CACNA1H Products
(Calcium Channel, Voltage-Dependent, T Type, alpha 1H Subunit (CACNA1H))
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This gene encodes a T-type member of the alpha-1 subunit family, a protein in the voltage-dependent calcium channel complex. Calcium channels mediate the influx of calcium ions into the cell upon membrane polarization and consist of a complex of alpha-1, alpha-2/delta, beta, and gamma subunits in a 1:1:1:1 ratio. The alpha-1 subunit has 24 transmembrane segments and forms the pore through which ions pass into the cell. There are multiple isoforms of each of the proteins in the complex, either encoded by different genes or the result of alternative splicing of transcripts. Alternate transcriptional splice variants, encoding different isoforms, have been characterized for the gene described here. Studies suggest certain mutations in this gene lead to childhood absence epilepsy (CAE). [provided by RefSeq, Jul 2008].
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Featured CACNA1H Categories
CACNA1H Antibodies
High quality antibodies with extensive validation data.
CACNA1H ELISA Kits
Reliable ELISA kits for a wide range of species.
CACNA1H Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended CACNA1H Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, IP, IF, ICC, AA
Validations
- (3)
Cat. No.
ABIN2482861
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, IF, ICC, AA
Validations
- (3)
Cat. No.
ABIN2482860
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, IF, ICC, AA
Validations
- (3)
Cat. No.
ABIN2482859
Quantity
100 μg
Datasheet
Datasheet
Recommended CACNA1H ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6954277
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
Cat. No.
ABIN5652491
Quantity
96 tests
Datasheet
Datasheet
Recommended CACNA1H Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7407349
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
Escherichia coli (E. coli)
Validations
Cat. No.
ABIN7407346
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our CACNA1H products
: "Cav3.2 calcium channel interactions with the epithelial sodium channel ENaC." in: Molecular brain, Vol. 12, Issue 1, pp. 12, (2019) (PubMed).: "Brain-derived neurotrophic factor stimulation of T-type Ca2+ channels in sensory neurons contributes to increased peripheral pain sensitivity." in: Science signaling, Vol. 12, Issue 600, (2019) (PubMed).
: "T-type calcium channels functionally interact with spectrin (α/β) and ankyrin B." in: Molecular brain, Vol. 11, Issue 1, pp. 24, (2018) (PubMed).
: "Caveolae Link CaV3.2 Channels to BKCa-Mediated Feedback in Vascular Smooth Muscle." in: Arteriosclerosis, thrombosis, and vascular biology, Vol. 38, Issue 10, pp. 2371-2381, (2018) (PubMed).
: "Mechanism of direct Cav2.2 channel block by the κ-opioid receptor agonist U50488H." in: Neuropharmacology, Vol. 109, pp. 49-58, (2016) (PubMed).
: "TRPV1 Nociceptor Activity Initiates USP5/T-type Channel-Mediated Plasticity." in: Cell reports, Vol. 17, Issue 11, pp. 2901-2912, (2016) (PubMed).
: "Cholinergic afferent stimulation induces axonal function plasticity in adult hippocampal granule cells." in: Neuron, Vol. 85, Issue 2, pp. 346-63, (2015) (PubMed).
: "Eps15 Homology Domain-containing Protein 3 Regulates Cardiac T-type Ca2+ Channel Targeting and Function in the Atria." in: The Journal of biological chemistry, Vol. 290, Issue 19, pp. 12210-21, (2015) (PubMed).
: "The deubiquitinating enzyme USP5 modulates neuropathic and inflammatory pain by enhancing Cav3.2 channel activity." in: Neuron, Vol. 83, Issue 5, pp. 1144-58, (2014) (PubMed).
: "Inhibition of T-type calcium channels disrupts Akt signaling and promotes apoptosis in glioblastoma cells." in: Biochemical pharmacology, Vol. 85, Issue 7, pp. 888-97, (2013) (PubMed).
Synonyms and alternative names related to CACNA1H
calcium voltage-gated channel subunit alpha1 H (CACNA1H), calcium channel, voltage-dependent, T type, alpha 1H subunit (Cacna1h), calcium voltage-gated channel subunit alpha1 H (Cacna1h), alpha13.2, CACNA1HB, Cav3.2, ECA6, EIG6, MNCb-1209Protein level used designations for CACNA1H
- calcium channel, voltage-dependent, T type, alpha 1Hb subunit
- low-voltage-activated calcium channel alpha1 3.2 subunit
- low-voltage-activated calcium channel alpha13.2 subunit
- voltage dependent t-type calcium channel alpha-1H subunit
- voltage-dependent T-type calcium channel subunit alpha-1H
- voltage-gated calcium channel alpha subunit Cav3.2
- voltage-gated calcium channel alpha subunit CavT.2
- voltage-gated calcium channel subunit alpha Cav3.2
- T-type Cav3.2
- calcium channel alpha13.2 subunit
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