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Caldesmon Products

(Caldesmon 1 (CALD1))

Categories

This gene encodes a calmodulin- and actin-binding protein that plays an essential role in the regulation of smooth muscle and nonmuscle contraction. The conserved domain of this protein possesses the binding activities to Ca(2+)-calmodulin, actin, tropomyosin, myosin, and phospholipids. This protein is a potent inhibitor of the actin-tropomyosin activated myosin MgATPase, and serves as a mediating factor for Ca(2+)-dependent inhibition of smooth muscle contraction. Alternative splicing of this gene results in multiple transcript variants encoding distinct isoforms. [provided by RefSeq, Jul 2008].

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Featured Caldesmon Categories

Caldesmon Antibodies

High quality antibodies with extensive validation data.

Caldesmon ELISA Kits

Reliable ELISA kits for a wide range of species.

Caldesmon Proteins

Proteins for various applications incl. WB, ELISA, IF etc.

Recommended Caldesmon Antibodies

Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, ELISA, FACS
Validations
  • (6)
Cat. No. ABIN7193477
Quantity 100 μL
Datasheet Datasheet
Reactivity Rat
Application WB, IHC, IP, ICC
Validations
  • (5)
Cat. No. ABIN7440557
Quantity 100 μL
Datasheet Datasheet
Reactivity Human, Mouse, Rat
Application WB, IHC, ELISA, IF, ICC
Validations
  • (5)
Cat. No. ABIN6255507
Quantity 100 μL
Datasheet Datasheet

Recommended Caldesmon ELISA Kits

Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6965335
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6962065
Quantity 96 tests
Datasheet Datasheet
Reactivity Human
Analytical Method Quantitative Sandwich ELISA
Validations
  • (1)
Cat. No. ABIN6954289
Quantity 96 tests
Datasheet Datasheet

Recommended Caldesmon Proteins

Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
  • (1)
Cat. No. ABIN7122098
Quantity 50 μg
Datasheet Datasheet
Reactivity Human
Source Wheat germ
Validations
  • (1)
Cat. No. ABIN1347883
Quantity 10 μg
Datasheet Datasheet
Reactivity Human
Source Escherichia coli (E. coli)
Validations
Cat. No. ABIN7411978
Quantity 100 μg
Datasheet Datasheet

Latest Publications for our Caldesmon products

Prayitnaningsih, Sujuti, Effendi, Abdullah, Anandita, Yohana, Permatasari, Widodo: "Neuropathy optic glaucomatosa induced by systemic hypertension through activation endothelin-1 signaling pathway in central retinal artery in rats." in: International journal of ophthalmology, Vol. 9, Issue 11, pp. 1568-1577, (2016) (PubMed).

Calon, Lonardo, Berenguer-Llergo, Espinet, Hernando-Momblona, Iglesias, Sevillano, Palomo-Ponce, Tauriello, Byrom, Cortina, Morral, Barceló, Tosi, Riera, Attolini, Rossell, Sancho, Batlle: "Stromal gene expression defines poor-prognosis subtypes in colorectal cancer." in: Nature genetics, Vol. 47, Issue 4, pp. 320-9, (2015) (PubMed).

Al-Shboul, Mustafa, Mohammad, Al-Shehabat, Yousef, Al-Hashimi: "Effect of oxidative stress on the expression of thin filament-associated proteins in gastric smooth muscle cells." in: Cell biochemistry and biophysics, Vol. 70, Issue 1, pp. 225-31, (2014) (PubMed).

Qundos, Hong, Tybring, Divers, Odeberg, Uhlen, Nilsson, Schwenk: "Profiling post-centrifugation delay of serum and plasma with antibody bead arrays." in: Journal of proteomics, Vol. 95, pp. 46-54, (2013) (PubMed).

Andersson, Konrad, Ashok, Pontén, Hober, Asplund: "Antibodies biotinylated using a synthetic Z-domain from protein A provide stringent in situ protein detection." in: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, Vol. 61, Issue 11, pp. 773-84, (2013) (PubMed).

Köhler: "The actin-binding protein caldesmon is in spleen and lymph nodes predominately expressed by smooth-muscle cells, reticular cells, and follicular dendritic cells." in: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, Vol. 58, Issue 2, pp. 183-93, (2012) (PubMed).

Stadler, Hjelmare, Neumann, Jonasson, Pepperkok, Uhlén, Lundberg: "Systematic validation of antibody binding and protein subcellular localization using siRNA and confocal microscopy." in: Journal of proteomics, Vol. 75, Issue 7, pp. 2236-51, (2012) (PubMed).

Köhler: "Histochemical localization of caldesmon in the CNS and ganglia of the mouse." in: The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society, Vol. 59, Issue 5, pp. 504-17, (2011) (PubMed).

Fagerberg, Stadler, Skogs, Hjelmare, Jonasson, Wiking, Abergh, Uhlén, Lundberg: "Mapping the subcellular protein distribution in three human cell lines." in: Journal of proteome research, Vol. 10, Issue 8, pp. 3766-77, (2011) (PubMed).

Pitts, Tan, Kulikowski, Tentler, Brown, Flanigan, Leong, Coldren, Hirsch, Varella-Garcia, Korch, Eckhardt: "Development of an integrated genomic classifier for a novel agent in colorectal cancer: approach to individualized therapy in early development." in: Clinical cancer research : an official journal of the American Association for Cancer Research, Vol. 16, Issue 12, pp. 3193-204, (2010) (PubMed).

Synonyms and alternative names related to Caldesmon

caldesmon 1 (CALD1), caldesmon 1 (Cald1), 4833423D12Rik, AI195384, AV071549, AW536160, C920027I18Rik, CALD1, Caldesmon, CDM, H-CAD, HCAD, L-CAD, l-Cad, LCAD, NAG22

Protein level used designations for Caldesmon

  • caldesmon
  • CDM
  • L-caldesmon
  • h-caldesmon
  • non-muscle caldesmon
  • caldesmon, smooth muscle
  • caldesmon 1
  • l-caldesmon
  • smooth muscle caldesmon
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