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Calpastatin Products

(Calpastatin (CAST))

Categories

The protein encoded by this gene is an endogenous calpain (calcium-dependent cysteine protease) inhibitor. It consists of an N-terminal domain L and four repetitive calpain-inhibition domains (domains 1-4), and it is involved in the proteolysis of amyloid precursor protein. The calpain/calpastatin system is involved in numerous membrane fusion events, such as neural vesicle exocytosis and platelet and red-cell aggregation. The encoded protein is also thought to affect the expression levels of genes encoding structural or regulatory proteins. Alternatively spliced transcript variants encoding different isoforms have been described. [provided by RefSeq, Jun 2010].

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Featured Calpastatin Categories

Calpastatin Antibodies

High quality antibodies with extensive validation data.

Calpastatin ELISA Kits

Reliable ELISA kits for a wide range of species.

Calpastatin Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Calpastatin Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application ELISA, IHC, Coat, StM
Validations
  • (6)
Cat. No. ABIN6940960
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC
Validations
  • (5)
Cat. No. ABIN5663576
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, ELISA, IHC, IF
Validations
  • (4)
Cat. No. ABIN7146551
Quantity 100 μg
Datasheet Datasheet

Recommended Calpastatin ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6965351
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6954306
Quantity 96 tests
Datasheet Datasheet
Reactivity Mouse
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6954307
Quantity 96 tests
Datasheet Datasheet

Recommended Calpastatin Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1348135
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1348133
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN935258
Quantity 1 mg
Datasheet Datasheet

Latest Publications for our Calpastatin products

Wan, Wang, Xiong, Xiang, Li, Wang, Liu, Niu, Peng, Jiang, Chai: "Elucidating a molecular mechanism that the deterioration of porcine meat quality responds to increased cortisol based on transcriptome sequencing." in: Scientific reports, Vol. 6, pp. 36589, (2018) (PubMed).

Huang, Rose, Hoffmann, Hashimoto, Bertino, Denk, Takano, Iwata, Saido, Hoffmann: "Calpastatin prevents NF-?B-mediated hyperactivation of macrophages and attenuates colitis." in: Journal of immunology (Baltimore, Md. : 1950), Vol. 191, Issue 7, pp. 3778-88, (2013) (PubMed).

Zór, Castellarnau, Pascual, Pich, Plasencia, Bardsley, Nistor: "Design, development and application of a bioelectrochemical detection system for meat tenderness prediction." in: Biosensors & bioelectronics, Vol. 26, Issue 11, pp. 4283-8, (2011) (PubMed).

Kaur, Mencl, Sahaboglu, Farinelli, van Veen, Zrenner, Ekström, Paquet-Durand, Arango-Gonzalez: "Calpain and PARP activation during photoreceptor cell death in P23H and S334ter rhodopsin mutant rats." in: PLoS ONE, Vol. 6, Issue 7, pp. e22181, (2011) (PubMed).

Zór, Ortiz, Saatci, Bardsley, Parr, Csöregi, Nistor: "Label free capacitive immunosensor for detecting calpastatin--a meat tenderness biomarker." in: Bioelectrochemistry (Amsterdam, Netherlands), Vol. 76, Issue 1-2, pp. 93-9, (2009) (PubMed).

Synonyms and alternative names related to Calpastatin

calpastatin (CAST), calpastatin (Cast), calpastatin S homeolog (cast.S), calpastatin (cast), calpastatin (VDBG_09182), Calpastatin (ical), BS-17, calp3, CAST, cast, DKFZp469E0716, sb:cb966, zgc:194249

Protein level used designations for Calpastatin

  • calpain inhibitor
  • sperm BS-17 component
  • calpastatin type III
  • calpastatin isoform III
  • calpastatin type I
  • calpastatin type II
  • calpastatin
  • Calpastatin
  • calpastatin-like
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