CA9 Products
(Carbonic Anhydrase IX (CA9))
Categories
Carbonic anhydrases (CAs) are a large family of zinc metalloenzymes that catalyze the reversible hydration of carbon dioxide. They participate in a variety of biological processes, including respiration, calcification, acid-base balance, bone resorption, and the formation of aqueous humor, cerebrospinal fluid, saliva, and gastric acid. They show extensive diversity in tissue distribution and in their subcellular localization. CA IX is a transmembrane protein and the only tumor-associated carbonic anhydrase isoenzyme known. It is expressed in all clear-cell renal cell carcinoma, but is not detected in normal kidney or most other normal tissues. It may be involved in cell proliferation and transformation. This gene was mapped to 17q21.2 by fluorescence in situ hybridization, however, radiation hybrid mapping localized it to 9p13-p12. [provided by RefSeq, Jul 2008].
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Featured CA9 Categories
CA9 Antibodies
High quality antibodies with extensive validation data.
CA9 ELISA Kits
Reliable ELISA kits for a wide range of species.
CA9 Proteins
Proteins for various applications incl. WB, ELISA, IF etc.
Recommended CA9 Antibodies
Product
Reactivity
Application
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Application
WB, IHC, ELISA
Validations
- (2)
- (6)
Cat. No.
ABIN1724883
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, IHC, IP, ICC
Validations
- (6)
Cat. No.
ABIN7437167
Quantity
100 μL
Datasheet
Datasheet
Reactivity
Human
Application
WB, ELISA, FACS
Validations
- (2)
- (5)
Cat. No.
ABIN1724882
Quantity
100 μL
Datasheet
Datasheet
Recommended CA9 ELISA Kits
Product
Reactivity
Analytical Method
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Human
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6954338
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Rat
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6965397
Quantity
96 tests
Datasheet
Datasheet
Reactivity
Mouse
Analytical Method
Quantitative Sandwich ELISA
Validations
- (1)
Cat. No.
ABIN6962827
Quantity
96 tests
Datasheet
Datasheet
Recommended CA9 Proteins
Product
Reactivity
Source
Validations
Cat. No.
Quantity
Datasheet
Reactivity
Cynomolgus
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7274013
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Human
Source
HEK-293 Cells
Validations
- (3)
Cat. No.
ABIN7274014
Quantity
100 μg
Datasheet
Datasheet
Reactivity
Mouse
Source
HEK-293 Cells
Validations
- (2)
Cat. No.
ABIN7274015
Quantity
100 μg
Datasheet
Datasheet
Latest Publications for our CA9 products
: "Pyrazole-sulfonamide scaffold featuring dual-tail strategy as apoptosis inducers in colon cancer." in: Scientific reports, Vol. 13, Issue 1, pp. 5782, (2023) (PubMed).: "Combining DNA Vaccine and AIM2 in H1 Nanoparticles Exert Anti-Renal Carcinoma Effects via Enhancing Tumor-Specific Multi-functional CD8+ T-cell Responses." in: Molecular cancer therapeutics, Vol. 18, Issue 2, pp. 323-334, (2019) (PubMed).
: "Hypoxia-related carbonic anhydrase IX expression is associated with unfavourable response to first-line therapy in classical Hodgkin's lymphoma." in: Histopathology, Vol. 74, Issue 5, pp. 699-708, (2019) (PubMed).
: "ONECUT2 is a driver of neuroendocrine prostate cancer. ..." in: Nature communications, Vol. 10, Issue 1, pp. 278, (2019) (PubMed).
: "Activation of the hypoxia pathway in breast cancer tissue and patient survival are inversely associated with tumor ascorbate levels." in: BMC cancer, Vol. 19, Issue 1, pp. 307, (2019) (PubMed).
: "Poor outcome in hypoxic endometrial carcinoma is related to vascular density. ..." in: British journal of cancer, Vol. 120, Issue 11, pp. 1037-1044, (2019) (PubMed).
: "Quaking orchestrates a post-transcriptional regulatory network of endothelial cell cycle progression critical to angiogenesis and metastasis." in: Oncogene, Vol. 38, Issue 26, pp. 5191-5210, (2019) (PubMed).
: "RNA-seq analysis of PHD and VHL inhibitors reveals differences and similarities to the hypoxia response." in: Wellcome open research, Vol. 4, pp. 17, (2019) (PubMed).
: "Tumor cell oxidative metabolism as a barrier to PD-1 blockade immunotherapy in melanoma." in: JCI insight, Vol. 4, Issue 5, (2019) (PubMed).
: "Volumetric Optoacoustic Imaging Unveils High-Resolution Patterns of Acute and Cyclic Hypoxia in a Murine Model of Breast Cancer." in: Cancer research, (2019) (PubMed).
Synonyms and alternative names related to CA9
carbonic anhydrase 9 (CA9), carbonic anhydrase 9 (CAH9), carbonic anhydrase 9 (Car9), CA9, Ca9, CAIX, MN, MN/CA9Protein level used designations for CA9
- carbonic anhydrase IX
- carbonic anhydrase 9
- CA-IX
- carbonate dehydratase IX
- membrane antigen MN homolog
- P54/58N
- RCC-associated antigen G250
- RCC-associated protein G250
- carbonic dehydratase
- membrane antigen MN
- pMW1
- renal cell carcinoma-associated antigen G250
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