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Calpain 2 Products

(Calpain 2 (CAPN2))
The calpains, calcium-activated neutral proteases, are nonlysosomal, intracellular cysteine proteases. The mammalian calpains include ubiquitous, stomach-specific, and muscle-specific proteins. The ubiquitous enzymes consist of heterodimers with distinct large, catalytic subunits associated with a common small, regulatory subunit. This gene encodes the large subunit of the ubiquitous enzyme, calpain 2. Multiple heterogeneous transcriptional start sites in the 5' UTR have been reported. Two transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Mar 2009].

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Featured Calpain 2 Categories

Calpain 2 Antibodies

High quality antibodies with extensive validation data.

Calpain 2 ELISA Kits

Reliable ELISA kits for a wide range of species.

Calpain 2 Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Calpain 2 Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Application WB, ELISA, IHC, IF, IP
Validations
  • (5)
Cat. No. ABIN7146540
Quantity 100 μg
Datasheet Datasheet
Reactivity Human
Application WB, IHC, IP, ICC
Validations
  • (3)
Cat. No. ABIN7440830
Quantity 100 μL
Datasheet Datasheet
Reactivity Human
Application WB, IHC (p), FACS
Validations
  • (3)
Cat. No. ABIN6244177
Quantity 400 μL
Datasheet Datasheet

Recommended Calpain 2 ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Rat
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
  • (1)
Cat. No. ABIN6954298
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6954297
Quantity 96 tests
Datasheet Datasheet
Reactivity Rat
Analytical Method Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN432747
Quantity 96 tests
Datasheet Datasheet

Recommended Calpain 2 Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1347988
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source HEK-293 Cells
Validations
  • (9)
  • (1)
Cat. No. ABIN2713061
Quantity 20 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7413112
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our Calpain 2 products

Li, Liu, Li, Hong, Min, Hu, Tang, Wang, Yang, Hong: "Electrical stimulation activates calpain 2 and subsequently upregulates collagens via the integrin β1/TGF-β1 signaling pathway." in: Cellular signalling, Vol. 59, pp. 141-151, (2019) (PubMed).

Wan, Wang, Xiong, Xiang, Li, Wang, Liu, Niu, Peng, Jiang, Chai: "Elucidating a molecular mechanism that the deterioration of porcine meat quality responds to increased cortisol based on transcriptome sequencing." in: Scientific reports, Vol. 6, pp. 36589, (2018) (PubMed).

Zuo, Hu, Liu, Chen, Tao, Chen, Li: "Calpeptin attenuates cigarette smoke-induced pulmonary inflammation via suppressing calpain/IκBα signaling in mice and BEAS-2B cells." in: Pathology, research and practice, Vol. 214, Issue 8, pp. 1199-1209, (2018) (PubMed).

Paul, Gangwar, Bhargava, Ahmad: "STAT3-RXR-Nrf2 activates systemic redox and energy homeostasis upon steep decline in pO2 gradient." in: Redox biology, Vol. 14, pp. 423-438, (2018) (PubMed).

Abdul Nasir, Agarwal, Sheikh Abdul Kadir, Vasudevan, Tripathy, Iezhitsa, Mohammad Daher, Ibrahim, Mohd Ismail: "Reduction of oxidative-nitrosative stress underlies anticataract effect of topically applied tocotrienol in streptozotocin-induced diabetic rats." in: PLoS ONE, Vol. 12, Issue 3, pp. e0174542, (2017) (PubMed).

Lamothe, Guo, Li, Yang, Zhang: "The Human Ether-a-go-go-related Gene (hERG) Potassium Channel Represents an Unusual Target for Protease-mediated Damage." in: The Journal of biological chemistry, Vol. 291, Issue 39, pp. 20387-401, (2016) (PubMed).

Zhao, Cui, Zhou, Li, Zhang, Sun, Han, Zou, Wang, Li, Wang: "Calpain-Calcineurin-Nuclear Factor Signaling and the Development of Atrial Fibrillation in Patients with Valvular Heart Disease and Diabetes." in: Journal of diabetes research, Vol. 2016, pp. 4639654, (2016) (PubMed).

Pan, Zhou, Mahsut, Rohm, Berejnaia, Price, Chen, Castro-Perez, Lassman, McLaren, Conway, Jensen, Thomas, Reyes-Soffer, Ginsberg, Gutstein, Cleary, Previs, Roddy: "Static and turnover kinetic measurement of protein biomarkers involved in triglyceride metabolism including apoB48 and apoA5 by LC/MS/MS." in: Journal of lipid research, Vol. 55, Issue 6, pp. 1179-87, (2016) (PubMed).

Saeed, El-Naga, El-Bakly, Abdel-Rahman, Salah ElDin, El-Demerdash: "Epigallocatechin-3-gallate pretreatment attenuates doxorubicin-induced cardiotoxicity in rats: A mechanistic study." in: Biochemical pharmacology, Vol. 95, Issue 3, pp. 145-55, (2015) (PubMed).

Chung, Park, Jung, Ha, Yoo, Woo, Lee, Kim, Kim, Moon, Yu: "Calpain Determines the Propensity of Adult Hippocampal Neural Stem Cells to Autophagic Cell Death Following Insulin Withdrawal." in: Stem cells (Dayton, Ohio), Vol. 33, Issue 10, pp. 3052-64, (2015) (PubMed).

Synonyms and alternative names related to Calpain 2

calpain 2 (CAPN2), calpain 2 (Capn2), calpain 2, gene2 (capn2.2), calpain 2, (m/II) large subunit b (capn2b), AI326419, CANP2, CANPL2, CANPml, Capa-2, Capa2, capn2, CAPN2, im:6908877, m-calpain, m-calpin, mCANP, zgc:109906

Protein level used designations for Calpain 2

  • CANP 2
  • M-calpain
  • calcium-activated neutral proteinase 2
  • calpain 2, large [catalytic] subunit
  • calpain 2, large subunit
  • calpain M-type
  • calpain large polypeptide L2
  • calpain, large polypeptide L2
  • calpain-2 catalytic subunit
  • calpain-2 large subunit
  • millimolar-calpain
  • 80 kDa M-calpain subunit
  • CALP80
  • cysteine proteinase
  • m-calpain 80 kDa large subunit
  • m-calpain large subunit
  • calpain 2
  • calpain 2, (m/II) large subunit b
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