Cadherin 4 Products
(Cadherin 4 (CDH4))
Categories
This gene is a classical cadherin from the cadherin superfamily. The encoded protein is a calcium-dependent cell-cell adhesion glycoprotein comprised of five extracellular cadherin repeats, a transmembrane region and a highly conserved cytoplasmic tail. Based on studies in chicken and mouse, this cadherin is thought to play an important role during brain segmentation and neuronal outgrowth. In addition, a role in kidney and muscle development is indicated. Of particular interest are studies showing stable cis-heterodimers of cadherins 2 and 4 in cotransfected cell lines. Previously thought to interact in an exclusively homophilic manner, this is the first evidence of cadherin heterodimerization. Three transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Nov 2011].
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Featured Cadherin 4 Categories
Cadherin 4 Antibodies
High quality antibodies with extensive validation data.
Cadherin 4 ELISA Kits
Reliable ELISA kits for a wide range of species.
Cadherin 4 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended Cadherin 4 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IF, FACS, IHC (p)
Validations
- (1)
- (5)
Cat. No.
ABIN388148
Quantity
400 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IF, FACS, IHC (p), EIA
Validations
- (4)
Cat. No.
ABIN356865
Quantity
0.4 mL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA
Validations
- (2)
Cat. No.
ABIN560277
Quantity
100 μg
Datasheet
Datasheet
Recommended Cadherin 4 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN4882287
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6730333
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Human
Analytical Method
Semi-Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN6385128
Quantity
96 tests
Datasheet
Datasheet
Recommended Cadherin 4 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Source
Wheat germ
Validations
- (1)
Cat. No.
ABIN1348916
Quantity
10 μg
Datasheet
Datasheet
Reactivity
Human
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7403762
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
Cat. No.
ABIN7317950
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our Cadherin 4 products
: "Cadherins mediate cocaine-induced synaptic plasticity and behavioral conditioning." in: Nature neuroscience, Vol. 20, Issue 4, pp. 540-549, (2017) (PubMed).: "Chronic Replication Problems Impact Cell Morphology and Adhesion of DNA Ligase I Defective Cells." in: PLoS ONE, Vol. 10, Issue 7, pp. e0130561, (2015) (PubMed).
: "Delineation of the key aspects in the regulation of epithelial monolayer formation." in: Molecular and cellular biology, Vol. 33, Issue 13, pp. 2535-50, (2013) (PubMed).
: "Novel target genes responsive to the anti-growth activity of triptolide in endometrial and ovarian cancer cells." in: Cancer letters, Vol. 297, Issue 2, pp. 198-206, (2010) (PubMed).
: "R-cadherin influences cell motility via Rho family GTPases." in: The Journal of biological chemistry, Vol. 279, Issue 30, pp. 31041-9, (2004) (PubMed).
: "Frequent aberrant methylation of the CDH4 gene promoter in human colorectal and gastric cancer." in: Cancer research, Vol. 64, Issue 22, pp. 8156-9, (2004) (PubMed).
: "Mutation analysis of cadherin-4 reveals amino acid residues of EC1 important for the structure and function." in: Biochemical and biophysical research communications, Vol. 271, Issue 2, pp. 358-63, (2000) (PubMed).
: "Cloning of five human cadherins clarifies characteristic features of cadherin extracellular domain and provides further evidence for two structurally different types of cadherin." in: Cell adhesion and communication, Vol. 2, Issue 1, pp. 15-26, (1995) (PubMed).
: "Molecular cloning of mouse pancreatic islet R-cadherin: differential expression in endocrine and exocrine tissue." in: Molecular endocrinology (Baltimore, Md.), Vol. 7, Issue 9, pp. 1151-60, (1994) (PubMed).
: "Cell binding specificity of mouse R-cadherin and chromosomal mapping of the gene." in: Journal of cell science, Vol. 106 ( Pt 1), Issue 6, pp. 401-9, (1994) (PubMed).
Synonyms and alternative names related to Cadherin 4
cadherin 4 (cdh4), cadherin 4 (Cdh4), cadherin 4, type 1, R-cadherin (retinal) (cdh4), cadherin 4 (CDH4), Cadherin-4 (cdh-4), AW120700, cad4, CAD4, cadherin-4, Cdh4l, R-Cadh, R-cadherin, rcad, Rcad, RCAD, zgc:136316Protein level used designations for Cadherin 4
- cadherin 4, type 1, R-cadherin (retinal)
- R-CAD
- cadherin-4
- retina cadherin
- retinal cadherin
- R-cadherin
- cadherin 4 type 1 R-cadherin (retinal)
- cadherin 4, type 1, preproprotein
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