal of food science and technology, Vol. 55, Issue 5, pp. 1880-1888, (2018) (PubMed).
: "Na(+)/K(+)-ATPase interaction with methylglyoxal as reactive metabolic side product." in: Free radical biology & medicine, Vol. 108, pp. 146-154, (2017) (PubMed).
: "Regulatory landscape of AGE-RAGE-oxidative stress axis and its modulation by PPARγ activation in high fructose diet-induced metabolic syndrome." in: Nutrition & metabolism, Vol. 14, pp. 5, (2017) (PubMed).
: "High intake of dietary advanced glycation end-products is associated with increased arterial stiffness and inflammation in subjects with type 2 diabetes." in: Nutrition, metabolism, and cardiovascular diseases : NMCD, Vol. 27, Issue 11, pp. 978-984, (2017) (PubMed).
: "Advanced Glycation End Products Evolution after Pancreas-Kidney Transplantation: Plasmatic and Cutaneous Assessments." in: Oxidative medicine and cellular longevity, Vol. 2016, pp. 2189582, (2016) (PubMed).
: "Advanced glycation end-products accelerate the cardiac aging process through the receptor for advanced glycation end-products/transforming growth factor-β-Smad signaling pathway in cardiac ..." in: Geriatrics & gerontology international, Vol. 16, Issue 4, pp. 522-7, (2016) (PubMed).
: "Growth arrest specific 2-like protein 1 expression is upregulated in podocytes through advanced glycation end-products." in: Nephrology, dialysis, transplantation : official publication of the European Dialysis and Transplant Association - European Renal Association, (2016) (PubMed).
: "Association of serum N(ε)-Carboxy methyl lysine with severity of diabetic retinopathy." in: Journal of diabetes and its complications, Vol. 30, Issue 3, pp. 511-7, (2016) (PubMed).
: "Increased levels of N(ε)- Carboxy methyl lysine (N(ε)-CML) are associated with topographic alterations in retinal pigment epithelium: A preliminary study." in: Journal of diabetes and its complications, Vol. 30, Issue 5, pp. 868-72, (2016) (PubMed).
Synonyms and alternative names related to Carboxy Methyl Lysine
BCR, RhoGEF and GTPase activating protein (BCR), ALL, BCR1, CML, D22S11, D22S662, PHLProtein level used designations for Carboxy Methyl Lysine
- BCR/FGFR1 chimera protein
- FGFR1/BCR chimera protein
- breakpoint cluster region protein
- renal carcinoma antigen NY-REN-26
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